When sixteen-year-old Kate, an aspiring playright, moves from New Jersey to attend high school in the South, she becomes embroiled in a controversy to remove the school's Confederate flag symbol.

At Fable Harbor University Hospital, five young men and women are immersed in the life-and-death world of medicine. As they shadow doctors and assist with medical procedures, they learn truths about life, love, and medicine that can't be taught in any classroom, and find out that it's all much harder than they ever imagined.

Love, Michigan, is famous for Winterfest, an annual athletic competition, but Tara, Erin, and Noelle are about to find out that there's a lot more to Winterfest than sports.