'For a salesman, there is no rock bottom to life. He don't put a bolt to a nut, he don't tell you the law or give you medicine. He's a man way out there in the blue, riding on a smile and a shoeshine.' Willy Loman has been a salesman for 34 years. At 60, he is cast aside, his usefulness now exhausted. With no future to dream about he must face the crushing disappointments of his past. He takes one final brave action, but is he heroic at last?, or a self-deluding fool?

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer, yet her cells--taken without her knowledge--became one of the most important tools in medicine. The first "immortal" human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer and viruses; helped lead to in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks is buried in an unmarked grave. Her family did not learn of her "immortality" until more than twenty years after her death, when scientists began using her husband and children in research without informed consent. The story of the Lacks family is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of--From publisher description.

Welcome to ninety-seven-hour weeks. Welcome to life-and-death decisions. Welcome to a constant tsunami of bodily fluids. Welcome to earning less than the hospital parking meter. Wave goodbye to your friends and relationships... Welcome to the life of a junior doctor. Scribbled in secret after endless days, sleepless nights and missed weekends, Adam Kay's diaries provide a no-holds-barred account of his time on the NHS front line. Hilarious, horrifying and heartbreaking by turns, this is everything you wanted to know - and more than a few things you didn't - about life on and off the hospital ward. And yes, it may leave a scar.

"Daniel Kahneman, recipient of the Nobel Prize in Economic Sciences for his seminal work in psychology that challenged the rational model of judgment and decision making, is one of our most important thinkers. His ideas have had a profound and widely regarded impact on many fields - including economics, medicine, and politics - but until now, he has never brought together his many years of research and thinking in one book. ... [He] explains the two systems that drive the way we think. System 1 is fast, intuitive, and emotional; System 2 is slower, more deliberative, and more logical. Kahneman exposes the extraordinary capabilities - and also the faults and biases - of fast thinking, and reveals the pervasive influence of intuitive impressions on our thoughts and behavior. ... reveals where we can and cannot trust our intuitions and how we can tap into the benefits of slow thinking. He offers practical and enlightening insights into how choices are made in both our business and our personal lives - and how we can use different techniques to guard against the mental glitches that often get us into trouble"--From jacket.

"A brilliant and brave investigation by Michael Pollan, author of five New York Times best sellers, into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into the experience of various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both struggle and beauty, we can do our best to be fully present and find meaning in our lives"--

A simple and straightforward introduction to Buddhist meditation practice from one of the country's leading authorities on stress-reduction techniques, Dr. Kabat-Zinn has taught this two-thousand-year-old Buddhist method of relaxation to thousands of patients.

From number one New York Times bestselling author Michael Pollan, a radical challenge to how we think about drugs, and an exploration into the powerful human attraction to psychoactive plants--and the equally powerful taboos Of all the things humans rely on plants for--sustenance, beauty, medicine, fragrance, flavor, fiber--surely the most curious is our use of them to change consciousness: to stimulate or calm, fiddle with or completely alter, the qualities of our mental experience. Take coffee and tea: People around the world rely on caffeine to sharpen their minds. But we do not usually think of caffeine as a drug, or our daily use as an addiction, because it is legal and socially acceptable. So, then, what is a "drug"? And why, for example, is making tea from the leaves of a tea plant acceptable, but making tea from a seed head of an opium poppy a federal crime? In This Is Your Mind on Plants , Michael Pollan dives deep into three plant drugs--opium, caffeine, and mescaline--and throws the fundamental strangeness, and arbitrariness, of our thinking about them into sharp relief. Exploring and participating in the cultures that have grown up around these drugs while consuming (or, in the case of caffeine, trying not to consume) them, Pollan reckons with the powerful human attraction to psychoactive plants. Why do we go to such great lengths to seek these shifts in consciousness, and then why do we fence that universal desire with laws and customs and fraught feelings? In this unique blend of history, science, and memoir, as well as participatory journalism, Pollan examines and experiences these plants from several very different angles and contexts, and shines a fresh light on a subject that is all too often treated reductively--as a drug, whether licit or illicit. But that is one of the least interesting things you can say about these plants, Pollan shows, for when we take them into our bodies and let them change our minds, we are engaging with nature in one of the most profound ways we can. Based in part on an essay published almost twenty-five years ago, this groundbreaking and singular consideration of psychoactive plants, and our attraction to them through time, holds up a mirror to our fundamental human needs and aspirations, the operations of our minds, and our entanglement with the natural world.

This is Going to Hurt was the publishing phenomenon of the century. It has been read by millions, translated into 37 languages, and adapted into a major BBC television series. But that was only part of the story. Now, Adam Kay returns and will once again have you in stitches in his painfully funny and startlingly powerful follow-up, Undoctored: The Story of a Medic Who Ran out of Patients. In his most honest and incisive book yet, he reflects on what's happened since hanging up his scrubs and examines a life inextricably bound up with medicine. Battered and bruised from his time on the NHS frontline, Kay looks back, moves forwards and opens up some old wounds. Hilarious and heartbreaking, horrifying and humbling, Undoctored is the astonishing portrait of a life by one of Britain's best-loved storytellers.

You will automatically receive a 3 month FREE subscription to Harrison's Online 2.0 with your purchase of the HARRISON textbook. Eminently readable, completely current, and dramatically revised, the new fifteenth edition of Harrison's PRINCIPLES OF INTERNAL MEDICINE raises the bar for internal medicine references. Featuring over 90 completely new chapters, HARRISON'S continues to provide the most authoritative record of internal medicine as practiced by the leading experts in the field. And it gives you the one comprehensive database that covers the full spectrum of issues you need to know NOW - basic science, pathophysiology, presenting clinical signs, diagnosis, and the latest treatment guidelines. * Expanded treatment with more algorithms and diagnostic decision trees * A new feature, Genetic Considerations, describes how new advances affect patient care * Clinical Guidelines now added throughout, provide evidence-based treatment strategies * Alternative Medicine...a detailed chapter covers this emerging field * New Chapter on Late Problems in Patients with Cancer * New guidelines on Adolescent Health Care * The latest in Gene Therapy with a new chapter on Screening, Prevention, and Counseling for Genetic Disorders * New chapter on Infertility and Fertility Control * Neurobiology of Disease highlights numerous advances made during "The disease of the Brain" * Late-breaking treatment information on multiple sclerosis, Parkinson's disease, Alzheimer's and more * A new color atlas of malaria-infected red blood cells

The Ornish Diet has been named the “#1 best diet for heart disease” by U.S. News & World Report for seven consecutive years! Dr. Dean Ornish is the first clinician to offer documented proof that heart disease can be halted, or even reversed, simply by changing your lifestyle. Based on his internationally acclaimed scientific study, which has now been ongoing for years, Dr. Ornish's program has yielded amazing results. Participants reduced or discontinued medications; they learned how to lower high blood pressure; their chest pain diminished or disappeared; they felt more energetic, happy, and calm; they lost weight while eating more; and blockages in coronary arteries were actually reduced. In his breakthrough book, Dr. Ornish presents this and other dramatic evidence and guides you, step-by-step, through the extraordinary Opening Your Heart program, which is winning landmark approval from America's health insurers. The program takes you beyond the purely physical side of health care to include the psychological, emotional and spiritual aspects so vital to healing. This book represents the best modern medicine has to offer. It can inspire you to open your heart to a longer, better, happier life.

The Eight-Week Program sets up a foundation for healthy living that is preventative in the broadest sense. Not only does Dr. Weil provide information with which you can keep your body's inherent healing system in peak working order as you encounter the challenges of day-to-day life; he also shows you how to construct a lifestyle that will protect you from premature illness and disability, and teaches practices and skills that will enable you to prepare for any eventual health crisis you may face. With clearly explained and authoritatively informed recommendations, Dr. Weil guides you in fine-tuning your current eating habits - to eat less fat and animal protein, more whole grains and other complex carbohydrates, and more fruits and vegetables - so that your diet becomes more nutritious and increasingly beneficial to general health (he also includes simple, flavorful recipes to help you make the dietary changes quickly and easily). He shows how walking and stretching will satisfy all your exercise requirements throughout your life, and provides a gradual plan by which you can make brisk forty-five-minute walks and some simple stretches part of your weekly regimen. Dr. Weil recommends the addition of four antioxidant supplements - vitamins C and E, selenium, and mixed carotenes - to further protect your healing system. He provides instruction in five basic breathing exercises that can impart both greater relaxation and energy. He discusses the benefits and techniques of visualization. He explains ways to overcome sleeping problems; to test and filter your water supply; to eliminate toxins from your diet; and to avoid environmental hazards such as the sun's ultraviolet rays. He suggestsways to make art, music, and the natural world more important parts of your life. For those who wish to experiment further, he outlines several projects and activities such as cleansing fasts. There are a dozen additional programs that concentrate on the specific needs of pregnant

"Traditionally, the goal of psychology has been to relieve human suffering, but the goal of the Positive Psychology movement, which Dr. Seligman has led for fifteen years, is different&—it's about actually raising the bar for the human condition. Flourish builds on Dr. Seligman's game-changing work on optimism, motivation, and character to show how to get the most out of life, unveiling an electrifying new theory of what makes a good life&—for individuals, for communities, and for nations. In a fascinating evolution of thought and practice, Flourish refines what Positive Psychology is all about. While certainly a part of well-being, happiness alone doesn't give life meaning. Seligman now asks, What is it that enables you to cultivate your talents, to build deep, lasting relationships with others, to feel pleasure, and to contribute meaningfully to the world? In a word, what is it that allows you to flourish? “Well-being” takes the stage front and center, and Happiness (or Positive Emotion) becomes one of the five pillars of Positive Psychology, along with Engagement, Relationships, Meaning, and Accomplishment&—or PERMA, the permanent building blocks for a life of profound fulfillment. Thought-provoking in its implications for education, economics, therapy, medicine, and public policy&—the very fabric of society&—Flourish tells inspiring stories of Positive Psychology in action, including how the entire U.S. Army is now trained in emotional resilience; how innovative schools can educate for fulfillment in life and not just for workplace success; and how corporations can improve performance at the same time as they raise employee well-being. With interactive exercises to help readers explore their own attitudes and aims, Flourish is a watershed in the understanding of happiness as well as a tool for getting the most out of life. "--Publisher.

The kids are not alright. The Left is waging an all-out battle on the American family, particularly the youngest members. If they can make our children miserable, lead them to question every building block of society, and rebuild their entire concept of reality, then the Left and their woke indoctrinators will consider that a victory. But we can't let them win. As concerned parents and American citizens, we have to understand what's truly going on before we can do something about it. Stolen Youth provides an urgent deep dive into issues surrounding the current woke indoctrination happening in politics, education, medicine, mental health, entertainment, and culture. These issues may seem subtle, insidious, and hard to make sense of, but armed with the information provided in this book, we now have a framework from which to fight. While we may simply be trying to parent our children well and create a healthy and happy home environment, this is no longer enough. We must now go on the offense to protect our kids, and this book sheds a bright light on the reason why. We can no longer afford to stay ignorant. Our children's lives and the survival of our families are at stake. "A win is a family who is free." Stolen Youth outlines how to fight for our children's freedom--and win.

In the winter of 1950, Margaret Sanger, then seventy-one, and who had campaigned for women's right to control their own fertility for five decades, arrived at a Park Avenue apartment building. She had come to meet a visionary scientist with a dubious reputation more than twenty years her junior. His name was Gregory Pincus. In The Birth of the Pill, Jonathan Eig tells the extraordinary story of how, prompted by Sanger, and then funded by the wealthy widow and philanthropist Katharine McCormick, Pincus invented a drug that would stop women ovulating. With the support of John Rock, a charismatic and, crucially, Catholic doctor from Boston, who battled his own church in the effort to win public approval for the controversial new drug, he succeeded. Together, these four determined men and women changed the world. Spanning the years from Sanger's heady Greenwich Village days in the early twentieth century to trial tests in Puerto Rico in the 1950s to the cusp of the sexual revolution in the 1960s, this is a grand story of radical feminism, scientific ingenuity, establishment opposition, and, ultimately, a sea change in social attitudes.

NATIONAL BESTSELLER • By the pioneer of lifestyle medicine, a simple, scientifically program proven to often reverse the progression of the most common and costly chronic diseases. Long rated “#1 for Heart Health” by U.S. News & World Report, Dr. Ornish’s Program has recently been shown to often improve cognition and function in patients with early-stage Alzheimer’s disease. Dr. Ornish’s program for reversing heart disease is now covered by Medicare when offered virtually at home. “The Ornishes’ work is elegant and simple and deserving of a Nobel Prize since it can change the world!”—Richard Carmona, MD, MPH, 17th Surgeon General of the U.S. Dean Ornish, M.D., has directed revolutionary research proving, for the first time, that lifestyle changes can often reverse—undo!—the progression of many of the most common and costly chronic diseases. Medicare and many insurance companies now cover Dr. Ornish’s lifestyle medicine program for reversing chronic disease because it consistently achieves bigger changes in lifestyle, better clinical outcomes, larger cost savings, and greater adherence than have ever been reported—based on over forty years of research published in the leading peer-reviewed medical and scientific journals. Now, in this landmark book, he and Anne Ornish present a simple yet powerful new unifying theory explaining why these same lifestyle changes can reverse so many different chronic diseases and how quickly these benefits occur. They describe what it is, why it works, and how you can do it: • Eat well : a whole foods, plant-based diet naturally low in fat and sugar and high in flavor • Move more : moderate exercise such as walking • Stress less : including meditation and gentle yoga practices • Love more : how love and intimacy transform loneliness into healing With seventy recipes, easy-to-follow meal plans, tips for stocking your kitchen and eating out, recommended exercises, stress-reduction advice, and inspiring patient stories of life-transforming benefits—for example, several people improved so much after only nine weeks they were able to avoid a heart transplant— Undo It! empowers readers with new hope and new choices.

NEW YORK TIMES BESTSELLER From the Nobel Prize-winning author of Thinking, Fast and Slow and the coauthor of Nudge, a revolutionary exploration of why people make bad judgments and how to make better ones--"a tour de force" ( New York Times ). Imagine that two doctors in the same city give different diagnoses to identical patients--or that two judges in the same courthouse give markedly different sentences to people who have committed the same crime. Suppose that different interviewers at the same firm make different decisions about indistinguishable job applicants--or that when a company is handling customer complaints, the resolution depends on who happens to answer the phone. Now imagine that the same doctor, the same judge, the same interviewer, or the same customer service agent makes different decisions depending on whether it is morning or afternoon, or Monday rather than Wednesday. These are examples of noise: variability in judgments that should be identical. In Noise , Daniel Kahneman, Olivier Sibony, and Cass R. Sunstein show the detrimental effects of noise in many fields, including medicine, law, economic forecasting, forensic science, bail, child protection, strategy, performance reviews, and personnel selection. Wherever there is judgment, there is noise. Yet, most of the time, individuals and organizations alike are unaware of it. They neglect noise. With a few simple remedies, people can reduce both noise and bias, and so make far better decisions. Packed with original ideas, and offering the same kinds of research-based insights that made Thinking, Fast and Slow and Nudge groundbreaking New York Times bestsellers, Noise explains how and why humans are so susceptible to noise in judgment--and what we can do about it.

Here David Oshinsky tells the gripping story of the polio terror and of the intense effort to find a cure, from the March of Dimes to the discovery of the Salk and Sabin vaccines--and beyond. Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family. Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life. Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

From the glittering ballrooms of Manhattan to the fires of World War I, #1 New York Times bestselling author Danielle Steel takes us on an unforgettable journey in this spellbinding tale of war, loss, history, and one woman’s unbreakable spirit. . . . Nineteen-year-old Annabelle Worthington was born into a life of privilege, raised amid the glamour of New York society, with glorious homes on Fifth Avenue and in Newport, Rhode Island. But everything changed on a cold April day in 1912, when the sinking of the Titanic shattered her family and her privileged world forever. Finding strength within her grief, Annabelle pours herself into volunteer work, nursing the poor, igniting a passion for medicine that would shape the course of her life. But for Annabelle, first love, and a seemingly idyllic marriage, will soon bring more grief—this time caused by the secrets of the human heart. Betrayed, and pursued by a scandal she does not deserve, Annabelle flees New York for war-ravaged France, hoping to lose herself in a life of service. There, in the heart of the First World War, in a groundbreaking field hospital run by women, Annabelle finds her true calling, working as an ambulance medic on the front lines, studying medicine, saving lives. And when the war ends, Annabelle begins a new life in Paris—now a doctor, a mother, her past almost forgotten . . . until a fateful meeting opens her heart to the world she had left behind. Finding strength in the most unlikely of friendships, pulling together the broken fragments of her life, Annabelle will return to New York one more time—this time as a changed woman, a woman of substance, infused with life’s experience, building a future filled with hope . . . out of the rich soil of the past. Filled with breathtaking images and historical detail, Danielle Steel’s novel introduces one of her most unique and fascinating characters: Annabelle Worthington, a remarkable woman, a good woman, a true survivor who triumphs against overwhelming odds. For Annabelle’s story is more than compelling fiction, it is a powerful celebration of life, dignity, and courage—and a testament to the human will to survive.

"How Doctors Think is a window into the mind of the physician and an insightful examination of the all-important relationship between doctors and their patients. In this myth-shattering work, Jerome Groopman explores the forces and thought processes behind the decisions doctors make. He pinpints why doctors succeed and why they err. Most important, Groopman shows when and how doctors can - with our help - avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health." --

"...This insightful book explores the scientific and psychological causes of addiction, as well as the impact on the addicts treated at the Downtown Eastside Vancouver clinic where Mate is a physician. He widens the lens to address the larger societal problem--speaking also to the risks of more "high-status" addictions, such as wealth, power, and sex. He boldly challenges the War on Drugs, proposing a more holistic, constructive set of alternatives. A riveting, debate-provoking book about an illness that reaches all levels of society, In the Realm of Hungry Ghosts provides a much-needed glimpse of hope from an innovator who is taking on addiction with startling clarity, vision, and wisdom."--Cover, p. 4.