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The discovery of how opiates such as morphine and heroin relieve pain and produce euphoria is one of the most dramatic tales of modern science. It begins in 1971 when, at the height of the undeclared war in Vietnam, Richard Nixon officially announced a war on drugs. Heroin addiction--no longer confined to urban ghettos--was causing bad public relations for the White House. The specter of young American soldiers demoralized, drugged, and committing atrocities was not the image President Nixon wished to convey as he argued for further bombings of North Vietnam. In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. Heroin or morphine molecules fit into opiate receptors much as a key fits into the ignition switch of a car--thus turning on the engine of the cell. Snyder and his students were able to show that nerve cells which possess opiate receptors are found in precisely those parts of the brain that control emotion and pain. Dr. Snyder describes the friendly yet intense competition from other researchers to expand upon this initial discovery. From the work of two Scottish investigators, Hans Kosterlitz and John Hughes, neuroscientists now know not only where opiate receptors are found in the brain but also why they are there: to serve as binding sites for an opiate-like substance produced by the brain itself--the brain's own morphine. This substance, called enkephalin, regulates pain, mood, and a host of other physiological functions. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work. We are reminded of the delicate political alliances that are forged at every level of organization, from the lab bench to the Oval Office, as the scientific community attempts to fit its needs to those of the larger society.

Gossip is no trivial matter; despite its reputation, Epstein argues, it is an eternal and necessary human enterprise. Proving that he himself is a master of the art, Epstein serves up delightful mini-biographies of the Great Gossips of the Western World, along with many choice bits from his own experience. He also makes a powerful case that gossip has morphed from its old-fashioned best--clever, mocking, a great private pleasure--to a corrosive new-school version, thanks to the reach of the mass media and the Internet. Written in his trademark erudite and witty style, Gossip captures the complexity of this immensely entertaining subject.

This tale of two families is set on a grand scale, as James Thomas Flexner brings his talents to bear on his own noteworthy heritage. An American Saga is an historical narrative, grounded on documentary sources, which ends with the marriage of Helen Thomas and Simon Flexner. The account deals equally with the lives and the backgrounds of husband and wife, the author's parents. Simon Flexner was the famous medical investigator, discoverer of the "Flexner vacillus" and the "Flexner serum," who became the creating director of the Rockefeller Institute for Medical Research (now Rockefeller University) and eventually acknowledged leader of American medical science. The Kentucky-born son of impoverished German Jewish immigrants, he grew up in penury. As he never completed the eighth grade, he was almost completely self-educated when he appeared at the Johns Hopkins University before its celebrated medical school had been founded. Almost instantly he began making the discoveries that soon made him the leading younger medical scientist in the United States.

The tobacco controversy is usually portrayed as a battle between selfless defenders of public health and greedy merchants of death. In For Your Own Good, journalist Jacob Sullum argues that such a view conceals the true nature of the crusade for a smoke-free society. As Sullum demonstrates, this struggle is not about the behavior of corporations; it's about the behavior of individuals. It is an attempt by one group of people to impose their tastes and preferences on another. For Your Own Good shows that long before Philip Morris or R.J. Reynolds existed, tobacco's opponents condemned smoking as disgusting, immoral, addictive, unhealthy, and inconsiderate. In recent decades, they have used scientific evidence that smoking is hazardous to enlist the state in their crusade, arguing that the government has an obligation to discourage behavior that might lead to disease or injury. Given this country's tradition of limited government, however, Americans tend to be skeptical of this argument. Sullum justifies their misgivings, noting that achieving a "smoke-free society" in a nation where tens of millions choose to smoke is necessarily an exercise in tyranny.

When a powerful mystic steps on the hand of a radical young hippie doctor from Detroit, it changes lives and the world. Sometimes Brilliant chronicles the adventures of a philosopher, seeker, unconventional doctor, groundbreaking tech innovator, and key player in the eradication of one of the worst pandemics in human history. His story--about what happens when love, compassion, and determination meet the right circumstances to effect positive change--is the kind that keeps hope and the sense of possibility alive. After sitting at the feet of Martin Luther King Jr. at the University of Michigan in 1963, Larry Brilliant was swept up into the civil rights movement, marching and protesting across America and Europe. As a radical young doctor, he followed the Hippie Trail from London over the Khyber Pass with his wife Girija, Wavy Gravy, and the Hog Farm commune to India. There, he found himself in a Himalayan ashram wondering whether he had stumbled into a cult. Instead, one of India's greatest spiritual teachers, Neem Karoli Baba, opened Larry's heart and told him his destiny was to work for the World Health Organization to help eradicate deadly smallpox. He never would have believed he'd become a key player in eliminating a ten-thousand-year-old disease that killed more than half a billion people in the twentieth century alone. Brilliant's unlikely trajectory, chronicled in Sometimes Brilliant, has brought him into close proximity with political leaders, spiritual masters, cultural heroes, and titans of technology around the world--from the Grateful Dead to Mikhail Gorbachev, from Ram Dass, the Dalai Lama, Lama Govinda, and Karmapa to Steve Jobs and the founders of Google, Salesforce, Facebook, Microsoft, and eBay, and Presidents Carter, Clinton, George W. Bush, and Obama. Anchored by the engrossing account of the heroic efforts of the extraordinary people involved in smallpox eradication in India, this is a riveting and fascinating epidemiological expedition, an honest reckoning of an entire generation, and a deeply moving spiritual memoir. It is a testament to faith, love, service, and what it means to engage with life's most important questions in pursuit of a better, more brilliant existence.

""Heil Hunger! Health Under Hitler"" is a non-fiction book written by Martin Gumpert. The book explores the impact of Nazi policies on the health and well-being of the German people during the Third Reich. Gumpert examines the various measures taken by the Nazi regime to promote health and fitness, including the establishment of physical education programs and the promotion of healthy eating habits. However, he also highlights the negative effects of Nazi policies, such as the forced sterilization of individuals deemed ""unfit"" and the mistreatment of concentration camp prisoners. Through extensive research and analysis, Gumpert provides a comprehensive look at the complex and often contradictory relationship between health and politics in Nazi Germany. Overall, ""Heil Hunger! Health Under Hitler"" offers a thought-provoking perspective on a dark period in history and the ways in which ideology can impact public health.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.

The man in the street would not, perhaps, recognize all the names of the brilliant scientists whose careers and personalities animate this book, but doctors know them. Morgan, who founded the first medical school in American and, fighting beside Washington, was ruined b the petty politics of the Revolution; McDowell, who, although on the fringe of the wilderness, dared the operation that prepared the way for all abdominal surgery; Rush, the equivocal personality who, for better or worse, dominated American medicine for more than fifty years; Beaumont, who, saving a life, won a living laboratory; Drake, who brought modern medicine to the New West; Long and Morton, who banished pain from surgery and earned it for themselves these men are honored in their profession today.

Although organ transplantation is the preeminent medical miracle of the last quarter of a century, Many Sleepless Nights is the first book to go beyond the headlines and describe the patients who have embraced this last chance to hold on to life, the intricate medical procedures that can save them, the surgeons and nurses who work in this emotionally charged world, and the ethics which complicate this miracle high-tech therapy. Lee Gutkind was granted unconditional access to the world's largest transplant center - the University of Pittsburgh's Presbyterian-University and Children's hospitals, where there is an organ transplant every eight hours, 365 days per year. For four years he immersed himself in the frantic night-and-day world of transplantation, living side by side with transplant candidates and recipients, jetting though the night with organ procurement teams, monitoring patients with surgeons and nurses, observing in the operating room, participating in the ethical and psychosocial evaluations of prospective patients which help to determine who will receive scarce organs. During his four years at Presbyterian and Children's Hospitals, Gutkind established close relationships with many patients, and his portrayal of them, living and sometimes dying under unbelievable stress, is a moving and dramatic statement about the capacity of human beings to endure. Many Sleepless Nights also outlines the history of organ transplantation and tells the story of the large and complex medical teams behind the operation. It captures the tension of the search for viable organs; the pressure decisions about which patients, among many, will receive them; and the surgery itself.Its vivid portrayal of the transplant pioneer Thomas Starzl - a man obsessed with saving lives - shows how a major innovator in American medicine functions during days and nights of extreme pressure.

This book is an intellectual and personal history of Richard Lazarus, a psychologist whose pioneering research and theories in stress, coping, and emotion continue to have a worldwide influence. The author interweaves the account of his personal life and career with the developments of psychology as an academic discipline during the past five decades. His reminiscences offer glimpses of academic life, university politics, and also his growing contacts with the European and Japanese colleagues who invited him to lecture. The book concludes with his thoughts about aging, retirement, and issues of life and death.

""The Medical Man and the Witch During the Renaissance"" by Gregory Zilboorg is a historical account of the relationship between medicine and witchcraft during the Renaissance period. The book explores how medical professionals, such as physicians and surgeons, interacted with individuals accused of practicing witchcraft and the role they played in the persecution of witches. Zilboorg delves into the cultural and social context of the time, examining the beliefs and superstitions that shaped the attitudes towards witches and the methods used to diagnose and treat supposed witchcraft. The book also examines the impact of the witch trials on the medical profession and the development of medical knowledge during this period. Overall, ""The Medical Man and the Witch During the Renaissance"" provides a fascinating insight into the intersection of medicine and witchcraft during a tumultuous period in European history.Publications Of Institute Of The History Of Medicine, The Johns Hopkins University, Third Series, V2.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.

Almost everything you know about heroin addiction is wrong. Not only is it wrong, but it is obviously wrong. Heroin is not highly addictive; withdrawal from it is not medically serious; addicts do not become criminals to feed their habit; addicts do not need any medical assistance to stop taking heroin; and contrary to received wisdom, heroin addiction most certainly IS a moral or spiritual problem. Based on his experience as a prison doctor and as a psychiatrist in a large general hospital in Birmingham, Dr. Dalrymple argues that addiction to heroin is not an illness at all, and that doctors only make it worse. They deceive both the addicts and themselves by pretending that they have something to offer. In this brilliant, entertaining and provocative book, Theodore Dalrymple explains how and why a literary tradition dating back to De Quincey and Coleridge, and continuing up to the deeply sociopathic William Burroughs and beyond, has misled all Western societies for generations about the nature of heroin addiction. These writers' self-dramatizing and dishonest accounts of their own addiction have been accepted uncritically, and have been more influential by far in forming public attitudes than the whole of pharmacological science. As a result, a self-serving, self-perpetuating and completely useless medical bureaucracy has been set up to deal with the problem. With scathing wit, implacable logic and savage denunciation, Dr. Dalrymple exposes the mythology surrounding heroin addiction. Moving seamlessly between literature, pharmacology, history and philosophy, he demonstrates what happens when the nature of a social problem is so thoroughly misunderstood, and when human beings are regarded as inanimate objects rather than as agents of their own destiny. His scintillating, iconoclastic little book has an importance far beyond its immediate subject matter.

Helene Deutsch was one of the most famous psychoanalysts to emerge from Freud's immediate circle in Vienna. Best known for her writings on female psychology, she was also one of the great teachers of psychoanalysis. As the founding president of the Vienna Psychoanalytic Training Institute, she confirmed her stature in the history of psychoanalysis by cultivating a whole younger generation of influential analysts. Deutsch was tolerant and open-minded, both as a theoretician and teacher, but, as Paul Roazen remarks in his introduction, independence and an absence of fanaticism can mean a temporary fading out of influence. For the first time, Deutsch's major professional contributions are brought together for permanent consideration. This volume documents her enduringly valuable exploration of the complexities of the psychology of women's experience. Deutsch remained essentially faithful to the Freudian canon. Nonetheless, and throughout these writings, she developed ideas on the subject of femininity that were often at odds with those of her mentor. Her use of Freud's theories aimed to encourage toleration of human diversity and to modify his model of sexuality according to the particular circumstances of women's lives. It was Deutsch who introduced motherhood as a central concern of psychoanalysis by stressing how the psychological dimension of reproduction was different for men and women and how this uniquely feminine capacity had its effects on the entire psychology of women. The same commitment to human diversity informs her much-misunderstood work on the clinical problems of female sexual dysfunction. While accepting the Freudian goal of sexual gratification, Deutsch argues that sublimation through work was a key value in its own right This is illustrated in "George Sand: A Woman's Destiny," a brilliant early example of psychobiography. This volume of Deutsch's classic papers, several appearing in English for the first time, will be of interest to psychologists, intellectual historians, and women's studies specialists.

With all the intrigue and twists of a mystery, Questions for Freud uncovers the paradoxes that riddle psychoanalysis today and traces them to Freud's vacillation at key points in his work--and from there to a traumatic event in Freud's life. What role did censored family history play in shaping Freud's psychological inquiries, promoting and impeding them by turns? With this question in mind, Nicholas Rand and Maria Torok develop a new biographical and conceptual approach to psychoanalysis, one that outlines Freud's contradictory theories of mental functioning against the backdrop of his permanent lack of insight into crucial and traumatic aspects of his immediate family's life. Taking us through previously unpublished documents and Freud's dreams, his clinical work and institutional organization, the authors show how a shameful event in 1865 that shook Freud and his family can help explain the internal clashes that later beset his work--on the origins of neurosis, reality, trauma, fantasy, sexual repression, the psychoanalytic study of literature, and dream interpretation. Steeped in the history, theory, and practice of psychoanalysis, this book offers a guide to the wary, a way of understanding the flaws and contradictions of Freud's thought without losing sight of its significance. This book will alter the terms of the current debate about the standing of psychoanalysis and Freud.

A luminous and insightful novel that considers the moral complexities of scientific discovery and the sustaining nature of love. A young researcher at MIT, Jane Weiss is obsessed with finding the genetic marker for Valentine’s Disease, a neurodegenerative disorder. Her pursuit is deeply personal—Valentine’s killed her mother, and she and her freewheeling sister, Laurel, could be genetic carriers; each has a fifty percent chance of developing the disease. Having seen firsthand the devastating effect Valentine’s had on her parents’ marriage, Jane is terrified she might become a burden on whomever she falls in love with and so steers clear of romantic entanglement. Then, the summer before her father’s second wedding, Jane falls hard for her future stepbrother, Willie. But Willie’s father also died from Valentine’s, raising the odds that their love will end in tragedy. When Willie bolts at a crucial moment in their relationship, Jane becomes obsessed with finding the genetic marker to the disease that threatens both their families. But if she succeeds in making history, will she and her sister have the courage to face the truth this newfound knowledge could hold for their lives? A Perfect Life is a novel of scientific and self discovery, about learning how to embrace life and love, no matter what may come. Eileen Pollack conjures a thought-provoking, emotionally resonant story of one woman’s brilliance and bravery as she confronts her deepest fears and desires—and comes to accept the inevitable and the unexpected.

It has been said that the only warriors who do not suffer after combat are those who were killed. I cannot attest to that for all battle tested warriors but I certainly can for one---me. Some years ago a young, 13 year old eighth grade student from the Fairfield, Iowa Middle School once asked me, "Were you wounded in the war? I had been invited to speak in Mrs. Broz's class for many years to talk about my wartime experiences. I had been asked and answered many questions but this one was different. I paused, thought deeply and quickly, and replied. "Yes I was wounded, seriously wounded but not a wound that anyone could see and fix." His question gave me pause to quickly think about warriors in all the wars that have been fought, including mine, whose wounds were unseen, untreated and debilitating even though no blood was shed. I spent a sleepless night wondering if my answer had satisfied him...or me. What was there about my military service that left me so hopeless and so helpless when I returned home to civilian life? Was it me? The military itself? The combat? This is what I recalled; perhaps the answers would come as I wrote my experiences down. "I've been practicing Transcendental Meditation for 40 years. It's a great tool for reducing stress ... especially the stress our men and women of the Armed Forces are going through now." --Clint Eastwood, Academy Award-Winning Film Director "Stress causes, anxiety, depression, and violent behavior. Transcendental Meditation is a remarkable process for reducing stress-it can help people live a long and better life." --Mehemet Oz, MD, America's Doctor "In this riveting memoir, a true American hero describes how Transcendental Meditation changed his life for good. A must-read for those struggling with the aftershocks of combat, and their loved ones." --Norman Rosenthal, M.D. Author of Transcendence: Healing and Transformation Through Meditation "The hidden cost of war includes long-term pain and suffering for may veterans and their families. This wonderful book shows how meditation can be a practical, simple, and effective way for our returning warriors to find peace." --Professor Linda Bilmes, Harvard University, co-author of The Three Trillion Dollar War "The Resilient warrior is a riveting read. What is especially impressive is how Jerry Yellin conflates his own war and PTSD experiences, and those experiences of other veterans, with the powerful compelling evidence of the benefits of using meditation as a means to overcome this disorder. I highly recommend this book to anyone seeking relief from stress, regardless of the source of the trauma." --Donald Mikkleson, Vietnam Veteran "My son, Dory, was an eight-year Army veteran who committed suicide early this year and I have suffered terribly. On a really bad day, a few weeks after Dory's death, Jerry Yellin suggested that I read The Resilient Warrior and learn to meditate. Since starting to meditate I can feel the stress leaving me, and my days and nights are getting a little better day-by-day, week-by-week. I strongly recommend Jerry's book to veterans and families of veterans, and anyone who is looking for a way of the nightmare of PTSD." --Lin Klock, Vero Beach, Florida Author Jerry Yellin Jerry was a WW 2 fighter pilot from Hillside, NJ. He flew P-51's over Japan from Iwo Jima. Married to Helene for 60 years, they have four sons and six grandchildren. Jerry is the author of the award winning historical fiction book The Blackened Canteen and his memoir Of War and Weddings . The soldier above all other people prays for peace, for he must suffer and bear the deepest wounds and scars of war." --General Douglas Macarthur

Exposes quack schemes and medical gimmicks that cheat the aged and calls for governmental action to educate the elderly consumer

Almost everyone has been touched by at least a mild form of depression, and thus has some sense of what severe depressive illness must be like. In addition to the most serious clinical cases which can lead to institutionalization or even suicide, this book explores the "normal" depression we all experience--the inevitable blues that accompany troubled personal relationships, career setbacks, or the death of a loved one. It provides a compelling treatment of questions about the nature of depression, where it comes from, who's at risk, and what it indicates about human experience. Depression is a highly prevalent health problem, affecting about 11 million Americans every year. Its costs are staggering - $43.7 billion annually in lost productivity, lost income, and increased health care costs. These numbers put depression on a par with heart disease as one of the most expensive diseases in the United States today. But, unlike heart disease, depression is widely misunderstood. About two-thirds of the cases of depression go undiagnosed and untreated. With a compelling mix of information, illustration, and interpretation, David B. Cohen explores the current state of knowledge about depression, including the powerful influence of genetics. In addition to depressive illness, the book deals with related ideas and topics such as mourning, mania, the rhythms of sleep, self concepts, and suicide. Insights from psychology and psychiatry are blended with history, literature, current events, and personal observation, and topped off with a dose of common sense.

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""The History of Miners' Diseases: A Medical and Social Interpretation"" by George Rosen is a comprehensive exploration of the health hazards and illnesses that miners have faced throughout history. The book delves into the medical and social aspects of these diseases, examining how they have been caused and how they have impacted the lives of miners and their families.Rosen begins by discussing the various types of mining, from coal to gold, and how each type of mining has its own unique set of hazards. He then goes on to explore the diseases that miners have faced over the centuries, including lung diseases like silicosis and black lung, as well as other illnesses like lead poisoning and tuberculosis.Throughout the book, Rosen examines the social and economic factors that have contributed to the spread of these diseases, including poor working conditions, inadequate safety measures, and the lack of access to medical care. He also discusses the efforts that have been made over the years to improve the health and safety of miners, from the introduction of safety regulations to the development of new medical treatments.Overall, ""The History of Miners' Diseases: A Medical and Social Interpretation"" provides a fascinating and informative look at the challenges that miners have faced throughout history. It is a must-read for anyone interested in the history of mining, public health, and social justice.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.