From the best-selling author of Why We Get Fat, a groundbreaking, eye-opening exposé that makes the convincing case that sugar is the tobacco of the new millennium: backed by powerful lobbies, entrenched in our lives, and making us very sick. Among Americans, diabetes is more prevalent today than ever; obesity is at epidemic proportions; nearly 10% of children are thought to have nonalcoholic fatty liver disease. And sugar is at the root of these, and other, critical society-wide, health-related problems. With his signature command of both science and straight talk, Gary Taubes delves into Americans' history with sugar: its uses as a preservative, as an additive in cigarettes, the contemporary overuse of high-fructose corn syrup. He explains what research has shown about our addiction to sweets. He clarifies the arguments against sugar, corrects misconceptions about the relationship between sugar and weight loss; and provides the perspective necessary to make informed decisions about sugar as individuals and as a society.

Joining the ranks of modern myth busters, Dr. Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria. So why does disease exist? Moalem proposes that most common ailments--diabetes, hemochromatosis, cystic fibrosis, sickle cell anemia--came into existence for very good reasons. At some point they helped our ancestors survive some grand challenge to their existence. Examining the evolution of man, Moalem reveals the role genetic and cultural differences have played in the health and well-being of various races, including their susceptibility to disease. With mesmerizing insight, Moalem offers groundbreaking insight into: - How diabetes may be a biproduct of a mechanism that helped humans survive the Ice Age - Why African Americans living in the north might suffer from vitamin D deficiencies, - Why Asians can't drink as much alcohol as Europeans Revelatory, utterly engaging, and timely--Moalem ponders strongN1, the emerging Avian Flu virus--Why Redheads Feel More Pain and Asians Can't Drink will irrevocably change the way we think about our bodies and ourselves.

Sam Harris's first book, The End of Faith , ignited a worldwide debate about the validity of religion. In the aftermath, Harris discovered that most people - from religious fundamentalists to nonbelieving scientists - agree on one point- science has nothing to say on the subject of human values. Indeed, our failure to address questions of meaning and morality through science has now become the primary justification for religious faith. In this highly controversial book, Sam Harris seeks to link morality to the rest of human knowledge. Defining morality in terms of human and animal well-being, Harris argues that science can do more than tell how we are; it can, in principle, tell us how we ought to be. In his view, moral relativism is simply false - and comes at an increasing cost to humanity. And the intrusions of religion into the sphere of human values can be finally repelled- for just as there is no such thing as Christian physics or Muslim algebra, there can be no Christian or Muslim morality. Using his expertise in philosophy and neuroscience, along with his experience on the front lines of our 'culture wars', Harris delivers a game-changing book about the future of science and about the real basis of human cooperation.

Bringing a fresh, secular perspective to age-old questions of right and wrong, and good and evil, the author shows that we know enough about the human brain and how it reacts to events in the world to say that there are right and wrong answers to the most pressing questions of human life.

As he guides readers through the surprising depth of canine emotional complexity, Jeffrey Masson draws from myth and literature, from scientific studies, and from the stories and observations of dog trainers and dog lovers around the world. But the stars of the book are Masson's own three dogs - Sasha, Sima, and Rani - whose delightful and mysterious behavior provides the way to exploring a wide range of subjects - from emotions like gratitude, compassion, loneliness, and disappointment to speculating what dogs dream of, how they perceive of other species (including humans), and how their powerful sense of smell shapes their perception of reality. As he sweeps aside old prejudices on animal behavior, Masson navigates through the rich universe of dog feeling to its essential core, their master emotion: love.

An eye-opening investigation into the history of diabetes research and treatment by the award-winning journalist and best-selling author of Why We Get Fat • "[Gary] Taubes’s meticulous, science-based work makes him the Bryan Stevenson of nutrition, an early voice in the wilderness for an unorthodox view that is increasingly becoming accepted."—Niel Barsky , The Guardian Before the discovery of insulin, diabetes was treated almost exclusively through diet, from subsistence on meat, to reliance on fats, to repeated fasting and near-starvation regimens. After two centuries of conflicting medical advice, most authorities today believe that those with diabetes can have the same dietary freedom enjoyed by the rest of us, leaving the job of controlling their disease to insulin therapy and other blood-sugar-lowering medications. Rather than embark on “futile” efforts to restrict sugar or carbohydrate intake, people with diabetes can lead a normal life, complete with the occasional ice-cream cake, side of fries, or soda. These guiding principles, however, have been accompanied by an explosive rise in diabetes over the last fifty years, particularly among underserved populations. And the health of those with diabetes is expected to continue to deteriorate inexorably over time, with ever-increasing financial, physical, and psychological burdens. In Rethinking Diabetes, Gary Taubes explores the history underpinning the treatment of diabetes, types 1 and 2, elucidating how decades-old research that is rife with misconceptions has continued to influence the guidance physicians offer—at the expense of their patients’ long-term well-being. The result of Taubes’s work is a reimagining of diabetes care that argues for a recentering of diet—particularly, fewer carbohydrates and more fat—over a reliance on insulin. Taubes argues critically and passionately that doctors and medical researchers should question the established wisdom that may have enabled the current epidemic of diabetes and obesity, and renew their focus on clinical trials to resolve controversies that are now a century in the making.

Here are some facts: Women live longer than men. They have stronger immune systems. They're better at fighting cancer and surviving famine, and even see the world in a wider variety of colours. They are simply stronger than men at every stage of life. Why is this? And why are we taught the opposite? To find out, Dr. Sharon Moalem drew on his own medical experiences - treating premature babies in the neonatal intensive care unit; recruiting the elderly for neurogenetic studies; tending to HIV-positive orphans in Thailand - and tried to understand why in every instance men were consistently less likely to thrive. The answer, he discovered, lies in our genetics: two X chromosomes offer a powerful survival advantage. With clear, captivating prose that weaves together eye-opening research, case studies, diverse examples ranging from the behaviour of honeybees to American pioneers, as well as experiences from his personal life and his own patients, Moalem explains why genetic females triumph over males when it comes to resiliency, intellect, stamina, immunity and much more. He also calls for a reconsideration of our male-centric, one-size-fits-all view of medical studies and even how we prescribe medications - a view that still sees women through the lens of men. Revolutionary and yet utterly convincing, The Better Half will make you see humanity and the survival of our species anew.[Bokinfo]

Instant New York Times bestseller! A Winner of the Barondess/Lincoln Award A Washington Independent Review of Books Favorite Book of 2018 A Suspense Magazine Best Book of 2018 A Mental Floss Best Book of 2018 A USA Today Top 10 Hot Book for Summer "Makes you feel as if you are watching a live camera riveted on a courtroom more than 150 years ago." --Diane Sawyer The true story of Abraham Lincoln's last murder trial, a case in which he had a deep personal involvement--and which played out in the nation's newspapers as he began his presidential campaign At the end of the summer of 1859, twenty-two-year-old Peachy Quinn Harrison went on trial for murder in Springfield, Illinois. Abraham Lincoln was hired to defend him. This was to be his last great case as a lawyer. What normally would have been a local case took on momentous meaning. Lincoln's debates with Stephen Douglas had gained him a national following. He was being urged to make a run for the presidency. His reputation was untarnished, but should he lose this trial, the spotlight now focused so brightly on him might be dimmed. The case also posed personal challenges for Lincoln. The victim had trained for the law in his office, and Lincoln had been his friend and his mentor. The accused killer, the young man Lincoln would defend, was the son of a close friend and supporter. And to win this trial he would have to form an allegiance with a bitter political rival. Lincoln's Last Trial captures the presidential hopeful's dramatic courtroom confrontations in vivid detail as he fights for his client--but also for his own political future.

Contains a story by Terry Pratchett, around which Stewart and Cohen write about the Discworld.

Two bestselling authors first met in a televised Caltech debate on “the future of God,” one an articulate advocate for spirituality, the other a prominent physicist. This remarkable book is the product of that serendipitous encounter and the contentious—but respectful—clash of worldviews that grew along with their friendship. In War of the Worldviews these two great thinkers battle over the cosmos, evolution and life, the human brain, and God, probing the fundamental questions that define the human experience. How did the universe emerge? What is the nature of time? What is life? Did Darwin go wrong? What makes us human? What is the connection between mind and brain? Is God an illusion? This extraordinary book will fascinate millions of readers of science and spirituality alike, as well as anyone who has ever asked themselves, What does it mean that I am alive?

NATIONAL BESTSELLER • “Exciting and provocative . . . A tour de force of a book that begs to be seen as well as to be read.”— The Washington Post Book World World renowned scientist Carl Sagan and acclaimed author Ann Druyan have written a Roots for the human species, a lucid and riveting account of how humans got to be the way we are. Shadows of Forgotten Ancestors is a thrilling saga that starts with the origin of the Earth. It shows with humor and drama that many of our key traits—self-awareness, technology, family ties, submission to authority, hatred for those a little different from ourselves, reason, and ethics—are rooted in the deep past, and illuminated by our kinship with other animals. Sagan and Druyan conduct a breathtaking journey through space and time, zeroing in on critical turning points in evolutionary history, and tracing the origins of sex, altruism, violence, rape, and dominance. Their book culminates in a stunningly original examination of the connection between primate and human traits. Astonishing in its scope, brilliant in its insights, and an absolutely compelling read, Shadows of Forgotten Ancestors is a triumph of popular science.

WHAT ARE THESE GRACEFUL VISITORS TO OUR SKIES? WE NOW KNOW THAT THEY BRING BOTH LIFE AND DEATH AND TEACH US ABOUT OUR ORIGINS. Comet begins with a breathtaking journey through space astride a comet. Pulitzer Prize-winning astronomer Carl Sagan, author of Cosmos and Contact, and writer Ann Druyan explore the origin, nature, and future of comets, and the exotic myths and portents attached to them. The authors show how comets have spurred some of the great discoveries in the history of science and raise intriguing questions about these brilliant visitors from the interstellar dark. Were the fates of the dinosaurs and the origins of humans tied to the wanderings of a comet? Are comets the building blocks from which worlds are formed? Lavishly illustrated with photographs and specially commissioned full-color paintings, Comet is an enthralling adventure, indispensable for anyone who has ever gazed up at the heavens and wondered why. "SIMPLY THE BEST." *The Times of London "FASCINATING, EVOCATIVE, INSPIRING." *The Washington Post "COMET HUMANIZES SCIENCE. A BEAUTIFUL, INTERESTING BOOK." *United Press International "MASTERFUL . . . SCIENCE, POETRY, AND IMAGINATION." *The Atlanta Journal & Constitution

NATIONAL BESTSELLER “Magnificent.” — The New York Times * “Beguiling, observant, and howlingly funny.” — San Francisco Chronicle * “Spectacular.” — Star Tribune (Minneapolis) * “Full of astonishments.” — The Boston Globe Susan Orlean—the beloved New Yorker staff writer hailed as “a national treasure” by The Washington Post and the author of the New York Times bestseller The Library Book —gathers a lifetime of musings, meditations, and in-depth profiles about animals. “How we interact with animals has preoccupied philosophers, poets, and naturalists for ages,” writes Susan Orlean. Since the age of six, when Orlean wrote and illustrated a book called Herbert the Near-Sighted Pigeon , she’s been drawn to stories about how we live with animals, and how they abide by us. Now, in On Animals , she examines animal-human relationships through the compelling tales she has written over the course of her celebrated career. These stories consider a range of creatures—the household pets we dote on, the animals we raise to end up as meat on our plates, the creatures who could eat us for dinner, the various tamed and untamed animals we share our planet with who are central to human life. In her own backyard, Orlean discovers the delights of keeping chickens. In a different backyard, in New Jersey, she meets a woman who has twenty-three pet tigers—something none of her neighbors knew about until one of the tigers escapes. In Iceland, the world’s most famous whale resists the efforts to set him free; in Morocco, the world’s hardest-working donkeys find respite at a special clinic. We meet a show dog and a lost dog and a pigeon who knows exactly how to get home. Equal parts delightful and profound, enriched by Orlean’s stylish prose and precise research, these stories celebrate the meaningful cross-species connections that grace our collective existence.

"Titillating and provocative essays from one of the freshest voices in science today -- Why do testicles hang the way they do? Is there an adaptive function to the female orgasm? What does it feel like to want to kill yourself? Does "free will" really exist? And why is the penis shaped like that anyway? In Why Is the Penis Shaped Like That?, the research psychologist and award-winning columnist Jesse Bering features more than thirty of his most popular essays from Scientific American and Slate, as well as two new pieces, that take readers on a bold and captivating journey through some of the most taboo issues related to evolution and human behavior. Exploring the history of cannibalism, the neurology of people who are sexually attracted to animals, the evolution of human body fluids, the science of homosexuality, and serious questions about life and death, Bering astutely covers a generous expanse of our kaleidoscope of quirks and origins. With his characteristic irreverence and trademark cheekiness, Bering leaves no topic unturned or curiosity unexamined, and he does it all with an audaciously original voice. Whether you are interested in the psychological history behind the many facets of sexual desire or the evolutionary patterns that have dictated our current mystique and phallic physique, Why Is the Penis Shaped Like That? is bound to create lively discussion and debate for years to come"--

How did a near-extinct species, eking out a meager existence with stone axes, become the dominant power on earth, able to harness a knowledge of nature ranging from tiny atoms to the vast structures of the universe? Leonard Mlodinow takes us on an enthralling tour of the history of human progress, from our time on the African savannah through the invention of written language, all the way to modern quantum physics. Along the way, he explores the colorful personalities of the great philosophers, scientists, and thinkers, and traces the cultural conditions—and the elements of chance—that influenced scientific discovery. Deeply informed, accessible, and infused with the author’s trademark humor and insight, The Upright Thinkers is a stunning tribute to humanity’s intellectual curiosity and an important book for any reader with an interest in the scientific issues of our day.

The untold story of the historic voyage to the moon that closed out one of our darkest years with a nearly unimaginable triumph In August 1968, NASA made a bold decision: in just sixteen weeks, the United States would launch humankind's first flight to the moon. Only the year before, three astronauts had burned to death in their spacecraft, and since then the Apollo program had suffered one setback after another. Meanwhile, the Russians were winning the space race, the Cold War was getting hotter by the month, and President Kennedy's promise to put a man on the moon by the end of the decade seemed sure to be broken. But when Frank Borman, Jim Lovell and Bill Anders were summoned to a secret meeting and told of the dangerous mission, they instantly signed on. Written with all the color and verve of the best narrative non-fiction, Apollo 8 takes us from Mission Control to the astronaut's homes, from the test labs to the launch pad. The race to prepare an untested rocket for an unprecedented journey paves the way for the hair-raising trip to the moon. Then, on Christmas Eve, a nation that has suffered a horrendous year of assassinations and war is heartened by an inspiring message from the trio of astronauts in lunar orbit. And when the mission is over--after the first view of the far side of the moon, the first earth-rise, and the first re-entry through the earth's atmosphere following a flight to deep space--the impossible dream of walking on the moon suddenly seems within reach. The full story of Apollo 8 has never been told, and only Jeffrey Kluger--Jim Lovell's co-author on their bestselling book about Apollo 13--can do it justice. Here is the tale of a mission that was both a calculated risk and a wild crapshoot, a stirring account of how three American heroes forever changed our view of the home planet.

The exclusive, first-hand, behind-the-scenes story of how Pfizer raced to create the first Covid-19 vaccine, told by Pfizer's CEO Dr. Albert Bourla A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made "the impossible possible"--creating, testing, and manufacturing a safe and effective Covid-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer, under the enormous strains of the global pandemic, overcame a series of crises that were compounded by social and political unrest, and reveals the doubts, decisions, obstacles, and failures they encountered. As Dr. Bourla makes clear, Pfizer's success wasn't due to luck; it was because of preparation driven by four simple values--Courage, Excellence, Equity, and Joy. Moonshot is a story of leadership under the most unprecedented circumstances--how Dr. Bourla, a Greek immigrant, a child of Holocaust survivors, and a veterinarian, became the head of one of the world's largest corporations and initiated a dramatic transformation of the organization just before a global health crisis would serve to test the organization, its scientists and its leader, like never before. Moonshot describes best practices that can be used to address the multiple, unprecedented challenges our world faces, reveals Pfizer's implementation of scientific breakthroughs at a record-breaking pace, and offers leadership lessons that can help anyone successfully manage their own seemingly unsolvable problems. As Dr. Bourla explains, "I am sharing the story of our moonshot--the challenges we faced, the lessons we learned, and the core values that allowed us to make it happen--in hopes that it might inspire and inform your own moonshot, whatever that may be."

“The articles . . . draw the reader more tightly into the web of the world. They forge links in unexpected ways. They connect us to nature and to each other, and those connections nourish the intellect and uplift the spirit.”—Jerome Groopman, M.D., editor This year’s Best American Science and Nature Writing offers another rich assortment of “fascinating science and impressive journalism” (New Scientist) culled from an array of periodicals, such as The New Yorker, Scientific American, and National Geographic. The twenty-four provocative and often visionary stories chosen by guest editor Jerome Groopman form an outstanding sampling of the very best in a field of writing that stays ahead of the curve, bringing important topics to the forefront of American discussion. In “The Universe’s Invisible Hand,” Christopher Conselice takes us into the recent spectacular discovery of the crucial role of dark energy, which is making our universe expand faster and faster. Florence Williams tells the story of a more down-to-earth form of energy in “A Mighty Wind,” which describes how a small Danish island community is making great leaps in energy conservation by using innovative wind farms. John Cohen explores the marvelous world of ligers, zorses, wholphins, and other hybridized creatures in “Zonkeys Are Pretty Much My Favorite Animal.” And Robin Marantz Henig delves into the possibly hazardous ramifications of the rapidly expanding science of nanotechnology. The Best American Science and Nature Writing 2008 packs a wallop of intriguing, informative, and wondrous stories, each one bringing with it, as Jerome Groopman writes, “a sense of excitement [to be] shared with others.”

Soul Made Flesh is the remarkable untold story of a dramatic turning point in history, the exciting discovery of how the human brain works. In an unprecedented examination of how the secrets of the brain were revealed in seventeenth-century England, award-winning author Carl Zimmer tells an extraordinary tale that unfurls against a deadly backdrop of civil war, plague, and the Great Fire of London. At the beginning of that turbulent century, no one knew how the brain worked or even what it looked like intact. By the century's close, the science of the brain had taken root, helping to overturn many of the most common misconceptions and dominant philosophies about man, God, and the universe. Presiding over the rise of this new scientific paradigm was the founder of modern neurology, Thomas Willis, a fascinating, sympathetic, even heroic figure who stands at the center of an extraordinary group of scientists and philosophers known as the Oxford circle. Chronicled here in vivid detail are their groundbreaking revelations and often gory experiments that first enshrined the brain as the chemical engine of reason, emotion, and madness, indeed as the very seat of the human soul. Called 'as fine a science essayist as we have' by The New York Times, Zimmer tells the story of this scientific revolution through the lives of a colorful array of alchemists, mystics, utopians, spies, revolutionaries, and kings. He recreates the religious, ethical, and scientific struggles involved in the pioneering autopsies of the brain carried out by Thomas Willis; the discovery of the circulation of blood by William Harvey and his flight from London with his besieged king, Charles I; René Descartes's persecution by Catholics and Protestants alike for his views of the brain and soul; and the experiments and personal dramas of gifted men who forever changed the way science is practiced as they simultaneously upended our view of our human selves and our place in the world. In this distant mirror to our own time of continuing scientific revolution and worldwide social upheaval, Zimmer brings to life the painstaking, innovative discoveries of Willis and his contemporaries, the taproots of the amazing work of today's neuroscientists, who continue to explore the brain, revealing the hidden workings of emotions, memories, and consciousness. Graced with beautiful illustrations by Christopher Wren, Soul Made Flesh conveys a contagious appreciation for the wonder of the brain, its structure, its many marvelous functions, and the implications for human identity, mind, and morality. It is the definitive history of the dawn of a world-changing science and attitude, the age of the brain and modern consciousness.

"Like the bestselling Infinite City: A San Francisco Atlas, this book is a brilliant reinvention of the traditional atlas, one that provides a vivid, complex look at the multi-faceted nature of New Orleans, a city replete with contradictions. More than twenty essays assemble a chorus of vibrant voices, including geographers, scholars of sugar and bananas, the city's remarkable musicians, prison activists, environmentalists, Arab and Native voices, and local experts, as well as the coauthors' compelling contributions. Featuring 22 full-color two-page-spread maps, Unfathomable City plumbs the depths of this major tourist destination, pivotal scene of American history and culture and, most recently, site of monumental disasters such as Hurricane Katrina and the BP oil spill. The innovative maps' precision and specificity shift our notions of the Mississippi, the Caribbean, Mardi Gras, jazz, soils and trees, generational roots, and many other subjects, and expand our ideas of how any city is imagined and experienced. Together with the inspired texts, they show New Orleans as both an imperiled city-by erosion, crime, corruption, and sea level rise-and an ageless city that lives in music as a form of cultural resistance. Compact, lively, and completely original, Unfathomable City takes readers on a tour that will forever change the way they think about place. "--