For millennia, human survival depended on our innate abilities to fight pathogens and repair injuries. Only recently has medical science prolonged longevity and improved quality of life. Physicians and academic researchers contribute to such progress, but the principal contributor is private industry that produces the tools – drugs and medical devices – enabling doctors to prevent and cure disease. Heavy regulation and biology’s complexity and unpredictability make medical innovation extremely difficult and expensive. Pharmaphobia describes how an ideological crusade, stretching over the last quarter century, has used distortion and flawed logic to make medical innovation even harder in a misguided pursuit of theoretical professional purity. Bureaucrats, reporters, politicians, and predatory lawyers have built careers attacking the medical products industry, belittling its critical contributions to medical innovation and accusing it of non-existent malfeasance: overselling product value, flaunting safety and corrupting physicians and academics who partner with it. The mania has imposed “conflict-of-interest” regulations limiting or banning valuable interactions between industry and physicians and researchers and diverting scarce resources from innovation to compliance. The victims are patients suffering from cancer, dementia, and other serious diseases for which new treatments are delayed, reduced, or eliminated as a result of these pointless regulations. With breathtaking detail, Thomas Stossel shows how this attack on doctors who work with industry limits medical innovation and inhibits the process of bringing new products into medical care.

This tale of two families is set on a grand scale, as James Thomas Flexner brings his talents to bear on his own noteworthy heritage. An American Saga is an historical narrative, grounded on documentary sources, which ends with the marriage of Helen Thomas and Simon Flexner. The account deals equally with the lives and the backgrounds of husband and wife, the author's parents. Simon Flexner was the famous medical investigator, discoverer of the "Flexner vacillus" and the "Flexner serum," who became the creating director of the Rockefeller Institute for Medical Research (now Rockefeller University) and eventually acknowledged leader of American medical science. The Kentucky-born son of impoverished German Jewish immigrants, he grew up in penury. As he never completed the eighth grade, he was almost completely self-educated when he appeared at the Johns Hopkins University before its celebrated medical school had been founded. Almost instantly he began making the discoveries that soon made him the leading younger medical scientist in the United States.

If news stories and the Internet are to be believed, the dangers from chemicals are increasing, cancer stalks us at every turn and our children are vulnerable. Synthetic chemicals are essential for modern life, but our views of them are conflicted. Pharmaceuticals keep us healthy. Plastics are found in everything from toys to cars to medical supplies. Pesticides and herbicides boost food production and quality. It's impossible to conceive of life in the 21st century without the materials and fuels that synthetic chemicals have made possible. But from soap to sunscreens, drugs to DDT, we are faced with an endless stream of confusing messages about the safety of chemicals we come in contact with every day. How does the public adjudge hazard, safety and risk? Presented by the American Council on Science and Health, in Scared to Death: How Chemophobia Threatens Public Health, journalist and scholar Jon Entine details how scientists assess the risks and benefits of chemicals. He explains how it's an irrational fear of chemicals that poses the real risk to public health.

"First published in 1974, Charles Fried's Medical Experimentation is a classic statement of the moral relationship between doctor and patient, as expressed within the concept of personal care. This concept is then tested in the context of medical experimentation and, more specifically, the randomized controlled trial (RCT). Regularly referred to as a point of departure for ethical and legal discussions of the RCT, the book has long been out of print. This new, second edition includes a general introduction by Franklin Miller and the late Alan Wertheimer, a reprint of the 1974 text, and an in-depth analysis by Harvard Law School scholars I. Glenn Cohen and D. James Greiner which discusses the extension of RTCTs to social science and public policy contexts. The volume concludes with a new essay by Charles Fried that reflects on the original text and how it applies to the contemporary landscape of medicine and medical experimentation." -- Back cover.

Lacking health insurance and diagnosed with Hodgkin's lymphoma in 2011, Speakman beat the disease as well as the massive medical debt he amassed from its treatment. He did this by publishing Unfettered, an anthology featuring short stories donated by some of the best science fiction and fantasy writers working today. The fight will not stop there. In an effort to pay forward the aid he received--and to memorialize his mother who passed away from stomach cancer in early 2016--Speakman has again collaborated with celebrated genre authors to publish Unfettered II. All proceeds from the anthology will either help eliminate medical debt for other authors or be donated to cancer research hubs around the world. Twenty original new tales comprise this amazing collection and, as the title suggests, the writers were again free to contribute whatever they wished. With the help of New York Times bestselling authors as well as talented newcomers, Speakman has taken the platform Unfettered created to not only confront medical debt but to support the battle against one of our gravest illnesses. Unfettered II is a fantastic sequel anthology but it is more than that; it is proof that we are stronger together than we are apart. After all, isn't that what genre fiction is all about?

NOW FEATURING A NEW AFTERWORD, "PANDEMIC ETHICS" From two eminent scholars comes a provocative examination of bioethics and our culture’s obsession with having it all without paying the price. Shockingly, the United States has among the lowest life expectancies and highest infant mortality rates of any high-income nation, yet, as Amy Gutmann and Jonathan D. Moreno show, we spend twice as much per capita on medical care without insuring everyone. A “remarkable, highly readable journey” (Judy Woodruff ) sure to become a classic on bioethics, Everybody Wants to Go to Heaven but Nobody Wants to Die explores the troubling contradictions between expanding medical research and neglecting human rights, from testing anthrax vaccines on children to using brain science for marketing campaigns. Providing “a clear and compassionate presentation” ( Library Journal ) of such complex topics as radical changes in doctor-patient relations, legal controversies over in vitro babies, experiments on humans, unaffordable new drugs, and limited access to hospice care, this urgent and incisive history is “required reading for anyone with a heartbeat” (Andrea Mitchell).

Psychiatrist Jeffrey Satinover examines recent research reported in medical journals (and the popular press). He finds many of these studies flawed and cites evidence that homosexuality is indeed changeable. He explains how psychology, biology, choice, and habit all interweave to produce deeply imbedded patterns of sexual behavior. The model Dr. Satinover develops is based on modern science and psychological understandings of habit, compulsion, and addiction. Homosexuality, he writes, "is one of the many forms of soul sickness that is innate to our fallen nature."

From the editor of the award-winning anthology Unfettered comes the newest installment in the science fiction and fantasy series, Unfettered III. Lacking health insurance when he was diagnosed with cancer, Shawn Speakman asked friends in the science fiction and fantasy writing community to donate short stories he could use to counter mounting medical debt. The result was Unfettered, an anthology offering tales from some of the best authors working today. Now, in Unfettered III, Speakman continues to pay forward the aid he received, raising money to combat medical debt for SF&F artists and authors. He has gathered together a great mix of new and favorite writers--free to write what they like--the result a powerful new anthology perfect for all readers. Be haunted by the chilling ghost story of Megan Lindholm. Revisit the Magicians world with Lev Grossman. Return to Osten Ard in an epic first look at Tad Williams's Empire of Grass. Callie Bates shares a heartfelt story of loss and gain. Cross the sands of the desert planet Dune with Brian Herbert and Kevin J. Anderson. Travel the Ways in a new Wheel of Time novella with Robert Jordan & Brandon Sanderson. And many more stories, all wondrous alongside beautiful art by Todd Lockwood! Katherine Arden Callie Bates Terry Brooks Delilah S. Dawson Jason Denzel David Anthony Durham Lev Grossman John Gwynne Brian Herbert & Kevin J. Anderson Robert Jordan & Brandon Sanderson Mark Lawrence Megan Lindholm (Robin Hobb) Seanan McGuire Naomi Novik Peter Orullian Cat Rambo Robert V.S. Redick Ken Scholes Scott Sigler Anna Smith Spark Shawn Speakman Anna Stephens Patrick Swenson Ramon Terrell Marc Turner Carrie Vaughn Tad Williams Deborah A. Wolf Unfettered III is sure to astound with the magic bound within its pages. All the while raising money for a charitable cause. Because protecting our artists and authors is as important as the stories they tell.

What sort of person devotes their life to the study of bugs? How do you picture your average, every-day entomologist? "I've been photographed on several occasions," writes author May Berenbaum, "and it seems that every time, photographers ask me to pose in one of three ways: seated in front of a microscope, with an insect (usually a cockroach) on my face, or with an insect net clutched in my hand." In Buzzwords , Berenbaum expertly blows away these stereotypes with short takes on all things entomological--from the story of a pet ant kept for 14 years to major motion pictures featuring cockroaches. Buzzwords showcases the Best of Berenbaum, a selection from her humor column in the American Entomologist professional journal, accompanied by a number of original pieces written for this book. "I know people are reading these columns," she notes, "because they write me letters that point out all the mistakes I've made!" The book comes in four parts: How entomologists see insects, including their view of a U.S. government plan to eradicate illicit coca fields by dropping caterpillars from airplanes. How the rest of the world sees insects, with Berenbaum's proposed classificatory scheme for placing Spider Man, Firefly, and other cartoon superheroes into well-defined taxa. How entomologists view themselves--featuring Bambi Berenbaum, a gorgeous entomologist created for an episode of TV's popular "The X-Files," whose character was inspired when the scriptwriter consulted Berenbaum's books. How entomologists see their colleagues, with various views on scholarly citation, motion sickness, and more. Along the way are some thought-provoking observations--for example, about the impact of television on public knowledge of science. In one poll, Berenbaum writes, 35% of adults said they believed that prehistoric humans coexisted with dinosaurs, a la the Flintstones. Berenbaum even takes on the controversy over alternative medicine, fearlessly purchasing Chinese medicinal insects during a professional trip to Vancouver, which also happened to be her honeymoon. "Okay, so maybe giving two talks at an International Congress of Entomology is not everybody's idea of a romantic honeymoon venue, but it seemed like a good idea at the time." Berenbaum is a noted scientist in a field that doesn't always gets the respect it deserves, but she shows us that there's a fun and even freaky side of life with insects. While working on the University of Illinois' annual Insect Fear Film Festival she received a letter from a "crush freak" who waxed lyrical about a young, sexy babe with a size 9 or 10 shoe. Berenbaum writes, "On the one hand, it's almost gratifying to think that insect pest management can arouse people's interest to such an extreme extent. On the other hand, it has convinced me not to list my shoe size in the biographical sketch of my next book." Readers will appreciate learning how the word "shloop" was introduced to the medical literature when physicians used a metal suction tip to remove a cockroach from a patient's ear canal, and how one investigator named a series of subspecies bobana, cocana, dodana, and so forth, "anticipating by 60 years the song, 'The Name Game,' by Shirley Ellis." Although you'll chuckle all the way, Berenbaum has the last laugh, giving powerful lessons in the spectacular diversity of the insect world and the nature of scientific discovery, cleverly packaged as witty observations on subjects far and wide. If you're a scientist or you like reading about science--better yet, if you've ever found a fly in your soup (or worried that you might have unknowingly just slurped one down with your tomato bisque--this book is for you.

Product Description In this thoroughly updated second edition, Judith Walzer Leavitt, a leading authority on the history of women's health issues, has collected thirty-five articles representing important scholarship in this once-neglected field. Timely and fascinating, this volume is organized chronologically and then by topic, covering studies of women and health in the colonial and revolutionary periods and the nineteenth century through the Civil War. The remainder of the book concentrates on the late nineteenth and twentieth centuries and addresses such controversial issues as body image and physical fitness, sexuality, fertility, abortion and birth control, childbirth and motherhood, mental illness, women's health care providers (midwives, nurses, physicians), and health reform and public health. Review "Superb."— Isis "Highly recommended for everyone interested in women's health."— Journal of the American Medical Women's Association "Should be on everyone's reference shelf."— Women's Studies in Indiana "Leavitt is to be commended for selecting pieces which highlight the major debates."— Women's Review of Books "It's a pleasure, as well as useful, to have such a range of excellent work in one book."— Journal of the History of Medicine "[Leavitt's] approach ensures that women's history will meet high standards and, in fact, raises the standards of historical scholarship."— Bulletin of the History of Dentistry "This anthology may be just the prescription to cure a current deficiency disease, to supply in one place the information that has been sadly lacking in historical treatments of women as patients and practitioners."— Mobius About the Author Judith Walzer Leavitt is Ruth Bleier Professor of History of Medicine, History of Science, and Women’s Studies and the associate dean of faculty at the medical school, University of Wisconsin–Madison. Her many books include The Healthiest City and Sickness and Health in America, both also available from the University of Wisconsin Press, as well as Typhoid Mary and Brought to Bed: Childbearing in America 1750–1950.

" A Courtship After Marriage places sex and marriage at the heart of modernity's making. Hirsch's innovative study of marriage-making in transnational Mexican families offers a fascinating look at the opportunities cross-border migration provides for reconstructing gender and rediscovering pleasure. This ambitious, well-crafted book speaks to anthropologists, demographers, and public health specialists, while transcending the divides between them."—Susan Greenhalgh, author of Under the Medical Gaze: Facts and Fictions of Chronic Pain "Jennifer Hirsch is one of the new wave in demographic scholars that takes culture seriously. Her book is a model of engaged, policy-relevant scholarship that achieves its warrant through deep contextualization in the everyday experience of its subjects. Beautifully written, rigorously analyzed, and almost novelistic in its nuance and detail, this study of marriage, migration, and fertility puts the people back into demography and makes one of the most powerful contributions to policy-relevant social science that I have seen in a long time. A work of beauty, sensitivity, and scholarship that sets a new standard for all that follows."—Tom Fricke, author of Himalayan Households: Tamang Demography and Domestic Processes "In this engagingly written and keenly observed ethnography of Mexican marriages in Atlanta and in small Mexican towns, Jennifer Hirsch brings love, sex and romance to Mexican immigration scholarship, and presents a compelling case for the rise of companionate marriages and ideals of spousal intimacy. This book will appeal to anyone interested in gender studies, immigrant families and the social and cultural contexts of fertility."—Pierrette Hondagneu-Sotelo, author of Domestica: Cleaning and Caring in the Shadows of Affluence "A groundbreaking study. Gracefully written, yet at the same time rigorously argued, this book reminds us of the poetry and dignity that can be found in ordinary lives and of the dreams and aspirations that sustain human agency even in the face of severe social and economic constraints. This is a major contribution to our understanding of migration, gender, sexuality, and social change in contemporary life and a model for engaged social research at its very best."—Richard Parker, author of Bodies, Pleasures and Passions "Hirsch has written a superb, insightful, and original study of Mexican migrants and the challenges of marital devotion and separation they face across time and space. Exemplary in its detail and rigor, Courtship brings us into the lives of men and women in Georgia and Jalisco, shows us the risks they take to create modern forms of intimacy, and reconceptualizes how we should view sexualized companionship, procreation, and engendered pleasures. This book will become a gold standard ethnography in medical anthropology, public health, and transnational migration studies."—Matthew C. Gutmann, author of The Romance of Democracy: Compliant Defiance in Contemporary Mexico "Hirsch’s engaging analysis of gender relations among immigrant Mexicans in Atlanta and in the Mexican community from which they come, shows how migration affects women's and men's roles, the place of sexuality in building marital intimacy, struggles over contraceptive use, and power relations in the couple. Using detailed ethnographic examples, she examines the trend toward companionate couplehood, and demonstrates both struggles and triumphs as young Mexicans and Mexican-Americans strive to create marriages that combine the strengths of traditional respect-based bonds with the advantages of new relationships built on trust."—L.A. Rebhun, author of The Heart Is Unknown Country: Love in the Changing Economy of Northeast Brazil

The discovery of how opiates such as morphine and heroin relieve pain and produce euphoria is one of the most dramatic tales of modern science. It begins in 1971 when, at the height of the undeclared war in Vietnam, Richard Nixon officially announced a war on drugs. Heroin addiction--no longer confined to urban ghettos--was causing bad public relations for the White House. The specter of young American soldiers demoralized, drugged, and committing atrocities was not the image President Nixon wished to convey as he argued for further bombings of North Vietnam. In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. Heroin or morphine molecules fit into opiate receptors much as a key fits into the ignition switch of a car--thus turning on the engine of the cell. Snyder and his students were able to show that nerve cells which possess opiate receptors are found in precisely those parts of the brain that control emotion and pain. Dr. Snyder describes the friendly yet intense competition from other researchers to expand upon this initial discovery. From the work of two Scottish investigators, Hans Kosterlitz and John Hughes, neuroscientists now know not only where opiate receptors are found in the brain but also why they are there: to serve as binding sites for an opiate-like substance produced by the brain itself--the brain's own morphine. This substance, called enkephalin, regulates pain, mood, and a host of other physiological functions. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work. We are reminded of the delicate political alliances that are forged at every level of organization, from the lab bench to the Oval Office, as the scientific community attempts to fit its needs to those of the larger society.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Gossip is no trivial matter; despite its reputation, Epstein argues, it is an eternal and necessary human enterprise. Proving that he himself is a master of the art, Epstein serves up delightful mini-biographies of the Great Gossips of the Western World, along with many choice bits from his own experience. He also makes a powerful case that gossip has morphed from its old-fashioned best--clever, mocking, a great private pleasure--to a corrosive new-school version, thanks to the reach of the mass media and the Internet. Written in his trademark erudite and witty style, Gossip captures the complexity of this immensely entertaining subject.

The tobacco controversy is usually portrayed as a battle between selfless defenders of public health and greedy merchants of death. In For Your Own Good, journalist Jacob Sullum argues that such a view conceals the true nature of the crusade for a smoke-free society. As Sullum demonstrates, this struggle is not about the behavior of corporations; it's about the behavior of individuals. It is an attempt by one group of people to impose their tastes and preferences on another. For Your Own Good shows that long before Philip Morris or R.J. Reynolds existed, tobacco's opponents condemned smoking as disgusting, immoral, addictive, unhealthy, and inconsiderate. In recent decades, they have used scientific evidence that smoking is hazardous to enlist the state in their crusade, arguing that the government has an obligation to discourage behavior that might lead to disease or injury. Given this country's tradition of limited government, however, Americans tend to be skeptical of this argument. Sullum justifies their misgivings, noting that achieving a "smoke-free society" in a nation where tens of millions choose to smoke is necessarily an exercise in tyranny.

LIFE AND ENERGY is a brilliant introduction to the chemistry of life. In this highly lucid guide to the dynamics of modern biology, Isaac Asimov deftly explores the most recent discoveries in this constantly surprising field of inquiry. In the first part, he explains the mechanics of the inanimate world, the significance of energy, work, motion, heat, and chemical reaction. He then uses these concepts in the second half to analyze and explain the latest advances in the study of enzymes, amino acids, proteins and the very processes which constitute life itself. In short, Dr. Asimov's keen examination of biology's current desire to isolate and control the very basis of life--the significance of which promises to revolutionize life itself--becomes a fascinating as well as informative excursion. Illustrated with drawings, charts and diagrams.

This book speculates about the important inventions, scientific discoveries, and political and social developments, which may occur during the coming millennium. It does this by presenting -- through the eyes of a fictitious author living in the year 3000 -- a list of the 100 men and women who have had the greatest impact on world history and on the everyday lives of individuals. The hundred persons are ranked in order of their influence. The main section of the book consists of short biographies of those 100 persons, describing what each person accomplished, and why that person is so important. Forty-five of the entries are actual historical personages. These include such well known figures as Jesus Christ, Confucius, Charles Darwin, Christopher Columbus, Albert Einstein, and George Washington. Among the fifty-five entries from the third millennium are: Sue Ellen Green (who develops a cancer vaccine); Miguel Carranza (chief founder of the United World Federation); Stella Ricardo Garcia (architect and formscaper); Mika Kivikoski (who develops the technology to control the weather); and Shu Gungwu (who finds the solution to the baffling "mind-body problem"). Other topics treated include: space travel and space colonies; medical advances (such as artificial organs, and reversible sex-change operations); arts and entertainment (including music, literature, the visual arts, and sports and games); solar power; philosophy (including political theory, epistemology, semantics, and ethics); mathematics, pollution control, robots, brainwashing; nuclear warfare; robots; and artificial intelligence. The book includes a historical chart (listing the main events of both the actual past and the projected future), a list of honorable mentions (and their accomplishments); a glossary, and an extensive index.

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics.