Here David Oshinsky tells the gripping story of the polio terror and of the intense effort to find a cure, from the March of Dimes to the discovery of the Salk and Sabin vaccines--and beyond. Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family. Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life. Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

From a Pulitzer Prize-winning historian comes a riveting history of New York's iconic public hospital that charts the turbulent rise of American medicine. Bellevue Hospital, on New York City's East Side, occupies a colorful and horrifying place in the public imagination: a den of mangled crime victims, vicious psychopaths, assorted derelicts, lunatics, and exotic-disease sufferers. In its two and a half centuries of service, there was hardly an epidemic or social catastrophe—or groundbreaking scientific advance—that did not touch Bellevue. David Oshinsky, whose last book, Polio: An American Story , was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution. From its origins in 1738 as an almshouse and pesthouse, Bellevue today is a revered public hospital bringing first-class care to anyone in need. With its diverse, ailing, and unprotesting patient population, the hospital was a natural laboratory for the nation's first clinical research. It treated tens of thousands of Civil War soldiers, launched the first civilian ambulance corps and the first nursing school for women, pioneered medical photography and psychiatric treatment, and spurred New York City to establish the country's first official Board of Health. As medical technology advanced, "voluntary" hospitals began to seek out patients willing to pay for their care. For charity cases, it was left to Bellevue to fill the void. The latter decades of the twentieth century brought rampant crime, drug addiction, and homelessness to the nation's struggling cities—problems that called a public hospital's very survival into question. It took the AIDS crisis to cement Bellevue's enduring place as New York's ultimate safety net, the iconic hospital of last resort. Lively, page-turning, fascinating, Bellevue is essential American history.

"Titillating and provocative essays from one of the freshest voices in science today -- Why do testicles hang the way they do? Is there an adaptive function to the female orgasm? What does it feel like to want to kill yourself? Does "free will" really exist? And why is the penis shaped like that anyway? In Why Is the Penis Shaped Like That?, the research psychologist and award-winning columnist Jesse Bering features more than thirty of his most popular essays from Scientific American and Slate, as well as two new pieces, that take readers on a bold and captivating journey through some of the most taboo issues related to evolution and human behavior. Exploring the history of cannibalism, the neurology of people who are sexually attracted to animals, the evolution of human body fluids, the science of homosexuality, and serious questions about life and death, Bering astutely covers a generous expanse of our kaleidoscope of quirks and origins. With his characteristic irreverence and trademark cheekiness, Bering leaves no topic unturned or curiosity unexamined, and he does it all with an audaciously original voice. Whether you are interested in the psychological history behind the many facets of sexual desire or the evolutionary patterns that have dictated our current mystique and phallic physique, Why Is the Penis Shaped Like That? is bound to create lively discussion and debate for years to come"--

"Mitch Albom has done it again with this moving memoir of love and loss. You can't help but fall for Chika. A page-turner that will no doubt become a classic." --Mary Karr, author of The Liars' Club and The Art of Memoir From the #1 New York Times bestselling author of Tuesdays With Morrie comes Mitch Albom's most personal story to date: an intimate and heartwarming memoir about what it means to be a family and the young Haitian orphan whose short life would forever change his heart. Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the forty-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. Chika's arrival makes a quick impression. Brave and self-assured, even as a three-year-old, she delights the other kids and teachers. But at age five, Chika is suddenly diagnosed with something a doctor there says, "No one in Haiti can help you with." Mitch and Janine bring Chika to Detroit, hopeful that American medical care can soon return her to her homeland. Instead, Chika becomes a permanent part of their household, and their lives, as they embark on a two-year, around-the-world journey to find a cure. As Chika's boundless optimism and humor teach Mitch the joys of caring for a child, he learns that a relationship built on love, no matter what blows it takes, can never be lost. Told in hindsight, and through illuminating conversations with Chika herself, this is Albom at his most poignant and vulnerable. Finding Chika is a celebration of a girl, her adoptive guardians, and the incredible bond they formed--a devastatingly beautiful portrait of what it means to be a family, regardless of how it is made.

"For as long as he has served at the highest levels of business and government, Vice President Dick Cheney has also been one of the world's most prominent heart patients. Now, for the first time ever, Cheney, together with his longtime cardiologist Jonathan Reiner, MD, shares the very personal story of his courageous thirty-five-year battle with heart disease, from his first heart attack in 1978 to the heart transplant he received in 2012. In 1978, when Cheney suffered his first heart attack, he receivedessentially the same treatment as President Eisenhower had in 1955. Since then, cardiac medicine has evolved in extraordinary ways, and Cheney has benefited from nearly every medical and technological breakthrough along the way. At each juncture, when Cheney faced a new health challenge, the technology was one step ahead of his disease. In many ways, Cheney's story is the story of the evolution of modern cardiac care. Heart is the riveting, singular memoir of both doctor and patient, tracking their relationship as it unfolds over many years and crises. Like no US politician has before him, Cheney opens up about his health struggles, sharing harrowing, never-before-told stories about the challenges he faced during a perilous time in our nation's history. Dr. Reiner provides his perspective on Cheney's case and also gives readers a fascinating glimpse into his own education as a doctor. He masterfully chronicles the important discoveries, radical innovations, and cutting-edge science that have changed the face of medicine and saved countless lives. Powerfully braiding science with story and the personal with the political, Heart is a sweeping, inspiring, and ultimately optimistic book that will give hope to the millions of Americans affected by heart disease"--

This tale of two families is set on a grand scale, as James Thomas Flexner brings his talents to bear on his own noteworthy heritage. An American Saga is an historical narrative, grounded on documentary sources, which ends with the marriage of Helen Thomas and Simon Flexner. The account deals equally with the lives and the backgrounds of husband and wife, the author's parents. Simon Flexner was the famous medical investigator, discoverer of the "Flexner vacillus" and the "Flexner serum," who became the creating director of the Rockefeller Institute for Medical Research (now Rockefeller University) and eventually acknowledged leader of American medical science. The Kentucky-born son of impoverished German Jewish immigrants, he grew up in penury. As he never completed the eighth grade, he was almost completely self-educated when he appeared at the Johns Hopkins University before its celebrated medical school had been founded. Almost instantly he began making the discoveries that soon made him the leading younger medical scientist in the United States.

The discovery of how opiates such as morphine and heroin relieve pain and produce euphoria is one of the most dramatic tales of modern science. It begins in 1971 when, at the height of the undeclared war in Vietnam, Richard Nixon officially announced a war on drugs. Heroin addiction--no longer confined to urban ghettos--was causing bad public relations for the White House. The specter of young American soldiers demoralized, drugged, and committing atrocities was not the image President Nixon wished to convey as he argued for further bombings of North Vietnam. In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. Heroin or morphine molecules fit into opiate receptors much as a key fits into the ignition switch of a car--thus turning on the engine of the cell. Snyder and his students were able to show that nerve cells which possess opiate receptors are found in precisely those parts of the brain that control emotion and pain. Dr. Snyder describes the friendly yet intense competition from other researchers to expand upon this initial discovery. From the work of two Scottish investigators, Hans Kosterlitz and John Hughes, neuroscientists now know not only where opiate receptors are found in the brain but also why they are there: to serve as binding sites for an opiate-like substance produced by the brain itself--the brain's own morphine. This substance, called enkephalin, regulates pain, mood, and a host of other physiological functions. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work. We are reminded of the delicate political alliances that are forged at every level of organization, from the lab bench to the Oval Office, as the scientific community attempts to fit its needs to those of the larger society.

The man in the street would not, perhaps, recognize all the names of the brilliant scientists whose careers and personalities animate this book, but doctors know them. Morgan, who founded the first medical school in American and, fighting beside Washington, was ruined b the petty politics of the Revolution; McDowell, who, although on the fringe of the wilderness, dared the operation that prepared the way for all abdominal surgery; Rush, the equivocal personality who, for better or worse, dominated American medicine for more than fifty years; Beaumont, who, saving a life, won a living laboratory; Drake, who brought modern medicine to the New West; Long and Morton, who banished pain from surgery and earned it for themselves these men are honored in their profession today.

Although organ transplantation is the preeminent medical miracle of the last quarter of a century, Many Sleepless Nights is the first book to go beyond the headlines and describe the patients who have embraced this last chance to hold on to life, the intricate medical procedures that can save them, the surgeons and nurses who work in this emotionally charged world, and the ethics which complicate this miracle high-tech therapy. Lee Gutkind was granted unconditional access to the world's largest transplant center - the University of Pittsburgh's Presbyterian-University and Children's hospitals, where there is an organ transplant every eight hours, 365 days per year. For four years he immersed himself in the frantic night-and-day world of transplantation, living side by side with transplant candidates and recipients, jetting though the night with organ procurement teams, monitoring patients with surgeons and nurses, observing in the operating room, participating in the ethical and psychosocial evaluations of prospective patients which help to determine who will receive scarce organs. During his four years at Presbyterian and Children's Hospitals, Gutkind established close relationships with many patients, and his portrayal of them, living and sometimes dying under unbelievable stress, is a moving and dramatic statement about the capacity of human beings to endure. Many Sleepless Nights also outlines the history of organ transplantation and tells the story of the large and complex medical teams behind the operation. It captures the tension of the search for viable organs; the pressure decisions about which patients, among many, will receive them; and the surgery itself.Its vivid portrayal of the transplant pioneer Thomas Starzl - a man obsessed with saving lives - shows how a major innovator in American medicine functions during days and nights of extreme pressure.

It has been said that the only warriors who do not suffer after combat are those who were killed. I cannot attest to that for all battle tested warriors but I certainly can for one---me. Some years ago a young, 13 year old eighth grade student from the Fairfield, Iowa Middle School once asked me, "Were you wounded in the war? I had been invited to speak in Mrs. Broz's class for many years to talk about my wartime experiences. I had been asked and answered many questions but this one was different. I paused, thought deeply and quickly, and replied. "Yes I was wounded, seriously wounded but not a wound that anyone could see and fix." His question gave me pause to quickly think about warriors in all the wars that have been fought, including mine, whose wounds were unseen, untreated and debilitating even though no blood was shed. I spent a sleepless night wondering if my answer had satisfied him...or me. What was there about my military service that left me so hopeless and so helpless when I returned home to civilian life? Was it me? The military itself? The combat? This is what I recalled; perhaps the answers would come as I wrote my experiences down. "I've been practicing Transcendental Meditation for 40 years. It's a great tool for reducing stress ... especially the stress our men and women of the Armed Forces are going through now." --Clint Eastwood, Academy Award-Winning Film Director "Stress causes, anxiety, depression, and violent behavior. Transcendental Meditation is a remarkable process for reducing stress-it can help people live a long and better life." --Mehemet Oz, MD, America's Doctor "In this riveting memoir, a true American hero describes how Transcendental Meditation changed his life for good. A must-read for those struggling with the aftershocks of combat, and their loved ones." --Norman Rosenthal, M.D. Author of Transcendence: Healing and Transformation Through Meditation "The hidden cost of war includes long-term pain and suffering for may veterans and their families. This wonderful book shows how meditation can be a practical, simple, and effective way for our returning warriors to find peace." --Professor Linda Bilmes, Harvard University, co-author of The Three Trillion Dollar War "The Resilient warrior is a riveting read. What is especially impressive is how Jerry Yellin conflates his own war and PTSD experiences, and those experiences of other veterans, with the powerful compelling evidence of the benefits of using meditation as a means to overcome this disorder. I highly recommend this book to anyone seeking relief from stress, regardless of the source of the trauma." --Donald Mikkleson, Vietnam Veteran "My son, Dory, was an eight-year Army veteran who committed suicide early this year and I have suffered terribly. On a really bad day, a few weeks after Dory's death, Jerry Yellin suggested that I read The Resilient Warrior and learn to meditate. Since starting to meditate I can feel the stress leaving me, and my days and nights are getting a little better day-by-day, week-by-week. I strongly recommend Jerry's book to veterans and families of veterans, and anyone who is looking for a way of the nightmare of PTSD." --Lin Klock, Vero Beach, Florida Author Jerry Yellin Jerry was a WW 2 fighter pilot from Hillside, NJ. He flew P-51's over Japan from Iwo Jima. Married to Helene for 60 years, they have four sons and six grandchildren. Jerry is the author of the award winning historical fiction book The Blackened Canteen and his memoir Of War and Weddings . The soldier above all other people prays for peace, for he must suffer and bear the deepest wounds and scars of war." --General Douglas Macarthur

"Here is a singular story of survival, an earthly miracle wrought by family devotion, gardens, horses, guts. A compelling read."—Carolyn Heilbrun In July 1998, when Maxine Kumin's horse bolted at a carriage-driving clinic, she was not expected to live. Yet, less than a year later, her progress pronounced a miracle by her doctors, she was at work on this journal of her astonishing recovery. She tells of her time "inside the halo," the near-medieval device that kept her head immobile during weeks of intensive care and rehabilitation, of the lasting "rehab" friendships, and of the loving family who always believed she would heal. "[S]he resonates wisdom while announcing a triumph of body and soul."—Anne Roiphe, New York Times Book Review "Maxine Kumin brings the sensitivity and imagination of a poet to her extraordinary ordeal."—Richard Selzer, author of Mortal Lessons: Notes on the Art of Surgery "From a singular experience she has created a lesson that is universal, which, it seems to me, is the essence of being a poet."—Abraham Verghese, author of The Tennis Partner

"I have been a Jew during Fascism, a bourgeois under Communism, a rebel defeated in an uprising, a refugee among the free, and a have-not amid plenty. This book contains over 60 stories that range from my youth in Hungary, the ordeal of a death march and concentration camps, the oppression of the Communist dictatorship, the promise and defeat of the Hungarian Revolution and, finally, my American years"--Preminary pages