A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” ( American Scientist ), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.

Shortly before his 44th birthday, John Diamond received a call from the doctor who had removed a lump from his neck. Having been assured for the previous 2 years that this was a benign cyst, Diamond was told that it was, in fact, cancerous. Suddenly, this man who'd until this point been one of the world's greatest hypochondriacs, was genuinely faced with mortality. And what he saw scared the wits out of him. Out of necessity, he wrote about his feelings in his TIMES column and the response was staggering. Mailbag followed Diamond's story of life with, and without, a lump - the humiliations, the ridiculous bits, the funny bits, the tearful bits. It's compelling, profound, witty, in the mould of THE DIVING BELL & THE BUTTERFLY.

Joanne Limburg suffers from Obsessive-Compulsive Disorder: she thinks things she doesn't want to think, and she does things she doesn't want to do. As a small child, she would chew her hair all day and lie awake at night wondering if heaven had a ceiling; a few years later, when she should have been doing her homework, she was pacing her bedroom, agonising about the unfairness of life as a woman, and the shortness of her legs. By the time she was an adult, obsessive thoughts and compulsive behaviours had come to dominate her life. She knew that something was wrong with her, but it would take many years before she understood what that something was. "The Woman Who Thought Too Much" follows Limburg's quest to understand her predicament and to manage her symptoms, taking the reader with her on a long, twisted journey through consulting rooms, libraries and internet sites, as she seeks to discover all she can about rumination, scrupulosity, avoidance, thought-action fusion, fixed-action patterns, anal fixations, schemas, basal ganglia, tics and synapses. On the way, she encounters competing interpretations of her condition, as offered by psychoanalysts, neuropsychiatrists and cognitive psychologists, and does her best to come to terms with an illness which turns out to be both common, and even - sometimes - treatable. This candid, moving and beautifully written memoir is a sometimes shocking, often sad, and yet also humorous revelation of what it is like to live with so debilitating a condition. It is also an exploration of the inner world of a poet and an intense evocation of the persistence and courage of the human spirit in the face of mental illness.