Joining the ranks of modern myth busters, Dr. Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria. So why does disease exist? Moalem proposes that most common ailments--diabetes, hemochromatosis, cystic fibrosis, sickle cell anemia--came into existence for very good reasons. At some point they helped our ancestors survive some grand challenge to their existence. Examining the evolution of man, Moalem reveals the role genetic and cultural differences have played in the health and well-being of various races, including their susceptibility to disease. With mesmerizing insight, Moalem offers groundbreaking insight into: - How diabetes may be a biproduct of a mechanism that helped humans survive the Ice Age - Why African Americans living in the north might suffer from vitamin D deficiencies, - Why Asians can't drink as much alcohol as Europeans Revelatory, utterly engaging, and timely--Moalem ponders strongN1, the emerging Avian Flu virus--Why Redheads Feel More Pain and Asians Can't Drink will irrevocably change the way we think about our bodies and ourselves.

Carl Zimmer tells the story of the theory of evolution from Darwin's journey on the Beagle to the controversies of modern evolutionary theory the understanding of the lethal resurgence of antibiotic resistant diseases and the wave of species extinctions that face us today. The result is a wonderfully accessible account of a remarkable scientific journey from the emergence to the triumph of an idea.

Addresses the fundamental question of what it means to be alive from the perspective of a microbe, E. coli, that exists within all human beings, examining the germ's evolution and its important role in the history of biology.

Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured.Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation.This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.

In 2013 Stephen Meyer's book Darwin's Doubt: The Explosive Origin of Animal Life and the Case for Intelligent Design became a national bestseller, provoking a wide-ranging debate about the adequacy of Darwinian theory to explain life's history. In Debating Darwin's Doubt: A Scientific Controversy that Can No Longer Be Denied , leading scholars in the intelligent design community respond to critiques of Meyer's book and show that the core challenge posed by Meyer remains unanswered: Where did the influx of information essential to the creation of new body plans come from? In addition to ten chapters by Stephen Meyer, Debating Darwin's Doubt also includes contributions from biologists Richard Sternberg, Douglas Axe, and Ann Gauger; philosopher of biology Paul Nelson; mathematicians William Dembski and David Berlinski; and Center for Science and Culture research coordinator Casey Luskin. In forty-four chapters, these contributing authors explore topics such as orphan genes, cladistics, small shelly fossils, protein evolution, the length of the Cambrian explosion, the God-of-the-Gaps objection to intelligent design, and criticisms raised by proponents of theistic evolution. Anyone who wants to understand the cutting-edge of current scientific debates over modern Darwinian theory needs to read this book.

Nobelist Eric Kandel's account of how his personal quest to understand memory intersected with the emergence of a new science. In Search of Memory relates the astonishing story of how four different and distinct disciplinesbehaviorist psychology, cognitive psychology, neuroscience, and molecular biologyconverged into a powerful new science of mind. Through its profound insights into thought, perception, action, recollection, and mental illness, this new science is revolutionizing our understanding of learning and memory while simultaneously showing great promise for more effective healing. The narrative follows Eric R. Kandel through the last five decades, focusing on Vienna, where he became fascinated with memory. With intrepid scientific ardor, Kandel was captivated first by history and psychoanalysis, then by neurobiology, and finally by the biological processes of memory. His resulting, multifaceted perspective was the foundation for his path-breaking research that will continue to dominate modern thoughtnot only in science but in culture at large. 50 illustrations.

Astrophysicist and author Mario Livio investigates perhaps the most human of all our characteristics—curiosity—in this “lively, expert, and definitely not dumbed-down account” ( Kirkus Reviews ) as he explores our innate desire to know why . Experiments demonstrate that people are more distracted when they overhear a phone conversation—where they can know only one side of the dialogue—than when they overhear two people talking and know both sides. Why does half a conversation make us more curious than a whole conversation? “Have you ever wondered why we wonder why? Mario Livio has, and he takes you on a fascinating quest to understand the origin and mechanisms of our curiosity. I thoroughly recommend it.” (Adam Riess, Nobel Prize Winner in Physics, 2011). Curiosity is not only at the heart of mystery and suspense novels, it is also essential to other creative endeavors, from painting to sculpture to music. It is the principal driver of basic scientific research. Even so, there is still no definitive scientific consensus about why we humans are so curious, or about the mechanisms in our brain that are responsible for curiosity. In the ever-fascinating Why? Livio interviewed scientists in several fields to explore the nature of curiosity. He examined the lives of two of history’s most curious geniuses, Leonardo da Vinci and Richard Feynman. He also talked to people with boundless curiosity: a superstar rock guitarist who is also an astrophysicist; an astronaut with degrees in computer science, biology, literature, and medicine. What drives these people to be curious about so many subjects? An astrophysicist who has written about mathematics, biology, and now psychology and neuroscience, Livio has firsthand knowledge of his subject which he explores in a lucid, entertaining way that will captivate anyone who is curious about curiosity.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

How the simulation and visualization technologies so pervasive in science, engineering, and design have changed our way of seeing the world. Over the past twenty years, the technologies of simulation and visualization have changed our ways of looking at the world. In Simulation and Its Discontents , Sherry Turkle examines the now dominant medium of our working lives and finds that simulation has become its own sensibility. We hear it in Turkle's description of architecture students who no longer design with a pencil, of science and engineering students who admit that computer models seem more “real” than experiments in physical laboratories. Echoing architect Louis Kahn's famous question, “What does a brick want?”, Turkle asks, “What does simulation want?” Simulations want, even demand, immersion, and the benefits are clear. Architects create buildings unimaginable before virtual design; scientists determine the structure of molecules by manipulating them in virtual space; physicians practice anatomy on digitized humans. But immersed in simulation, we are vulnerable. There are losses as well as gains. Older scientists describe a younger generation as “drunk with code.” Young scientists, engineers, and designers, full citizens of the virtual, scramble to capture their mentors' tacit knowledge of buildings and bodies. From both sides of a generational divide, there is anxiety that in simulation, something important is slipping away. Turkle's examination of simulation over the past twenty years is followed by four in-depth investigations of contemporary simulation culture: space exploration, oceanography, architecture, and biology.

In The Logic of Life François Jacob looks at the way our understanding of biology has changed since the sixteenth century. He describes four fundamental turning points in the perception of the structure of living things: the discoveries of the functions of organs, cells, chromosomes and genes, and DNA.

This book explores changing American views of race mixing in the twentieth century, showing how new scientific ideas transformed accepted notions of race and how those ideas played out on college campuses in the 1960s. In the 1930s, it was not unusual for medical experts to caution against miscegenation, or race mixing, espousing the common opinion that it would produce biologically dysfunctional offspring. By the 1960s the scientific community roundly refuted this theory. The author traces this revolutionary shift in scientific thought, explaining how developments in modern population biology, genetics, and anthropology proved that opposition to race mixing was a social prejudice with no justification in scientific knowledge. In the 1960s, this new knowledge helped to change attitudes towards race and discrimination, especially among college students. Their embrace of social integration caused tension on campuses across the country. Students rebelled against administrative interference in their private lives, and university regulations against interracial dating became a flashpoint in the campus revolts that revolutionized American educational institutions. The author's provocative study is a personal one, featuring interviews with mixed-race couples and stories from the author's student years at the University of Pittsburgh. As such, this book offers a unique perspective on how contentious debates taking place on college campuses reflected shifts in race relations in the larger society. -- from Back Cover

This collection of essays explains and encourages new reflection on Paul Rabinows pioneering project to anthropologize the West. His goal is to exoticize the Western constitution of reality, emphasize those domains most taken for granted as universal, and show how their claims to truth are linked to particular social practices, hence becoming effective social forces. He has recently begun to focus on the core of Western rationality, in particular the practices of molecular biology as they apply to our understanding of human nature. This book moves in new directions by posing questions about how scientific practice can be understood in terms of ethics as well as in terms of power.The topics include how French socialist urban planning in the 1930s engineered the transition from city planning to life planning; how the discursive and nondiscursive practices of the Human Genome Project and biotechnology have refigured life, labor, and language; and how a debate over patenting cell lines and over the dignity of life required secular courts to invoke medieval notions of the sacred. Building on an ethnographic study of the invention of the polymerase chain reaction--which enables the rapid production of specific sequences of DNA in millions of copies Rabinow, in the final essay, reflects in dialogue with biochemist Tom White on the place of science in modernity, on science as a vocation, and on the differences between the human and natural sciences.

Explores the complex factors and long line of "ancestors" that have contributed to human sexuality and human sexual behavior

This book is the first devoted to modern biology s innovators and iconoclasts: men and women who challenged prevailing notions in their fields. Some of these scientists were Nobel Prize winners, some were considered cranks or gadflies, some were in fact wrong. The stories of these stubborn dissenters are individually fascinating. Taken together, they provide unparalleled insights into the role of dissent and controversy in science and especially the growth of biological thought over the past century. Each of the book s nineteen specially commissioned chapters offers a detailed portrait of the intellectual rebellion of a particular scientist working in a major area of biology--genetics, evolution, embryology, ecology, biochemistry, neurobiology, and virology as well as others. An introduction by the volume s editors and an epilogue by R. C. Lewontin draw connections among the case studies and illuminate the nonconforming scientist s crucial function of disturbing the comfort of those in the majority. By focusing on the dynamics and impact of dissent rather than on winners who are credited with scientific advances, the book presents a refreshingly original perspective on the history of the life sciences. Scientists featured in this volume: Alfred Russel Wallace Hans Driesch Wilhelm Johannsen Raymond Arthur Dart C. D. Darlington Richard Goldschmidt Barbara McClintock Oswald T. Avery Roger Sperry Leon Croizat Vero Copner Wynne-Edwards Peter Mitchell Howard Temin Motoo Kimura William D. Hamilton Carl Woese Stephen Jay Gould Thelma Rowell Daniel S. Simberloff "

"Is life different from the non-living? If so, how? And how, in that case, does biology, as the study of living things, differ from other sciences? These questions lie at the heart of The Philosophy of Biology, and are traced through an exploration of episodes in the history of biology and philosophy. The book begins with Aristotle, then moves on to Descartes, comparing his position with that of Harvey. From the eighteenth century, the authors consider Buffon and Kant. From the nineteenth century, the authors examine the Cuvier-Geoffroy debate, pre-Darwinian geology and natural theology, Darwin, and the transition from Darwin to the revival of Mendelism. Two chapters on the twentieth century deal with the Modern Evolutionary Synthesis and such questions as the species problem, the reducibility or otherwise of biology to physics and chemistry, and the problem of biological explanation in terms of function and teleology. The final chapters reflect on the question of human nature and the implications of the philosophy of biology for the philosophy of science in general."--Jacket

The stories of nineteen scientists--some famous, some forgotten--who stubbornly challenged assumptions and icons in the life sciences This book is the first devoted to modern biology's innovators and iconoclasts: men and women who challenged prevailing notions in their fields. Some of these scientists were Nobel Prize winners, some were considered cranks or gadflies, some were in fact wrong. The stories of these stubborn dissenters are individually fascinating. Taken together, they provide unparalleled insights into the role of dissent and controversy in science and especially the growth of biological thought over the past century. Each of the book's nineteen specially commissioned chapters offers a detailed portrait of the intellectual rebellion of a particular scientist working in a major area of biology--genetics, evolution, embryology, ecology, biochemistry, neurobiology, and virology as well as others. An introduction by the volume's editors and an epilogue by R. C. Lewontin draw connections among the case studies and illuminate the nonconforming scientist's crucial function of disturbing the comfort of those in the majority. By focusing on the dynamics and impact of dissent rather than on "winners" who are credited with scientific advances, the book presents a refreshingly original perspective on the history of the life sciences. Scientists featured in this volume: Alfred Russel Wallace Hans Driesch Wilhelm Johannsen Raymond Arthur Dart C. D. Darlington Richard Goldschmidt Barbara McClintock Oswald T. Avery Roger Sperry Leon Croizat Vero Copner Wynne-Edwards Peter Mitchell Howard Temin Motoo Kimura William D. Hamilton Carl Woese Stephen Jay Gould Thelma Rowell Daniel S. Simberloff

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Embark on an intellectual adventure with Puzzles and Paradoxes, a captivating book that presents 33 thought-provoking questions spanning history, the physical world, biology, philosophy, specific events, and miscellaneous topics, enticing readers to unravel mysteries and seek profound understanding. From the fall of Rome to the Golden Age of Greece, from the enigmas of the mind-body problem to the origins of life on Earth, from free will to the problem of evil, and from the invention of spectacles to the Monty Hall Problem and the Voynich Manuscript, this compelling collection explores diverse realms of knowledge, offering possible answers that inspire contemplation and ignite the joy of intellectual discovery.

Singer ( History of technology ) published this book in 1931 with Abelard-Schuman. He surveys the development of the science of biology from its early beginnings, circa 400 BC to the early 20th century. Annotation copyright Book News, Inc. Portland, Or.