The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics.

In this ground breaking work, Langs turns to evolutionary biology, the fundamental theory of biological sciences, to derive a set of principles that deeply reform psychoanalytic theory and practice. In doing so he makes a profound announcement of the new field of Evolutionary Psychoanalysis and continues his long-standing project of expanding classical psychoanalysis by forging connections with other biological sciences.

In this remarkable book by one of the great psychologists and neurologists of the early twentieth century, Kurt Goldstein presents a summation of his “holistic” theory of the human organism. In the course of his studies on brain-damaged soldiers during the First World War, Goldstein became aware of the failure of contemporary biology and medicine to genuinely understand both the impact of such injuries and the astonishing adjustments that patients made to them. He challenged reductivist approaches that dealt with “localized” symptoms, insisting instead that an organism be analyzed in terms of the totality of its behavior and interaction with its surrounding milieu. He was especially concerned with the breakdown of organization and the failure of central cerebral controls that take place in catastrophic responses to situations such as physical or mental illness. But Goldstein was equally attuned to the amazing powers of the organism to readjust to such devastating losses, if only by withdrawal to a more limited range of activity that it could manage by a redistribution of its reduced energies, thus reclaiming as much wholeness as new circumstances allowed. Goldstein’s concepts in The Organism have had a major impact on philosophical and psychological thought throughout this century, as can be seen in the work of Maurice Merleau-Ponty, Georges Canguilhem, Ernst Cassirer, Ludwig Binswanger, and Roman Jakobson, not to mention the wide-ranging field of Gestalt psychology.

Partial table of contents: NEUROPEPTIDES AND THE STRESS RESPONSE. Brain Corticotropin Releasing Factor and Development (T. Insel, et al.). Opioids, Stress, and the Developing Brain (I. Zagon & P. McLaughlin). THE ADRENAL MEDULLA AND STRESS. Catecholamines and Stress in the Newborn (T. Slotkin & F. Seidler). Endogeneous Neuropeptides Maintain Adrenal Catecholamine Output during Stress (B. Livett, et al.). IMMUNOBIOLOGY OF STRESS. Shock Induced Immunosuppression: Naltrexone Sensitive and Insensitive Parameters (J. Cunnick, et al.). Regulation of Interleukin-2 Expression by Dexamethasone in a Mouse T Cell Line (B. Sorg, et al.). PHYSICAL CONSEQUENCES OF STRESS. Enzymatic and Morphological Adaptation to Physical Exercise in Young Middle Aged, and Old Mice: A Model for Physical Stress (A. Reznick, et al.). Gastric Erosion Formation by Stress: Brain Stem Mechanisms (H. Weiner, et al.). STRESS AND BEHAVIOR. Information-Induced Stress in Humans (S. Breznitz). Affect Specific Retrieval from Archival Memory (H. Weingartner, et al.). Index.

Mental Chronometry (MC) comprises a variety of techniques for measuring the speed with which the brain processes information. First developed in mid-1800, MC was subsequently eclipsed by more complex and practically useful types of psychometric tests stemming from Alfred Binet. This class of mental tests, however, has no true metric relating the test scores to any specific properties of the brain per se. The scores merely represent an ordinal scale, only ranking individuals according to their overall performance on a variety of complex mental tasks. The resulting scores represent no more than ranks rather than being a true metrical scale of any specific dimension of brain function. Such an ordinal scale, which merely ranks individuals in some defined population, possesses no true scale properties, possessing neither a true zero or equal intervals throughout the scale. This deficiency obstructs the development of a true natural science of mental ability. The present burgeoning interest in understanding individual differences in mental abilities in terms of the natural sciences, biology and the brain sciences in particular, demands direct measures that functionally link brain and behavior. One such natural ratio scale is time itself - the time it takes the brain to perform some elementary cognitive task, measured in milliseconds. After more than 25 years researching MC, Jensen here presents results on an absolute scale showing times for intake of visual and auditory information, for accessing short-term and long-term memory, and other cognitive skills, as a function of age, at yearly intervals from 3 to 80 years. The possible uses of MC in neurological diagnosis and the monitoring of drug effects on cognition, the chronometric study of special time-sensitive talents such as musical performance, and presents a theory of general intelligence, or g, as a function of the rate of oscillation of neural action potentials as