Humanity has always been intrigued by the timeless question: Where did we come from? In 1974, the discovery of the fossilised bones of a three-million-year-old female dubbed 'Lucy' captured the world's attention. This nearly complete skeleton of an early human ancestor not only triggered widespread interest in our human origins but also prompted a thorough re-evaluation of established scientific doctrines. Today, hardly a month goes by without news of significant discoveries that are changing our understanding of human origins at what seems like the speed of lightning. But what does all this new knowledge about our species mean? That's exactly what acclaimed science writer Carl Zimmer tackles in this accessible, up-to-the-minute guide to human origins. Zimmer offers an entertaining and illuminating journey through our ancestry - beginning sixty-five million years ago with the first primates and ending today, as we enter a new phase of evolution. From ancient fossils unearthed in the Sahara Desert to the analysis of DNA by robots at the National Human Genome Research Institute in suburban Maryland, Zimmer weaves together the varied clues about our human ancestry in an entertaining, informative and highly readable volume that will appeal to expert and general reader alike.

This enticing collection is as devoted to the profound power of figures of speech as any oration of old Hellas. Metaphor reigns as we encounter the identification of our Earth as a Single, integrative organism, a tale told in image and passion. The discoveries and conjectures upon which this grand view rest are here as well. I have enjoyed these two dozen pieces hugely. No family tree of animal life but must somewhere disclose a cousinly infolding. We are compact of life past, and the looped handing down is more complex than the Mendel-Morgan dance of chromosomes and genes. That dance is essential, certainly, but it is the vital editing of an epic and many-rooted work, a book more like the Bible than like one great artists Remembrance of Things Past. We follow a few old shelves of bound DNA, not just a single book. Our major biochemical package for oxidative metabolism was de scribed in a small DNA manual, somehow engulfed to become an or ganelle within a lucky ancient ancestral anaerobe, and passed ever since viii FOREWORD from mother to offspring outside of the chromosome shuffie. The sperm do carry half the compact genetic message of the human DNA, but they are too small to transfer this equally essential symbiotic one that comes down from the mothers, within roomy egg after roomy egg.

In The Logic of Life François Jacob looks at the way our understanding of biology has changed since the sixteenth century. He describes four fundamental turning points in the perception of the structure of living things: the discoveries of the functions of organs, cells, chromosomes and genes, and DNA.

This book commemorates the eclectic intellectual life of scientist and artist Walter Gilbert. It presents all of his most influential works throughout his scientific career. His scientific explorations covered a broad spectrum of fields: theoretical physics; molecular biology, from finding messenger RNA to elucidating the regulation of the lac operon to understanding DNA replication; gene evolution and origin of life; genomics; bioinformatics; and beyond. He created widely used concepts such as 'Exon', 'Intron' and 'RNA World'. Eleven reflective essays by Gilbert are included for the first time, discussing both his scientific studies and anecdotes from his own life. These firsthand accounts record the historical and intellectual contexts for his most monumental scientific discoveries, including his Nobel Prize-winning sequencing method. Memorial chapters, contributed by Gilbert Laboratory alumni, describe the passion, ambition, and efforts of Gilbert and several generations of young scientists under his leadership. Finally, the book collects a few fine pieces of artwork created by Gilbert in recent years. It documents a life of genius and creativity that could inspire others for years to come.