The exclusive, first-hand, behind-the-scenes story of how Pfizer raced to create the first Covid-19 vaccine, told by Pfizer's CEO Dr. Albert Bourla A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made "the impossible possible"--creating, testing, and manufacturing a safe and effective Covid-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer, under the enormous strains of the global pandemic, overcame a series of crises that were compounded by social and political unrest, and reveals the doubts, decisions, obstacles, and failures they encountered. As Dr. Bourla makes clear, Pfizer's success wasn't due to luck; it was because of preparation driven by four simple values--Courage, Excellence, Equity, and Joy. Moonshot is a story of leadership under the most unprecedented circumstances--how Dr. Bourla, a Greek immigrant, a child of Holocaust survivors, and a veterinarian, became the head of one of the world's largest corporations and initiated a dramatic transformation of the organization just before a global health crisis would serve to test the organization, its scientists and its leader, like never before. Moonshot describes best practices that can be used to address the multiple, unprecedented challenges our world faces, reveals Pfizer's implementation of scientific breakthroughs at a record-breaking pace, and offers leadership lessons that can help anyone successfully manage their own seemingly unsolvable problems. As Dr. Bourla explains, "I am sharing the story of our moonshot--the challenges we faced, the lessons we learned, and the core values that allowed us to make it happen--in hopes that it might inspire and inform your own moonshot, whatever that may be."

The competition for limited health care resources is intensifying. We urgently need an acceptable method for deciding how they should be allocated. But the goods that health care produces are of very different kinds. Health care can extend the lives of children and of older people. It can make it possible for a person to walk, when without health care that person would be permanently bedridden; and it can reduce the pain and distress of people who are terminally ill. How can we possibly decide which of these - and many more - diverse achievements of health care are more deserving than others? We need a common unit by which we might be able to measure these very different goods. The Quality-Adjusted Life Year, or QALY, is the most developed proposal for such a unit of measure. In this book a distinguished team of ethicists and economists defend the core of the QALY proposal: that health care resources should be used so as to produce more years of life, of the highest possible quality. This leads to a discussion of such fundamental questions as whether all lives are of equal value, whether health care should be allocated on the basis of need and whether the QALY approach incorporates an adequate account of fairness or justice. The result is the most thorough account yet of the ethical issues raised by the use of the QALY as a basis for allocating health care resources.

A vast amount of research linking stress and health has been done throughout the last decade in the fields of heart disease, cancer, chronic fatigue syndrome, and many other potentially stress-related illnesses. The Handbook of Stress, Medicine, and Health brings together the most distinguished authors in the world and presents the role of stress in illness and health. This exciting book sets the agenda for the new field of stress medicine. Filled with valuable practical information, this comprehensive resource investigates the health effects of life events and work. The physiological impact of critical life changes is discussed, and general occupational stress as well as the stress, from exposure on the job to HIV and AIDS are examined. The relationship between personality types, behavior patterns, and the risk of disease is explored. The guide also reviews the importance of social support during times of illness. It details how families can help alleviate or exacerbate stress. The Handbook offers guidelines for preventing and treating stress-related illnesses and includes insightful steps for coping with the stress of cancer. The Handbook of Stress, Medicine, and Health provides-under one cover-an overview of research, important information that can readily be used, plus recommendations for the direction of future study.

This issues-based reference work (available in both print and electronic formats) shines a spotlight on health care policy and practice in the United States. Impassioned debates about the best solutions to health care in America have perennially erupted among politicians, scholars of public policy, medical professionals, and the general public. The fight over the Health Care Reform Act of 2010 brought to light a multitude of fears, challenges, obstacles, and passions that often had the effect of complicating rather than clarifying the debate. The discourse has never been more heated. The complex issues that animate the health care debate have forced the American public to grapple with the exigencies of the present system with regard to economic, fiscal, and monetary policy, especially as they relate to philosophical, often ideologically driven approaches to the problem. Americans have also had to examine their ideas about the relationship of the individual to and interaction with the state and the varied social and cultural beliefs about what an American solution to the problem of health care looks like. In light of the need to keep students, researchers, and other interested readers informed and up-to-date on the issues surrounding health care in the U.S., this volume uses introductory essays followed by point/counterpoint articles to explore prominent and perennially important debates, providing readers with views on multiple sides of this complex issue. Features & Benefits: The volume is divided into three sections, each with its own Section Editor: Quality of Care Debates (Dr. Jennie Kronenfeld), Economic & Fiscal Debates (Dr. Mark Zezza), and Political, Philosophical, & Legal Debates (Prof. Wendy Parmet). Sections open with a Preface by the Section Editor to introduce the broad theme at hand and provide historical underpinnings. Each Section holds 12 chapters addressing varied aspects of the broad theme of the section. Chapters open with an objective, lead-in piece (or "headnote") followed by a point article and a counterpoint article. All pieces (headnote, point article, counterpoint article) are signed. For each chapter, students are referred to further readings, data sources, and other resources as a jumping-off spot for further research and more in-depth exploration. Finally, the volume concludes with a comprehensive index, and the electronic version of the book includes search-and-browse features, as well as the ability to link to further readings cited within chapters should they be available to the library in electronic format.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Prologue.- Chapter 1. Depressing Thoughts.- Chapter 2. Suicide and History.- Chapter 3. Suicide and Criminality.- Chapter 4. Suicide and Science.- Chapter 5. Distinguishing Differences.- Chapter 6. The Matter of Reporting.- Chapter 7. Mainstream Suicide.- Chapter 8. Aboriginal Suicide.- Chapter 9. The Matter of Rejection.- Chapter 10. The Matter of Prevention.- Chapter 11. A Matter of Economics.- Chapter 12. A Matter of Education.- Chapter 13. Kinds Hearts and Coroners.- Chapter 14. Reading Guide.- References.

In this book, Elie Metchnikoff presents three lectures on the prevention of infectious diseases. Metchnikoff was a Russian biologist who won the Nobel Prize in Physiology or Medicine in 1908 for his work on immunity. He believed that good hygiene and nutrition could prevent disease and extend life. The lectures cover topics such as the role of microbes in disease, the importance of cleanliness, and the benefits of vaccination. An informative and timely book for anyone interested in public health. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.