Addresses the fundamental question of what it means to be alive from the perspective of a microbe, E. coli, that exists within all human beings, examining the germ's evolution and its important role in the history of biology.

Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured.Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation.This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.

Astrophysicist and author Mario Livio investigates perhaps the most human of all our characteristics—curiosity—in this “lively, expert, and definitely not dumbed-down account” ( Kirkus Reviews ) as he explores our innate desire to know why . Experiments demonstrate that people are more distracted when they overhear a phone conversation—where they can know only one side of the dialogue—than when they overhear two people talking and know both sides. Why does half a conversation make us more curious than a whole conversation? “Have you ever wondered why we wonder why? Mario Livio has, and he takes you on a fascinating quest to understand the origin and mechanisms of our curiosity. I thoroughly recommend it.” (Adam Riess, Nobel Prize Winner in Physics, 2011). Curiosity is not only at the heart of mystery and suspense novels, it is also essential to other creative endeavors, from painting to sculpture to music. It is the principal driver of basic scientific research. Even so, there is still no definitive scientific consensus about why we humans are so curious, or about the mechanisms in our brain that are responsible for curiosity. In the ever-fascinating Why? Livio interviewed scientists in several fields to explore the nature of curiosity. He examined the lives of two of history’s most curious geniuses, Leonardo da Vinci and Richard Feynman. He also talked to people with boundless curiosity: a superstar rock guitarist who is also an astrophysicist; an astronaut with degrees in computer science, biology, literature, and medicine. What drives these people to be curious about so many subjects? An astrophysicist who has written about mathematics, biology, and now psychology and neuroscience, Livio has firsthand knowledge of his subject which he explores in a lucid, entertaining way that will captivate anyone who is curious about curiosity.

This book explores changing American views of race mixing in the twentieth century, showing how new scientific ideas transformed accepted notions of race and how those ideas played out on college campuses in the 1960s. In the 1930s, it was not unusual for medical experts to caution against miscegenation, or race mixing, espousing the common opinion that it would produce biologically dysfunctional offspring. By the 1960s the scientific community roundly refuted this theory. The author traces this revolutionary shift in scientific thought, explaining how developments in modern population biology, genetics, and anthropology proved that opposition to race mixing was a social prejudice with no justification in scientific knowledge. In the 1960s, this new knowledge helped to change attitudes towards race and discrimination, especially among college students. Their embrace of social integration caused tension on campuses across the country. Students rebelled against administrative interference in their private lives, and university regulations against interracial dating became a flashpoint in the campus revolts that revolutionized American educational institutions. The author's provocative study is a personal one, featuring interviews with mixed-race couples and stories from the author's student years at the University of Pittsburgh. As such, this book offers a unique perspective on how contentious debates taking place on college campuses reflected shifts in race relations in the larger society. -- from Back Cover

This collection of essays explains and encourages new reflection on Paul Rabinows pioneering project to anthropologize the West. His goal is to exoticize the Western constitution of reality, emphasize those domains most taken for granted as universal, and show how their claims to truth are linked to particular social practices, hence becoming effective social forces. He has recently begun to focus on the core of Western rationality, in particular the practices of molecular biology as they apply to our understanding of human nature. This book moves in new directions by posing questions about how scientific practice can be understood in terms of ethics as well as in terms of power.The topics include how French socialist urban planning in the 1930s engineered the transition from city planning to life planning; how the discursive and nondiscursive practices of the Human Genome Project and biotechnology have refigured life, labor, and language; and how a debate over patenting cell lines and over the dignity of life required secular courts to invoke medieval notions of the sacred. Building on an ethnographic study of the invention of the polymerase chain reaction--which enables the rapid production of specific sequences of DNA in millions of copies Rabinow, in the final essay, reflects in dialogue with biochemist Tom White on the place of science in modernity, on science as a vocation, and on the differences between the human and natural sciences.

Explores the complex factors and long line of "ancestors" that have contributed to human sexuality and human sexual behavior

"Is life different from the non-living? If so, how? And how, in that case, does biology, as the study of living things, differ from other sciences? These questions lie at the heart of The Philosophy of Biology, and are traced through an exploration of episodes in the history of biology and philosophy. The book begins with Aristotle, then moves on to Descartes, comparing his position with that of Harvey. From the eighteenth century, the authors consider Buffon and Kant. From the nineteenth century, the authors examine the Cuvier-Geoffroy debate, pre-Darwinian geology and natural theology, Darwin, and the transition from Darwin to the revival of Mendelism. Two chapters on the twentieth century deal with the Modern Evolutionary Synthesis and such questions as the species problem, the reducibility or otherwise of biology to physics and chemistry, and the problem of biological explanation in terms of function and teleology. The final chapters reflect on the question of human nature and the implications of the philosophy of biology for the philosophy of science in general."--Jacket