Connected solely by a desk of enormous dimension and many drawers that exerts a power over those who possess it or give it away, three people--a lonely American novelist clinging to the memory of a poet who has mysteriously vanished in Chile, an old man in Israel facing the imminent death of his wife of 51 years, and an esteemed antiques dealer tracking down the things stolen from his father by the Nazis--struggle to create a meaningful permanence in the face of inevitable loss

WINNER OF THE 2005 HOLOCAUST LITERATURE AWARD. SHORTLISTED FOR THE COMMONWEALTH WRITERS' PRIZE

At forty, the writer Nathan Zuckerman comes down with a mysterious affliction--pure pain, beginning in his neck and shoulders, invading his torso, and taking possession of his spirit. Zuckerman, whose work was his life, is unable to write a line. Now his work is trekking from one doctor to another, but none can find a cause for the pain and nobody can assuage it. Zuckerman himself wonders if the pain can have been caused by his own books. And while he is wondering, his dependence on painkillers grows into an addiction to vodka, marijuana, and Percodan. The Anatomy Lesson is a great comedy of illness written in what the English critic Hermione Lee has described as "a manner at once...brash and thoughtful... lyrical and wry, which projects through comic expostulations and confessions...a knowing, humane authority." The third volume of the trilogy and epilogue Zuckerman Bound, The Anatomy Lesson provides some of the funniest scenes in all of Roth's fiction as well as some of the fiercest. From the Trade Paperback edition.

A shocking phone call in the first sentence sparks a soaring tour-de-force saga in this tale of two brothers, years apart in age, who have become close late in life. But the freakish death of one at the book's outset sends the other reeling into a shattered yet strangely exhilarating re-visitation of their lives together.