Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer, yet her cells--taken without her knowledge--became one of the most important tools in medicine. The first "immortal" human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer and viruses; helped lead to in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks is buried in an unmarked grave. Her family did not learn of her "immortality" until more than twenty years after her death, when scientists began using her husband and children in research without informed consent. The story of the Lacks family is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of--From publisher description.

NEW YORK TIMES BESTSELLER - A powerful collection of the influential columnist's most important works--featuring rare speeches and a major new essay about today's populist movements and the future of global democracy "Charles will be remembered as one of the greatest public intellects of his generation."--John McCain In his decades of work as America's preeminent political commentator, whether writing about statecraft and foreign policy or reflecting on more esoteric topics such as baseball, spaceflight and medical ethics, Charles Krauthammer elevated the opinion column to a form of art. This collection features the columns, speeches and unpublished writings that showcase the best of his original thought and his last, enduring words on the state of American politics, the nature of liberal democracy and the course of world history. The book also includes a deeply personal section offering insight into Krauthammer's beliefs about what mattered most to him: friendship, family and the principles he lived by. The Point of It All is a timely demonstration of what made Charles Krauthammer the most celebrated American columnist and political thinker of his generation, a revealing look at the man behind the words and a lasting testament to his belief that anyone with an open and honest mind can grapple deeply with the most urgent questions in politics and in life.

A history of the T4 program, or "euthanasia program", in Nazi Germany - that is, the murder of handicapped persons by the Nazis. This program was preceded by the politicization of science, which incorporated popular prejudices into "scientific" theories and declared some individuals and even "racial" groups, like Jews and Gypsies, to be "valueless"; by the eugenic movement; and by the misuse of scientific hypotheses by politicians. The policy of exclusion of the "racially inferior" stood at the center of the Nazi utopia. The "euthanasia program", implemented in 1939-40, paved the way for the mass extermination of Jews and Gypsies in 1942-44. Many of those involved in the T4 program (e.g. Franz Stangl) were later involved in the operation of the death camps. Special attention is devoted to the murder of handicapped Jews. These, progressively excluded from the public welfare system and from the medical institutions, were concentrated in 1939-40 in special Jewish hospitals and later killed in the course of the "euthanasia program".

NOW FEATURING A NEW AFTERWORD, "PANDEMIC ETHICS" From two eminent scholars comes a provocative examination of bioethics and our culture’s obsession with having it all without paying the price. Shockingly, the United States has among the lowest life expectancies and highest infant mortality rates of any high-income nation, yet, as Amy Gutmann and Jonathan D. Moreno show, we spend twice as much per capita on medical care without insuring everyone. A “remarkable, highly readable journey” (Judy Woodruff ) sure to become a classic on bioethics, Everybody Wants to Go to Heaven but Nobody Wants to Die explores the troubling contradictions between expanding medical research and neglecting human rights, from testing anthrax vaccines on children to using brain science for marketing campaigns. Providing “a clear and compassionate presentation” ( Library Journal ) of such complex topics as radical changes in doctor-patient relations, legal controversies over in vitro babies, experiments on humans, unaffordable new drugs, and limited access to hospice care, this urgent and incisive history is “required reading for anyone with a heartbeat” (Andrea Mitchell).

Although organ transplantation is the preeminent medical miracle of the last quarter of a century, Many Sleepless Nights is the first book to go beyond the headlines and describe the patients who have embraced this last chance to hold on to life, the intricate medical procedures that can save them, the surgeons and nurses who work in this emotionally charged world, and the ethics which complicate this miracle high-tech therapy. Lee Gutkind was granted unconditional access to the world's largest transplant center - the University of Pittsburgh's Presbyterian-University and Children's hospitals, where there is an organ transplant every eight hours, 365 days per year. For four years he immersed himself in the frantic night-and-day world of transplantation, living side by side with transplant candidates and recipients, jetting though the night with organ procurement teams, monitoring patients with surgeons and nurses, observing in the operating room, participating in the ethical and psychosocial evaluations of prospective patients which help to determine who will receive scarce organs. During his four years at Presbyterian and Children's Hospitals, Gutkind established close relationships with many patients, and his portrayal of them, living and sometimes dying under unbelievable stress, is a moving and dramatic statement about the capacity of human beings to endure. Many Sleepless Nights also outlines the history of organ transplantation and tells the story of the large and complex medical teams behind the operation. It captures the tension of the search for viable organs; the pressure decisions about which patients, among many, will receive them; and the surgery itself.Its vivid portrayal of the transplant pioneer Thomas Starzl - a man obsessed with saving lives - shows how a major innovator in American medicine functions during days and nights of extreme pressure.

Medical Progress and Social Reality is an anthology of nineteenth-century literature on medicine and medical practice. Situated at the interdisciplinary juncture of medicine, history, and literature, it includes mostly fictional but also some nonfictional works by British, French, American, and Russian writers that describe the day-to-day social realities of medicine during a period of momentous change. Issues addressed in these works include the hierarchy in the profession, the use of new instruments such as the stethoscope, the advent of women doctors, the function of the hospital, and the shifting balance of power between physicians and patients. The volume provides an introductory overview of the most important aspects of medical progress in the nineteenth century, and it includes an annotated bibliography of further readings in medical history and literature. Selections from Anthony Trollope, George Eliot, Gustave Flaubert, Sarah Orne Jewett, Sinclair Lewis, Mikhail Bulgakov, and others are included, as well as the American Medical Association's 1847 Code of Ethics.

"I have been a Jew during Fascism, a bourgeois under Communism, a rebel defeated in an uprising, a refugee among the free, and a have-not amid plenty. This book contains over 60 stories that range from my youth in Hungary, the ordeal of a death march and concentration camps, the oppression of the Communist dictatorship, the promise and defeat of the Hungarian Revolution and, finally, my American years"--Preminary pages

In Everything Is Possible, Dan Abraham, the legendary founder of Slim-Fast, recounts the story of his personal and business life, starting from his childhood and army years and his purchase of Thompson Medical for $5,000 when he was in his early twenties, and culminating in the sale of Slim-Fast for $2.3 billion in 2000. At the heart of Everything Is Possible are 16 life lessons that Abraham has picked up in sixty years of a hard-working business career. Among them: There is no such thing as a mistake (see pages 198–202) Why I always insured that my suppliers made a profit (see pages 208–9) The philosophy of continuous improvement (see pages 202–5) If you have a theory and the facts dispute it, drop your theory (pages 205–8) The realization that we all have both good and bad luck in our lives, but many of us don't prepare for either (pages 216–9) I never saw a man pick a fight with a stronger man (pages 191–5) But this memoir, a brilliant guide for anyone starting and growing a business, is about far more than business. Abraham tells the heartwarming story of growing up in a modest home in Long Beach, New York, and the lessons he learned from his mother, father, and one high school teacher that have guided him ever since. And there is more, much more: a discussion of his beliefs about the pleasure of giving; what he has learned from Judaism about ethics and the Golden Rule; and what he learned from his experiences with the FDA about the importance of compromise and about the necessity to fight hard when you believe you're right. At a time, when newspapers are filled with reports of business fraud and deceptions, and when so many people believe that to have spectacular success in business you have to be ruthless and dishonest, this is an account of a business life that has been lived honorably, passionately, and successfully, and with fun. Everything Is Possible is a book to be savored and shared with young and old alike.

"The book is readable and challenging; readers will never see psychiatry in the same way again." -- Choice Reviews Originally called mad-doctoring, psychiatry began in the seventeenth century with the establishing of madhouses and the legal empowering of doctors to incarcerate persons denominated as insane. Until the end of the nineteenth century, every relationship between psychiatrist and patient was based on domination and coercion, as between master and slave. Psychiatry, its emblem the state mental hospital, was a part of the public sphere, the sphere of coercion. The advent of private psychotherapy, at the end of the nineteenth century, split psychiatry in two: some patients continued to be the involuntary inmates of state hospitals; others became the voluntary patients of privately practicing psychotherapists. Psychotherapy was officially defined as a type of medical treatment, but actually was a secular-medical version of the cure of souls. Relationships between therapist and patient, Thomas Szasz argues, was based on cooperation and contract, as is relationships between employer and employee, or, between clergyman and parishioner. Psychotherapy, its emblem the therapist's office, was a part of the private sphere, the contract. Through most of the twentieth century, psychiatry was a house divided-half-slave, and half-free. During the past few decades, psychiatry became united again: all relations between psychiatrists and patients, regardless of the nature of the interaction between them, are now based on actual or potential coercion. This situation is the result of two major "reforms" that deprive therapist and patient alike of the freedom to contract with one another: Therapists now have a double duty: they must protect all mental patients-involuntary and voluntary, hospitalized or outpatient, incompetent or competent-from themselves. They must also protect the public from all patients. Persons designated as mental patients may be exempted from responsibility for the deleterious consequences of their own behavior if it is attributed to mental illness. The radical differences between the coercive character of mental hospital practices in the public sphere, and the consensual character of psychotherapeutic practices in the private sphere, are thus destroyed. At the same time, as the scope of psychiatric coercion expands from the mental hospital to the psychiatrist's office, its reach extends into every part of society, from early childhood to old age. Thomas Szasz is professor of psychiatry emeritus at the State University of New York Health Science Center in Syracuse, New York and Adjunct Scholar at the Cato Institute, Washington, DC. He is the author of over two dozen books in fifteen languages, including The Myth of Mental Illness and most recently, Pharmacracy: Medicine and Politics in America . "The book is readable and challenging; readers will never see psychiatry in the same way again."-- Choice "Szasz now appears to have been transformed into an ally rather than an enemy of the National Health Service general adult psychiatrist. Szasz's project has always been to argue passionately for a boundry of demarcation around the responsibility and power of psychiatry....But what saves this book from being just another mugging of psychiatry is that Szasz does raise a fundamental question at the core of our discipline. If we restricted our attention only to those clients who wanted to see a psychiatrist, and disengaged from all those who really didn't, how different might our professional practice and experience be?"-- The British Journal of Psychiatry

Neonatal intensive care has been one of the most morally controversial areas of medicine during the past thirty years. This study examines the interconnected development of four key aspects of neonatal intensive care: medical advances, ethical analysis, legal scrutiny, and econometric evaluation. The authors assert that a dramatic shift in societal attitudes toward newborns and their medical care was a stimulus for and then a result of developments in the medical care of newborns. They divide their analysis into three eras of neonatal intensive care. The first, characterized by the rapid advance of medical technology from the late 1960s to the Baby Doe case of 1982, established neonatal care as a legitimate specialty of medical care, separate from the rest of pediatrics and medicine. During this era, legal scholars and moral philosophers debated the relative importance of parental autonomy, clinical prognosis, and children's rights. The second era, beginning with the Baby Doe case (a legal battle that spurred legislation mandating that infants with debilitating birth defects be treated unless the attending physician deems efforts to prolong life "futile"), stimulated efforts to establish a consistent federal standard on neonatal care decisions and raised important moral questions concerning the meaning of "futility" and of "inhumane" treatment. In the third era, a consistent set of decision-making criteria and policies was established. These policies were the result of the synergy and harmonization of newly agreed upon ethical principles and newly discovered epidemiological characteristics of neonatal care. Tracing the field's recent history, notable advances, and considerable challenges yet to be faced, the authors present neonatal bioethics as a paradigm of complex conversation among physicians, philosophers, policy makers, judges, and legislators which has led to responsible societal oversight of a controversial medical innovation.

My 'discovery' of the Polish School of philosophy of medicine stemmed from my studies in the genesis of Ludwik Fleck's epistemology. These studies, and my interest in the scientific roots of Fleck's epistemology were a nearly 'natural' result of my own biography: like Fleck I had been trained, an had worked as an immunologist, and had later switched to studies in the social history of medicine and biology. Moreover, it so happened that Fleck's book, Genesis and Development of a Scientific Fact -the description of a science as it is, not as it should be -was the first epistemological study in which I found echos of my experience in the laboratory. My interest in Fleck was also highlightened by the fact that in his works, and, as I discovered later, in the works of his predecessors of the Polish School of philosophy of medicine, was formulated the problem that had stimulated my interest in the history of medicine and biology, and is still central to my present investigations: the relationships between biological knowledge and clinical practice. The writing of the book was made possible through to the help of many colleagues and friends. The unfailing support for my research, whatever its subject might be, from my colleagues from Unit 158 of INSERM and in particular from its head Patrice Pinell, has made my study of the Polish School possible.