"A brilliant and brave investigation by Michael Pollan, author of five New York Times best sellers, into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into the experience of various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both struggle and beauty, we can do our best to be fully present and find meaning in our lives"--

"What if you woke up one morning and found you'd acquired another self--a double who was almost you and yet not you at all? What if that double shared many of your preoccupations but, in a twisted, upside-down way, furthered the very causes you'd devoted your life to fighting against? Not long ago, the celebrated activist and public intellectual Naomi Klein had just such an experience--she was confronted with a doppelganger whose views she found abhorrent but whose name and public persona were sufficiently similar to her own that many people got confused about who was who. Destabilized, she lost her bearings, until she began to understand the experience as one manifestation of a strangeness many of us have come to know but struggle to define: AI-generated text is blurring the line between genuine and spurious communication; New Age wellness entrepreneurs turned anti-vaxxers are scrambling familiar political allegiances of left and right; and liberal democracies are teetering on the edge of absurdist authoritarianism, even as the oceans rise. Under such conditions, reality itself seems to have become unmoored. Is there a cure for our moment of collective vertigo? Naomi Klein is one of our most trenchant and influential social critics, an essential analyst of what branding, austerity, and climate profiteering have done to our societies and souls. Here she turns her gaze inward to our psychic landscapes, and outward to the possibilities for building hope amid intersecting economic, medical, and political crises. With the assistance of Sigmund Freud, Jordan Peele, Alfred Hitchcock, and bell hooks, among other accomplices, Klein uses wry humor and a keen sense of the ridiculous to face the strange doubles that haunt us--and that have come to feel as intimate and proximate as a warped reflection in the mirror. Combining comic memoir with chilling reportage and cobweb-clearing analysis, Klein seeks to smash that mirror and chart a path beyond despair. Doppelganger asks: What do we neglect as we polish and perfect our digital reflections? Is it possible to dispose of our doubles and overcome the pathologies of a culture of multiplication? Can we create a politics of collective care and undertake a true reckoning with historical crimes? The result is a revelatory treatment of the way many of us think and feel now--and an intellectual adventure story for our times"--

"For as long as he has served at the highest levels of business and government, Vice President Dick Cheney has also been one of the world's most prominent heart patients. Now, for the first time ever, Cheney, together with his longtime cardiologist Jonathan Reiner, MD, shares the very personal story of his courageous thirty-five-year battle with heart disease, from his first heart attack in 1978 to the heart transplant he received in 2012. In 1978, when Cheney suffered his first heart attack, he received essentially the same treatment as President Eisenhower had in 1955. Since then, cardiac medicine has evolved in extraordinary ways, and Cheney has benefited from nearly every medical and technological breakthrough along the way. At each juncture, when Cheney faced a new health challenge, the technology was one step ahead of his disease. In many ways, Cheney's story is the story of the evolution of modern cardiac care. Heart is the riveting, singular memoir of both doctor and patient, tracking their relationship as it unfolds over many years and crises. Like no US politician has before him, Cheney opens up about his health struggles, sharing harrowing, never-before-told stories about the challenges he faced during a perilous time in our nation's history. Dr. Reiner provides his perspective on Cheney's case and also gives readers a fascinating glimpse into his own education as a doctor. He masterfully chronicles the important discoveries, radical innovations, and cutting-edge science that have changed the face of medicine and saved countless lives. Powerfully braiding science with story and the personal with the political, Heart is a sweeping, inspiring, and ultimately optimistic book that will give hope to the millions of Americans affected by heart disease"--

A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” ( American Scientist ), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.

Nobelist Eric Kandel's account of how his personal quest to understand memory intersected with the emergence of a new science. In Search of Memory relates the astonishing story of how four different and distinct disciplinesbehaviorist psychology, cognitive psychology, neuroscience, and molecular biologyconverged into a powerful new science of mind. Through its profound insights into thought, perception, action, recollection, and mental illness, this new science is revolutionizing our understanding of learning and memory while simultaneously showing great promise for more effective healing. The narrative follows Eric R. Kandel through the last five decades, focusing on Vienna, where he became fascinated with memory. With intrepid scientific ardor, Kandel was captivated first by history and psychoanalysis, then by neurobiology, and finally by the biological processes of memory. His resulting, multifaceted perspective was the foundation for his path-breaking research that will continue to dominate modern thoughtnot only in science but in culture at large. 50 illustrations.

This book speculates about the important inventions, scientific discoveries, and political and social developments, which may occur during the coming millennium. It does this by presenting -- through the eyes of a fictitious author living in the year 3000 -- a list of the 100 men and women who have had the greatest impact on world history and on the everyday lives of individuals. The hundred persons are ranked in order of their influence. The main section of the book consists of short biographies of those 100 persons, describing what each person accomplished, and why that person is so important. Forty-five of the entries are actual historical personages. These include such well known figures as Jesus Christ, Confucius, Charles Darwin, Christopher Columbus, Albert Einstein, and George Washington. Among the fifty-five entries from the third millennium are: Sue Ellen Green (who develops a cancer vaccine); Miguel Carranza (chief founder of the United World Federation); Stella Ricardo Garcia (architect and formscaper); Mika Kivikoski (who develops the technology to control the weather); and Shu Gungwu (who finds the solution to the baffling "mind-body problem"). Other topics treated include: space travel and space colonies; medical advances (such as artificial organs, and reversible sex-change operations); arts and entertainment (including music, literature, the visual arts, and sports and games); solar power; philosophy (including political theory, epistemology, semantics, and ethics); mathematics, pollution control, robots, brainwashing; nuclear warfare; robots; and artificial intelligence. The book includes a historical chart (listing the main events of both the actual past and the projected future), a list of honorable mentions (and their accomplishments); a glossary, and an extensive index.

Irena Koprowska's autobiography illuminates the struggles of a young immigrant woman to combine family responsibilities and a demanding medical career. Irena Koprowska's autobiography chronicles the life and struggles of an immigrant woman who successfully pursued a career while raising a family. In the process, she became an award-winning physician, professor, and research pioneer at a time in history when it was believed a woman's place was in the home. Born in Warsaw in 1917, Irena Koprowska was married, pregnant, and a physician by the age of twenty-two. Forced to flee the Nazis, first in Poland and then in France, she fled to Brazil in 1940. Four years later she immigrated to the United States. Unable to speak English, she started her academic career as a volunteer at the Department of Pathology at Cornell University Medical College. During the years of her subsequent Research Fellowships at Cornell University Medical College, she worked with George N. Papanicolaou, inventor of the Pap smear. The two co-authored a case report of the earliest diagnosis of lung cancer by a sputum smear. Eight years later, she was appointed Assistant Professor of Pathology at State University of New York Downstate Medical College and went on to become the first woman physician to become a full professor at Hahnemann Medical College and Hospital (now known as Hahnemann University) in Philadelphia. Later she joined the faculty of Temple University Medical School where, upon her retirement in 1987, she became Professor Emerita. She was recognized as "Woman Physician of the Year" by a Gold Medicus award of the Polish American Society in 1977 and received the Papanicolaou Award of the AmericanSociety of Cytology in 1985.

This series of dialogues between the spiritual and the scientific is framed by Klein's deep knowledge of cell biology.