With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Here are some facts: Women live longer than men. They have stronger immune systems. They're better at fighting cancer and surviving famine, and even see the world in a wider variety of colours. They are simply stronger than men at every stage of life. Why is this? And why are we taught the opposite? To find out, Dr. Sharon Moalem drew on his own medical experiences - treating premature babies in the neonatal intensive care unit; recruiting the elderly for neurogenetic studies; tending to HIV-positive orphans in Thailand - and tried to understand why in every instance men were consistently less likely to thrive. The answer, he discovered, lies in our genetics: two X chromosomes offer a powerful survival advantage. With clear, captivating prose that weaves together eye-opening research, case studies, diverse examples ranging from the behaviour of honeybees to American pioneers, as well as experiences from his personal life and his own patients, Moalem explains why genetic females triumph over males when it comes to resiliency, intellect, stamina, immunity and much more. He also calls for a reconsideration of our male-centric, one-size-fits-all view of medical studies and even how we prescribe medications - a view that still sees women through the lens of men. Revolutionary and yet utterly convincing, The Better Half will make you see humanity and the survival of our species anew.[Bokinfo]

"Titillating and provocative essays from one of the freshest voices in science today -- Why do testicles hang the way they do? Is there an adaptive function to the female orgasm? What does it feel like to want to kill yourself? Does "free will" really exist? And why is the penis shaped like that anyway? In Why Is the Penis Shaped Like That?, the research psychologist and award-winning columnist Jesse Bering features more than thirty of his most popular essays from Scientific American and Slate, as well as two new pieces, that take readers on a bold and captivating journey through some of the most taboo issues related to evolution and human behavior. Exploring the history of cannibalism, the neurology of people who are sexually attracted to animals, the evolution of human body fluids, the science of homosexuality, and serious questions about life and death, Bering astutely covers a generous expanse of our kaleidoscope of quirks and origins. With his characteristic irreverence and trademark cheekiness, Bering leaves no topic unturned or curiosity unexamined, and he does it all with an audaciously original voice. Whether you are interested in the psychological history behind the many facets of sexual desire or the evolutionary patterns that have dictated our current mystique and phallic physique, Why Is the Penis Shaped Like That? is bound to create lively discussion and debate for years to come"--

Finalist for the Los Angeles Times Book Prize From the man who Oliver Sacks hailed as “one of the best scientist/writers of our time,” a collection of sharply observed, uproariously funny essays on the biology of human culture and behavior. In the tradition of Stephen Jay Gould and Oliver Sacks, Robert Sapolsky offers a sparkling and erudite collection of essays about science, the world, and our relation to both. “The Trouble with Testosterone” explores the influence of that notorious hormone on male aggression. “Curious George’s Pharmacy” reexamines recent exciting claims that wild primates know how to medicate themselves with forest plants. “Junk Food Monkeys” relates the adventures of a troop of baboons who stumble upon a tourist garbage dump. And “Circling the Blanket for God” examines the neurobiological roots underlying religious belief. Drawing on his career as an evolutionary biologist and neurobiologist, Robert Sapolsky writes about the natural world vividly and insightfully. With candor, humor, and rich observations, these essays marry cutting-edge science with humanity, illuminating the interconnectedness of the world’s inhabitants with skill and flair.

"Totem and Taboo" is a collection of four essays by Sigmund Freud that were published together in German in 1913. Freud sought to apply his theories of psychoanalysis to the study of anthropology and early human history. The four essays cover a wide range of topics. In "The Horror of Incest", Freud examines the varied and common rules in primitive cultures that limit contact between members of the same family. In "Taboo and Emotional Ambivalence," Freud posits that primitive cultures and their attitudes about magical objects are similar to the behavior of people with neurotic psychological conditions in the modern world. In "Animism, Magic and the Omnipotence of Thought," Freud draws comparisons between the primitive belief in magic and magical animals to obsessive and compulsive disorders. Finally, in "The Return of Totemism in Childhood," Freud, influenced by one of Charles Darwin's theories about the male-dominated arrangement of early human societies, looks for parallels with his own Oedipus complex theory in the structure of primitive cultures. A classic and influential work of early psychoanalysis, "Totem and Taboo" is an important read for students of both psychology and social anthropology.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Methods in Neuronal Modeling is the first technical handbook on computational neuroscience. Written for researchers and theoreticians alike, it outlines methods and techniques used for simulating on digital computers the functional properties of single neurons from synapses, dendrites, single cells; and small invertebrate networks to large scale neural networks in the mammalian nervous system. The use of new experimental tools such as selective staining methods, membrane patch electrodes, voltage and calcium-dependent dyes, and multielectrode recordings, together with the, advent of universally available powerful computing, makes it possible to construct detailed and realistic models of neuronal systems. Methods in Neuronal Modeling addresses such questions as what can and should be simulated and what techniques should be used; what experimental parameters are crucial for such simulations, and whether these models may be verified experimentally. Chapters cover simulation of passive dendritic trees, compartmental models of single cells including neurons with a number of different ionic channels, calcium current dynamics, simulations of small invertebrate networks, simulations of the mammalian cortex, connectionists' models, and the use of parallel computers in modeling neural networks. Although the chapters were written by several authors, they are uniform in structure and notation. Detailed examples are given to clarify the different approaches. Each chapter concludes with a description of the model discussed and the details of its implementation on the computer. Christof Koch is an Assistant Professor of Computation and Neural Systems at the California Institute of Technology. Idan Segev is a Lecturer in Neurobiology at the Institute of Life Science, Hebrew University of Jerusalem. Methods in Neuronal Modeling inaugurates the new series in Computational Neuroscience, edited by Terrence J. Sejnowski and Tomaso Poggio. A Bradford Book.

This enticing collection is as devoted to the profound power of figures of speech as any oration of old Hellas. Metaphor reigns as we encounter the identification of our Earth as a Single, integrative organism, a tale told in image and passion. The discoveries and conjectures upon which this grand view rest are here as well. I have enjoyed these two dozen pieces hugely. No family tree of animal life but must somewhere disclose a cousinly infolding. We are compact of life past, and the looped handing down is more complex than the Mendel-Morgan dance of chromosomes and genes. That dance is essential, certainly, but it is the vital editing of an epic and many-rooted work, a book more like the Bible than like one great artists Remembrance of Things Past. We follow a few old shelves of bound DNA, not just a single book. Our major biochemical package for oxidative metabolism was de scribed in a small DNA manual, somehow engulfed to become an or ganelle within a lucky ancient ancestral anaerobe, and passed ever since viii FOREWORD from mother to offspring outside of the chromosome shuffie. The sperm do carry half the compact genetic message of the human DNA, but they are too small to transfer this equally essential symbiotic one that comes down from the mothers, within roomy egg after roomy egg.

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics.

One of The New York Times Critics' Picks of the Year From acclaimed psychoanalyst Adam Phillips, a meditation on what we must give up to feel more alive. To give up or not to give up? The question can feel inescapable but the answer is never simple. Giving up our supposed vices is one thing; giving up on life itself is quite another. One form of self-sacrifice feels positive, something to admire and aspire to, while the other is profoundly unsettling, if not actively undesirable. There are always, it turns out, both good and bad sacrifices, but it is not always clear beforehand which is which. We give something up because we believe we can no longer go on as we are. In this sense, giving up is a critical moment—an attempt to make a different future. In On Giving Up , the acclaimed psychoanalyst Adam Phillips illuminates both the gaps and the connections between the many ways of giving up and helps us to address the central question: What must we give up in order to feel more alive?

Spaceflight historian Amy Shira Teitel tells the riveting story of the female pilots who each dreamed of being the first American woman in space. When the space age dawned in the late 1950s, Jackie Cochran held more propeller and jet flying records than any pilot of the twentieth century-man or woman. She had led the Women's Auxiliary Service Pilots during the Second World War, was the first woman to break the sound barrier, ran her own luxury cosmetics company, and counted multiple presidents among her personal friends. She was more qualified than any woman in the world to make the leap from atmosphere to orbit. Yet it was Jerrie Cobb, twenty-five years Jackie's junior and a record-holding pilot in her own right, who finagled her way into taking the same medical tests as the Mercury astronauts. The prospect of flying in space quickly became her obsession. While the American and international media spun the shocking story of a "woman astronaut" program, Jackie and Jerrie struggled to gain control of the narrative, each hoping to turn the rumored program into their own ideal reality-an issue that ultimately went all the way to Congress. This dual biography of audacious trailblazers Jackie Cochran and Jerrie Cobb presents these fascinating and fearless women in all their glory and grit, using their stories as guides through the shifting social, political, and technical landscape of the time.

"This book was written for the 2018 NSF-CBMS conference on 'Mathematical biology: modeling and analysis' hosted by Howard University in Washington, DC, May 21-25, 2018." -- Preface, page viii.

In this remarkable book by one of the great psychologists and neurologists of the early twentieth century, Kurt Goldstein presents a summation of his “holistic” theory of the human organism. In the course of his studies on brain-damaged soldiers during the First World War, Goldstein became aware of the failure of contemporary biology and medicine to genuinely understand both the impact of such injuries and the astonishing adjustments that patients made to them. He challenged reductivist approaches that dealt with “localized” symptoms, insisting instead that an organism be analyzed in terms of the totality of its behavior and interaction with its surrounding milieu. He was especially concerned with the breakdown of organization and the failure of central cerebral controls that take place in catastrophic responses to situations such as physical or mental illness. But Goldstein was equally attuned to the amazing powers of the organism to readjust to such devastating losses, if only by withdrawal to a more limited range of activity that it could manage by a redistribution of its reduced energies, thus reclaiming as much wholeness as new circumstances allowed. Goldstein’s concepts in The Organism have had a major impact on philosophical and psychological thought throughout this century, as can be seen in the work of Maurice Merleau-Ponty, Georges Canguilhem, Ernst Cassirer, Ludwig Binswanger, and Roman Jakobson, not to mention the wide-ranging field of Gestalt psychology.

First published in 1999. This is Volume XVI of twenty-one of a series on Cognitive Psychology. Written in 1926, considered from a philosophic viewpoint, this is an English translation of Professor Rignano's work, Biological Memory," which gives an exhaustive analysis of the differences which distinguish living from non-living substance and his attempts to account for these differences as the manifold effects of a single quality.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.