This tale of two families is set on a grand scale, as James Thomas Flexner brings his talents to bear on his own noteworthy heritage. An American Saga is an historical narrative, grounded on documentary sources, which ends with the marriage of Helen Thomas and Simon Flexner. The account deals equally with the lives and the backgrounds of husband and wife, the author's parents. Simon Flexner was the famous medical investigator, discoverer of the "Flexner vacillus" and the "Flexner serum," who became the creating director of the Rockefeller Institute for Medical Research (now Rockefeller University) and eventually acknowledged leader of American medical science. The Kentucky-born son of impoverished German Jewish immigrants, he grew up in penury. As he never completed the eighth grade, he was almost completely self-educated when he appeared at the Johns Hopkins University before its celebrated medical school had been founded. Almost instantly he began making the discoveries that soon made him the leading younger medical scientist in the United States.

As the pastPresident ofthe Israel Society forAutism, it gives me great pleasure to c- gratulate Professor Schopler and his colleagues on the publication of their new book concerning the relationship between scientific research and treatment. When we in Israel began our specifically structured education program for young children with autism, our work was based on slim to scarceknow-how andinformation, and with no experience whatsoever. Whatever information we could gather was mostly from psychological educational centers in the U.S. One of the most important and significant connections was established between the TEACCH program of North Carolina, led and conducted by the two important scholars, Professor Eric Schopler and Professor Lee Marcus, and our Israel Society for Autism. During our many encounters, seminars, and conferences, we profited enormously from all their accumulated expertise and scientific research, while perhaps it was also an important experience for them to see how a young society with very limited means was eventually shaping its educational program and arriving at some excellent results. We, ofcourse, have the highest esteem for Governor Hunt who has been following this program with so much attention and support, and we still remember his visit to Israel with distinguished representatives of the TEACCH Program. I wish the new book every success. I know it will be an enormous contribution to all those who must cope with a difficult and painful issue—autism—for whom there is no end to the need for research and continuously improving methods of care and education.