Joining the ranks of modern myth busters, Dr. Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria. So why does disease exist? Moalem proposes that most common ailments--diabetes, hemochromatosis, cystic fibrosis, sickle cell anemia--came into existence for very good reasons. At some point they helped our ancestors survive some grand challenge to their existence. Examining the evolution of man, Moalem reveals the role genetic and cultural differences have played in the health and well-being of various races, including their susceptibility to disease. With mesmerizing insight, Moalem offers groundbreaking insight into: - How diabetes may be a biproduct of a mechanism that helped humans survive the Ice Age - Why African Americans living in the north might suffer from vitamin D deficiencies, - Why Asians can't drink as much alcohol as Europeans Revelatory, utterly engaging, and timely--Moalem ponders strongN1, the emerging Avian Flu virus--Why Redheads Feel More Pain and Asians Can't Drink will irrevocably change the way we think about our bodies and ourselves.

The untold story of how poison rocked Jazz Age New York City. A pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Chief medical examiner Charles Norris and toxicologist Alexander Gettler investigate a family mysteriously stricken bald, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler create revolutionary experiments to tease out even the wiliest compounds from human tissue. From the vantage of their laboratory it also becomes clear that murderers aren't the only toxic threat--modern life has created a kind of poison playground, and danger lurks around every corner.

"What happens when a society elevates victimhood to a virtue and decides that punishment is cruel? You get the disease Dr. Gad Saad calls suicidal empathy. And the West may be terminally infected" --

An eye-opening investigation into the history of diabetes research and treatment by the award-winning journalist and best-selling author of Why We Get Fat • "[Gary] Taubes’s meticulous, science-based work makes him the Bryan Stevenson of nutrition, an early voice in the wilderness for an unorthodox view that is increasingly becoming accepted."—Niel Barsky , The Guardian Before the discovery of insulin, diabetes was treated almost exclusively through diet, from subsistence on meat, to reliance on fats, to repeated fasting and near-starvation regimens. After two centuries of conflicting medical advice, most authorities today believe that those with diabetes can have the same dietary freedom enjoyed by the rest of us, leaving the job of controlling their disease to insulin therapy and other blood-sugar-lowering medications. Rather than embark on “futile” efforts to restrict sugar or carbohydrate intake, people with diabetes can lead a normal life, complete with the occasional ice-cream cake, side of fries, or soda. These guiding principles, however, have been accompanied by an explosive rise in diabetes over the last fifty years, particularly among underserved populations. And the health of those with diabetes is expected to continue to deteriorate inexorably over time, with ever-increasing financial, physical, and psychological burdens. In Rethinking Diabetes, Gary Taubes explores the history underpinning the treatment of diabetes, types 1 and 2, elucidating how decades-old research that is rife with misconceptions has continued to influence the guidance physicians offer—at the expense of their patients’ long-term well-being. The result of Taubes’s work is a reimagining of diabetes care that argues for a recentering of diet—particularly, fewer carbohydrates and more fat—over a reliance on insulin. Taubes argues critically and passionately that doctors and medical researchers should question the established wisdom that may have enabled the current epidemic of diabetes and obesity, and renew their focus on clinical trials to resolve controversies that are now a century in the making.

NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK • “A tour de force . . . a comprehensive and suitably furious guide to the political landscape of American healthcare . . . persuasive, shocking.” — The New York Times America’s Bitter Pill is Steven Brill’s acclaimed book on how the Affordable Care Act, or Obamacare, was written, how it is being implemented, and, most important, how it is changing—and failing to change—the rampant abuses in the healthcare industry. It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare. And it is the first complete, inside account of how President Obama persevered to push through the law, but then failed to deal with the staff incompetence and turf wars that crippled its implementation. But by chance America’s Bitter Pill ends up being much more—because as Brill was completing this book, he had to undergo urgent open-heart surgery. Thus, this also becomes the story of how one patient who thinks he knows everything about healthcare “policy” rethinks it from a hospital gurney—and combines that insight with his brilliant reporting. The result: a surprising new vision of how we can fix American healthcare so that it stops draining the bank accounts of our families and our businesses, and the federal treasury. Praise for America’s Bitter Pill “An energetic, picaresque, narrative explanation of much of what has happened in the last seven years of health policy . . . [Brill] has pulled off something extraordinary.” —The New York Times Book Review “A thunderous indictment of what Brill refers to as the ‘toxicity of our profiteer-dominated healthcare system.’ ” — Los Angeles Times “A sweeping and spirited new book [that] chronicles the surprisingly juicy tale of reform.” — The Daily Beast “One of the most important books of our time.” —Walter Isaacson “Superb . . . Brill has achieved the seemingly impossible—written an exciting book about the American health system.” — The New York Review of Books

"Mitch Albom has done it again with this moving memoir of love and loss. You can't help but fall for Chika. A page-turner that will no doubt become a classic." --Mary Karr, author of The Liars' Club and The Art of Memoir From the #1 New York Times bestselling author of Tuesdays With Morrie comes Mitch Albom's most personal story to date: an intimate and heartwarming memoir about what it means to be a family and the young Haitian orphan whose short life would forever change his heart. Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the forty-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. Chika's arrival makes a quick impression. Brave and self-assured, even as a three-year-old, she delights the other kids and teachers. But at age five, Chika is suddenly diagnosed with something a doctor there says, "No one in Haiti can help you with." Mitch and Janine bring Chika to Detroit, hopeful that American medical care can soon return her to her homeland. Instead, Chika becomes a permanent part of their household, and their lives, as they embark on a two-year, around-the-world journey to find a cure. As Chika's boundless optimism and humor teach Mitch the joys of caring for a child, he learns that a relationship built on love, no matter what blows it takes, can never be lost. Told in hindsight, and through illuminating conversations with Chika herself, this is Albom at his most poignant and vulnerable. Finding Chika is a celebration of a girl, her adoptive guardians, and the incredible bond they formed--a devastatingly beautiful portrait of what it means to be a family, regardless of how it is made.

Soul Made Flesh is the remarkable untold story of a dramatic turning point in history, the exciting discovery of how the human brain works. In an unprecedented examination of how the secrets of the brain were revealed in seventeenth-century England, award-winning author Carl Zimmer tells an extraordinary tale that unfurls against a deadly backdrop of civil war, plague, and the Great Fire of London. At the beginning of that turbulent century, no one knew how the brain worked or even what it looked like intact. By the century's close, the science of the brain had taken root, helping to overturn many of the most common misconceptions and dominant philosophies about man, God, and the universe. Presiding over the rise of this new scientific paradigm was the founder of modern neurology, Thomas Willis, a fascinating, sympathetic, even heroic figure who stands at the center of an extraordinary group of scientists and philosophers known as the Oxford circle. Chronicled here in vivid detail are their groundbreaking revelations and often gory experiments that first enshrined the brain as the chemical engine of reason, emotion, and madness, indeed as the very seat of the human soul. Called 'as fine a science essayist as we have' by The New York Times, Zimmer tells the story of this scientific revolution through the lives of a colorful array of alchemists, mystics, utopians, spies, revolutionaries, and kings. He recreates the religious, ethical, and scientific struggles involved in the pioneering autopsies of the brain carried out by Thomas Willis; the discovery of the circulation of blood by William Harvey and his flight from London with his besieged king, Charles I; René Descartes's persecution by Catholics and Protestants alike for his views of the brain and soul; and the experiments and personal dramas of gifted men who forever changed the way science is practiced as they simultaneously upended our view of our human selves and our place in the world. In this distant mirror to our own time of continuing scientific revolution and worldwide social upheaval, Zimmer brings to life the painstaking, innovative discoveries of Willis and his contemporaries, the taproots of the amazing work of today's neuroscientists, who continue to explore the brain, revealing the hidden workings of emotions, memories, and consciousness. Graced with beautiful illustrations by Christopher Wren, Soul Made Flesh conveys a contagious appreciation for the wonder of the brain, its structure, its many marvelous functions, and the implications for human identity, mind, and morality. It is the definitive history of the dawn of a world-changing science and attitude, the age of the brain and modern consciousness.

It was to Lucania, a desolate land in southern Italy, that Carlo Levi--a doctor, painter, philosopher, and man of letters--was confined as a political prisoner because of his opposition to Italy's Fascist government at the start of the Ethiopian war in 1935. While there, Levi reflected on the harsh landscape and its inhabitants, peasants who lived the same lives their ancestors had, constantly fearing black magic and the near presence of death. In so doing, Levi offered a starkly beautiful and moving account of a place and a people living outside the boundaries of progress and time.

NEW YORK TIMES BESTSELLER - A powerful collection of the influential columnist's most important works--featuring rare speeches and a major new essay about today's populist movements and the future of global democracy "Charles will be remembered as one of the greatest public intellects of his generation."--John McCain In his decades of work as America's preeminent political commentator, whether writing about statecraft and foreign policy or reflecting on more esoteric topics such as baseball, spaceflight and medical ethics, Charles Krauthammer elevated the opinion column to a form of art. This collection features the columns, speeches and unpublished writings that showcase the best of his original thought and his last, enduring words on the state of American politics, the nature of liberal democracy and the course of world history. The book also includes a deeply personal section offering insight into Krauthammer's beliefs about what mattered most to him: friendship, family and the principles he lived by. The Point of It All is a timely demonstration of what made Charles Krauthammer the most celebrated American columnist and political thinker of his generation, a revealing look at the man behind the words and a lasting testament to his belief that anyone with an open and honest mind can grapple deeply with the most urgent questions in politics and in life.

"A groundbreaking book about how technological advances in genomics and the extraction of ancient DNA have profoundly changed our understanding of human prehistory while resolving many long-standing controversies. Massive technological innovations now allow scientists to extract and analyze ancient DNA as never before, and it has become clear--in part from David Reich's own contributions to the field--that genomics is as important a means of understanding the human past as archeology, linguistics, and the written word. Now, in The New Science of the Human Past, Reich describes with unprecedented clarity just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population"--

2019 Reprint of 1961 Edition. Full facsimile of the original edition, not reproduced with Optical Recognition software. Reprint of the First Edition published in 1961. The Destruction of the European Jews is widely considered the landmark study of the Holocaust. First published in 1961, Raul Hilberg's comprehensive account of how Germany annihilated the Jewish community of Europe spurred discussion, galvanized further research, and shaped the entire field of Holocaust studies. Spanning the twelve-year period of anti-Jewish actions from 1933 to 1945, Hilberg's study encompasses Germany and all the territories under German rule or influence. Its principal focus is on the large number of perpetrators―civil servants, military personnel, Nazi party functionaries, SS men, and representatives of private enterprises―in the machinery of death. Contents: Dismissals -- Aryanizations -- Property taxes -- Blocked money -- Forced labor and wage regulations -- Income taxes -- Starvation measures -- The reich-protektorat area -- Ghetto formation -- Confiscations -- Labor exploitation -- Food controls -- preparations -- The first sweep -- The killing of the prisoners of war -- The intermediary stage -- The second sweep -- The reich-protektorat area -- Poland -- The semicircular arc -- Origins of the killing centers -- Organization, personnel, and maintenance -- Labor utilization -- Medical experiments -- Confiscations -- Killing operations -- Liquidation of the killing centers and the end of the destruction process.

A history of the T4 program, or "euthanasia program", in Nazi Germany - that is, the murder of handicapped persons by the Nazis. This program was preceded by the politicization of science, which incorporated popular prejudices into "scientific" theories and declared some individuals and even "racial" groups, like Jews and Gypsies, to be "valueless"; by the eugenic movement; and by the misuse of scientific hypotheses by politicians. The policy of exclusion of the "racially inferior" stood at the center of the Nazi utopia. The "euthanasia program", implemented in 1939-40, paved the way for the mass extermination of Jews and Gypsies in 1942-44. Many of those involved in the T4 program (e.g. Franz Stangl) were later involved in the operation of the death camps. Special attention is devoted to the murder of handicapped Jews. These, progressively excluded from the public welfare system and from the medical institutions, were concentrated in 1939-40 in special Jewish hospitals and later killed in the course of the "euthanasia program".

A vibrant cultural history investigating pandemics and vaccines, by bestselling author and historian Simon Schama Cities and countries engulfed by panic and death, desperate for vaccines but fearful of what inoculation may bring. This is what the world has just gone through with Covid-19. But as Simon Schama shows in his epic history of vulnerable humanity caught between the terror of contagion and the ingenuity of science, it has happened before. Characteristically, Schama's message is delivered through gripping, page-turning stories set in the eighteenth and nineteenth centuries: smallpox strikes London; cholera hits Paris; plague comes to India. Threading through the scenes of terror, suffering and hope - in hospitals and prisons, palaces, and slums - are an unforgettable cast of characters: a philosopher-playwright burning up with smallpox in a country chateau; a vaccinating doctor paying house calls in Halifax; a woman doctor in south India driving her inoculator-carriage through the stricken streets as dead monkeys drop from the trees. But we are also in the labs when great, life-saving breakthroughs happen, in Paris, Hong Kong, and Mumbai. At the heart of it all is an unsung hero: Waldemar Haffkine, a gun-toting Jewish student in Odesa turned microbiologist at the Pasteur Institute, hailed in England as "the saviour of mankind" for vaccinating millions against cholera and bubonic plague in British India while being cold-shouldered by the medical establishment of the Raj. Creator of the world's first mass production line of vaccines in Mumbai, he is tragically brought down in an act of shocking injustice. Foreign Bodies crosses borders between east and west, Asia and Europe, the worlds of rich and poor, politics and science. Its thrilling story carries with it the credo of its author on the interconnectedness of humanity and nature; of the powerful and the people. Ultimately, Schama says, as we face the challenges of our times together, "there are no foreigners, only familiars."

A New York Times Book Review Editors’ Choice Named a Best Book of the Year by Bloomberg (Chosen by Philip Tetlock), Booklist ’s Top 10 Science Books of the Year, and Shortlisted for Physics World ’s Book of the Year A Major Biography of the Nobel Prize–Winning Physicist, Enrico Fermi, a Leading Architect of the Atomic Age Enrico Fermi is unquestionably among the greats of the world’s physicists, the most famous Italian scientist since Galileo. Called “the Pope” by his peers, he was regarded as infallible in his instincts and research. His discoveries changed our world; they led to weapons of mass destruction and conversely to life-saving medical interventions. This unassuming man struggled with issues relevant today, such as the threat of nuclear annihilation and the relationship of science to politics. Fleeing Fascism and anti-Semitism, Fermi became a leading figure in America’s most secret project: building the atomic bomb. An examination of the human dramas that touched Fermi’s life as well as a thrilling history of scientific innovation in the twentieth century, this is the comprehensive biography that Fermi deserves.

Nobelist Eric Kandel's account of how his personal quest to understand memory intersected with the emergence of a new science. In Search of Memory relates the astonishing story of how four different and distinct disciplinesbehaviorist psychology, cognitive psychology, neuroscience, and molecular biologyconverged into a powerful new science of mind. Through its profound insights into thought, perception, action, recollection, and mental illness, this new science is revolutionizing our understanding of learning and memory while simultaneously showing great promise for more effective healing. The narrative follows Eric R. Kandel through the last five decades, focusing on Vienna, where he became fascinated with memory. With intrepid scientific ardor, Kandel was captivated first by history and psychoanalysis, then by neurobiology, and finally by the biological processes of memory. His resulting, multifaceted perspective was the foundation for his path-breaking research that will continue to dominate modern thoughtnot only in science but in culture at large. 50 illustrations.

From Pulitzer Prize-winning Washington Post reporter Eli Saslow, a powerful portrait of a country grappling with the pandemic, told through voices of people from all across America The Covid-19 pandemic was a world-shattering event, affecting everyone in the nation. From its first ominous stirrings, renowned journalist Eli Saslow began interviewing a cross-section of Americans, capturing their experiences in real time: An exhausted and anguished EMT risking his life in New York City; a grocery store owner feeding his neighborhood for free in locked-down New Orleans; an overwhelmed coroner in Georgia; a Maryland restaurateur forced to close his family business after forty-six years; an Arizona teacher wrestling with her fears and her obligations to her students; rural citizens adamant that the whole thing is a hoax, and retail workers attacked for asking people to wear masks; patients struggling to breathe and doctors desperately trying to save them. Through Saslow's masterful, empathetic interviewing, we are given a kaleidoscopic picture of a people dealing with the unimaginable. These deeply personal accounts make for cathartic reading, as we see Americans at their worst, and at their resilient best.

Essays by Oliver Sacks, Jonathan Miller, Stephen Jay Gould, Daniel J. Kevles, & R.C. Lewontin explore forgotten and neglected aspects of the history of science.

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In 1932, world-renowned physicist Wolfgang Pauli had already done the work that would win him the 1945 Nobel Prize. He was also suffering after a series of troubling personal events. He was drinking heavily, quarrelling frequently, and experiencing powerful, disturbing dreams. Pauli turned to C. G. Jung for help, forging an extraordinary intellectual conjunction not just between a physicist and a psychologist but between physics and psychology. As their acquaintance developed, Jung and Pauli discussed the nature of dreams and their relation to reality, finding surprising common ground between depth psychology and quantum physics and profoundly influencing each other's work. This portrait of an incredible friendship will fascinate readers interested in psychology, science, creativity, and genius.