From number one New York Times bestselling author Michael Pollan, a radical challenge to how we think about drugs, and an exploration into the powerful human attraction to psychoactive plants--and the equally powerful taboos Of all the things humans rely on plants for--sustenance, beauty, medicine, fragrance, flavor, fiber--surely the most curious is our use of them to change consciousness: to stimulate or calm, fiddle with or completely alter, the qualities of our mental experience. Take coffee and tea: People around the world rely on caffeine to sharpen their minds. But we do not usually think of caffeine as a drug, or our daily use as an addiction, because it is legal and socially acceptable. So, then, what is a "drug"? And why, for example, is making tea from the leaves of a tea plant acceptable, but making tea from a seed head of an opium poppy a federal crime? In This Is Your Mind on Plants , Michael Pollan dives deep into three plant drugs--opium, caffeine, and mescaline--and throws the fundamental strangeness, and arbitrariness, of our thinking about them into sharp relief. Exploring and participating in the cultures that have grown up around these drugs while consuming (or, in the case of caffeine, trying not to consume) them, Pollan reckons with the powerful human attraction to psychoactive plants. Why do we go to such great lengths to seek these shifts in consciousness, and then why do we fence that universal desire with laws and customs and fraught feelings? In this unique blend of history, science, and memoir, as well as participatory journalism, Pollan examines and experiences these plants from several very different angles and contexts, and shines a fresh light on a subject that is all too often treated reductively--as a drug, whether licit or illicit. But that is one of the least interesting things you can say about these plants, Pollan shows, for when we take them into our bodies and let them change our minds, we are engaging with nature in one of the most profound ways we can. Based in part on an essay published almost twenty-five years ago, this groundbreaking and singular consideration of psychoactive plants, and our attraction to them through time, holds up a mirror to our fundamental human needs and aspirations, the operations of our minds, and our entanglement with the natural world.

From the great popularizer of alternative medicine, here is a collection of essays about his travels to South America in the early 1970s in search of information on altered states of consciousness, drug use in other cultures, and other matters having to do with the complementarity of mind and body. Andrew Weil's experiences during this time laid the foundation for his mission to restore the connection between medicine and nature. In The Marriage of the Sun and Moon, now updated with a new preface by the author, the esteemed Dr. Weil attempts to empower patients to take fuller charge of their destinies.

In its decades-long effort to assure the safety, efficacy, and security of medicines and other products, the Food and Drug Administration has struggled with issues of funding, proper associations with industry, and the balance between consumer choice and consumer protection. Today, these challenges are compounded by the pressures of globalization, the introduction of novel technologies, and fast-evolving threats to public health. With essays by leading scholars and government and private-industry experts, FDA in the Twenty-First Century addresses perennial and new problems and the improvements the agency can make to better serve the public good. The collection features essays on effective regulation in an era of globalization, consumer empowerment, and comparative effectiveness, as well as questions of data transparency, conflicts of interest, industry responsibility, and innovation policy, all with an emphasis on pharmaceuticals. The book also intervenes in the debate over off-label drug marketing and the proper role of the FDA before and after a drug goes on the market. Dealing honestly and thoroughly with the FDA's successes and failures, these essays rethink the structure, function, and future of the agency and the effect policy innovations may have on regulatory institutions abroad.

Vaccines offer the best hope for controlling diseases and could dramatically improve health in poor countries. But developers have little incentive to undertake the costly and risky research needed to develop vaccines. This is partly because the potential consumers are poor, but also because governments drive down prices." "In Strong Medicine, Michael Kremer and Rachel Glennerster offer an innovative yet simple solution to this worldwide problem: "Pull" programs to stimulate research. Here's how such programs would work. Funding agencies would commit to purchase viable vaccines if and when they were developed. This would create the incentives for vaccine developers to produce usable products for these neglected diseases. Private firms, rather than funding agencies, would pick which research strategies to pursue. After purchasing the vaccine, funders could distribute it at little or no cost to the afflicted countries

This book is intended for medical students and advanced undergraduates such as physicists and mathematicians with inter-disciplinary interests, biophysicists, medical physicists, applied mathematicians and others who wish to understand medicine in mathematical terms as well as current mathematical applications in physiology and medicine. The mathematical presentation is clear and self-contained.This book, representing 15 years of work at RAND Corporation and USC on chemotherapy, pharmacokinetics and nuclear medicine, attempts to direct medical scientists towards mathematical aspects of problems in medicine. The book begins with an introduction to compartmental models and matrix theory, highlighting the advantages of the approach. Discussions on how questions in observations and testing lead to multi-point boundary value problems are presented. The potentials of the digital computer in the bio-medical field are examined. A new approach -- dynamic programming -- to overcome clinical constraints is covered in detail. The reader should obtain a broad impression of where future research opportunities in the biochemical field lie.