Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer, yet her cells--taken without her knowledge--became one of the most important tools in medicine. The first "immortal" human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer and viruses; helped lead to in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks is buried in an unmarked grave. Her family did not learn of her "immortality" until more than twenty years after her death, when scientists began using her husband and children in research without informed consent. The story of the Lacks family is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of--From publisher description.

"Since the first edition of Who Shall Live? (1974), over 100,000 students, teachers, physicians, and general readers from more than a dozen fields have found this book to be a reader-friendly, authoritative introduction to economic concepts applied to health and medical care. Health care is by far the largest industry in the United States. It is three times larger than education and five times as large as national defense. In 2001, Americans spent over 12,500 per person for hospitals, physicians, drugs and other health care services and goods. Other high-income democracies spend one third less, enjoy three more years of life expectancy, and have more equal access to medical care. In this book, each of the chapters of the original edition is followed by supplementary readings on such subjects as: "Social Determinants of Health: Caveats and Nuances", "The Structure of Medical Education - It's Time For a Change", and "How to Save 1 Trillion Out of Health Care". The ten years following publication of the 2nd expanded edition in 2011 were arguably more turbulent for US health and health care than any other ten-year period since World War II. They span the implementation of the Affordable Care Act, the deepening opioid epidemic, and the physical, psychological, and socio-economic traumas of the Covid-19 pandemic. An important new contribution to this book is to describe and analyze the changes in five sections: "The Affordable Care Act and the Uninsured", "Health care Expenditures", Health Outcomes", "The Covid-19 Pandemic", and "Health and Politics". This part includes 24 tables and figures. This book will be welcomed by students, professionals, and life-long learners to gain increased understanding of the relation between health, economics, and social choice"--

All investigators funded by the National Institutes of Health are now required to receive training about the ethics of clinical research. Based on a course taught by the editors at NIH, Ethical and Regulatory Aspects of Clinical Research is the first book designed to help investigators meet this new requirement. The book begins with the history of human subjects research and guidelines instituted since World War II. It then covers various stages and components of the clinical trial process: designing the trial, recruiting participants, ensuring informed consent, studying special populations, and conducting international research. Concluding chapters address conflicts of interest, scientific misconduct, and challenges to the IRB system. The appendix provides sample informed consent forms. This book will be used in undergraduate courses on research ethics and in schools of medicine and public health by students who are or will be carrying out clinical research. Professionals in need of such training and bioethicists also will be interested.

Book by Rosner, Fred

To find more information on Rowman & Littlefield titles, please visit us at www.rowmanlittlefield.com.

In recent decades, American medicine has become increasingly politicized and politics has become increasingly medicalized. Behaviors previously seen as virtuous or wicked, wise or unwise are now dealt with as healthy or sick--unwanted behaviors to be controlled as if they were health issues. The modern penchant for transforming human problems into diseases and judicial sanctions into treatments, replacing the rule of law with the rule of medical discretion, leads to the creation of a type of government social critic Thomas Szasz calls pharmacracy. Medicalizing troublesome behaviors and social problems is tempting to voters and politicians alike: it panders to the people by promising to satisfy their needs for dependence on medical authority and offers easy self-aggrandizement to politicians as the dispensers of more and better health care. Thus, the people gain a convenient scapegoat, enabling them to avoid personal responsibility for their behavior. The government gains a rationale for endless and politically expedient wars against social problems defined as public health emergencies. The health care system gains prestige, funding, and bureaucratic power that only an alliance with the political system can provide. However, Szasz warns, the creeping substitution of pharmacracy for democracy--private medical concerns increasingly perceived as requiring a political response--inexorably erodes personal freedom and dignity. Pharmacracy: Medicine and Politics in America is a clear and convincing presentation of this hidden danger, all too often ignored in our health care debates and avoided in our political contests.

Timely and provocative essays on bioethical questions brought to the forefront by the bioterrorist threat. The war on terrorism and the threat of chemical and biological weapons have brought a new urgency to already complex moral and bioethical questions. In the Wake of Terror presents thought-provoking essays on many of the troubling issues facing American society, written by experts from the fields of medicine, health care policy, law, political science, history, philosophy, and theology. One of the first potential casualties of catastrophic circumstances is civil liberties. In the past, medical experiments conducted for national security purposes have violated ethical standards, and this book questions whether current policy provides sufficient safeguards against further abuses. It also focuses on public health issues, offering contrasting views on the extent to which civil authorities should be allowed to restrict freedom of movement in the name of national security and debating whether aggressive public health interventions improve public confidence and cooperation or detract from them. A major area of concern is preparedness for future terrorist attacks. Chapters are devoted to ethical issues involved in the development, distribution, and rationing of vaccines and antidotes; resource allocation and medical triage; the moral duties of emergency health workers and other first responders; and the obligations of private entities such as managed care organizations and pharmaceutical companies. Contributors also address the implications of terrorism for our health insurance system and the role of genetic advances in bioterrorism. Underlying all of these issues, the authors argue, is the need to maintain a spirit of social solidarity, which can in turn only be achieved if preparations are publicly acknowledged and generally regarded as both prudent and fair.

Integrating theory with realistic case studies, this book examines the practical application of moral theory in clinical decision-making. With forty composite cases based on actual clinical experiences, the author describes key moral problems raised by modern medicine. He then demonstrates how these dilemmas can be resolved using a problem-solving framework termed pluralistic casuistry. This approach is pluralistic in that it accepts the relevance of many different moral grounds, drawn from different traditional moral theories, each of which may seem self-contained and hence in conflict with other claims. Consequently, the author stresses the need to achieve a synthesis of these traditional moral theories, rather than treating them as competitors. His approach is casuistrical in the sense that it considers the important differences between the cases at issue and applies the different moral appeals in different ways. The richly detailed case studies will challenge readers, clarify the ethical issues involved, and indicate how theory and practice can be integrated. Containing a multiplicity of factors faced in clinical crises, they are ideal for group discussions concerning the ways in which theory relates to actual life-or-death situations.

12 essays describe the anger and frustration patients and families often feel towards the health care system.

The International Society for Science and Religion has selected Matters of Life and Death as an element of the ISSR Library. The mission of the ISSR Library is "to provide a comprehensive resource for scholars, students, and interested lay readers in the area of science and the human spirit."The incredible medical breakthroughs of today, like genetic engineering, in-vitro fertilizations, and cloning have transformed long-held beliefs on the nature of both life and death, raising difficult moral and religious questions. In Matters of Life and Death Elliot Dorff thoroughly addresses this unavoidable confluence of medical technology and Jewish law and ethics. Elliot N. Dorff, Rabbi (Jewish Theological Seminary), PhD (Columbia University), is rector and Sol and Anne Dorff Distinguished Professor of Philosophy at the American Jewish University (formerly the University of Judaism) in Los Angeles. Among the twelve books he has written are four award-winning books on Jewish ethics and law published by The Jewish Publication Society: Matters of Life and Death (1998) on Jewish medical ethics; To Do the Right and the Good (2002) on Jewish social ethics; Love Your Neighbor and Yourself on Jewish personal ethics; and For the Love of God and People: A Philosophy of Jewish Law (2007). He has also edited 10 books, including Contemporary Jewish Ethics and Morality (Oxford, 1995) and Contemporary Jewish Theology (Oxford, 1999), co-edited by Louis Newman, who also co-edited with Dorff the first three volumes of the Jewish Choices, Jewish Voices series. Since 1984, Rabbi Dorff has served on the Rabbinical Assembly's Committee on Jewish Law and Standards, and has served as its Chair since 2007. He has also served on several federal advisory commissions dealing with the ethics of health care, sexual responsibility, and research on human subjects. He is a member of the State of California's Ethics Committee on embryonic stem cell research. He is married to Marlynn, and they have four children and seven grandchildren.

This book analyzes the major issues of research ethics through a careful review of the treatment in official policies on research ethics developed throughout the world (especially North America, Western Europe, and the Pacific Rim). Among the issues covered are animal research, research on human subjects, epidemiological research, genetic research, reproductive research, research on vulnerable subjects, clinical trials, drug approval and the research process, and research on women and minorities. Brody also evaluates the content and the methods of developing these policies in light of his philosophical position of pluralistic casuistry. This is the only book that analyzes all the major issues in research ethics. It is the only book which deals with these issues from an international perspective rather than just a US perspective. Major official policies from important research-intensive countries are reprinted in the appendix (close to 200 plates of otherwise difficult material).

THE AMBASSADOR takes place in Europe a hundred years from now. It is a time when the European Union is the supreme leader of the free world, the main challenger to China, with the USA trailing behind. Scientific advance has brought the ability to beat disease and ageing - not by medicine alone but more fundamentally, by gene therapy. In THE AMBASSADOR, Bill Strether is sent by the American President to the UK to represent his country which, captured by fundamentalists, has banned the medical advances taken for granted in his new home. Although he harbours doubts about its ethics, he finds the official genetic programme breathtaking and impossible to condemn. THE AMBASSADOR is an extraordinarily persuasive account of how the world could be. The results could be chilling, even terrifying. Scientific discovery is both Pandora's box and Ali Baba's cave. When faced with the astonishing array of choices offered to us by the new genetic knowledge, how do we choose?

1. GENERAL The term "diagnostics" refers to the general theory of diagnosis, not to the study of specific diagnoses but to their general framework. It borrows from different sciences and from different philosophies. Traditionally, the general framework of diagnostics was not distinguished from the framework of medicine. It was not taught in special courses in any systematic way; it was not accorded special attention: students absorbed it intuitively. There is almost no comprehensive study of diagnostics. The instruction in diagnosis provided in medical schools is exclusively specific. Clinical instruction includes (in addition to vital background information, such as anatomy and physiology) specific instruction in nosology, the theory and classification of diseases, and this includes information on diagnoses and prognoses of diverse diseases. What is the cause of the neglect of diagnostics, and of its integrated teaching? The main cause may be the prevalence of the view of diagnostics as part-and parcel of nosology. In this book nosology is taken as a given, autonomous field of study, which invites almost no comments; we shall freely borrow from it a few important general theses and a few examples. We attempt to integrate here three studies: ll of the way nosology is used in the diagnostic process; of the diagnostic process as a branch of applied ethics; ~ of the diagnostic process as a branch of social science and social technology.

"When it comes to morality as it is practiced in medicine, Brody makes clear that the ethical issues are never as simple as black and white - that there are myriad factors and fine nuances that can and should challenge decision making as it is commonly practiced in difficult medical cases. In this collection, delving thoughtfully and systematically into methodology, research ethics, clinical ethics, and Jewish medical ethics, he tackles thorny life-and-death questions head-on and fearlessly. He casts a light into all the corners of end-of-life decisions - a field in which he has exemplary credentials - while illuminating a new understanding of morality and ethics." "The introduction outlines much of Brody's approach, defines the terminology used, and contrasts his ethical positions with much of the competing literature, Taking Issue will be invaluable to students and scholars in medical ethics, bioethics, and the philosophy of medicine." "Baruch A. Brody is the Leon Jaworski Professor Biomedical Ethics and director of the Center for Medical Ethics and Health Policy at Baylor College of Medicine. He is also a professor of philosophy at Rice University and director of the Ethics program at the Methodist Hospital."--BOOK JACKET