Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer, yet her cells--taken without her knowledge--became one of the most important tools in medicine. The first "immortal" human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer and viruses; helped lead to in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks is buried in an unmarked grave. Her family did not learn of her "immortality" until more than twenty years after her death, when scientists began using her husband and children in research without informed consent. The story of the Lacks family is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of--From publisher description.

"The extraordinary story of the Nazi-era scientific genius who discovered how cancer cells eat-and what it means for how we should. The Nobel laureate Otto Warburg-a cousin of the famous finance Warburgs-was widely regarded in his day as one of the most important biochemists of the twentieth century, a man whose research was integral to humanity's understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it"--

The two companies had agreed that the CEPH would supply Millennium with a store of genetic material collected from a large number of French families, and Millennium would supply funding and expertise in new technologies to accelerate the identification of the genes, terms that the French government had approved. But in early 1994, just as the collaboration was to begin, the French government abruptly called a halt.

Vaccines offer the best hope for controlling diseases and could dramatically improve health in poor countries. But developers have little incentive to undertake the costly and risky research needed to develop vaccines. This is partly because the potential consumers are poor, but also because governments drive down prices." "In Strong Medicine, Michael Kremer and Rachel Glennerster offer an innovative yet simple solution to this worldwide problem: "Pull" programs to stimulate research. Here's how such programs would work. Funding agencies would commit to purchase viable vaccines if and when they were developed. This would create the incentives for vaccine developers to produce usable products for these neglected diseases. Private firms, rather than funding agencies, would pick which research strategies to pursue. After purchasing the vaccine, funders could distribute it at little or no cost to the afflicted countries

In his fascinating new book, Jonathan D. Moreno investigates the deeply intertwined worlds of cutting-edge brain science, U.S. defense agencies, and a volatile geopolitical landscape where a nation's weaponry must go far beyond bombs and men. The first-ever exploration of the connections between national security and brain research, Mind Wars: Brain Research and National Defense reveals how many questions crowd this gray intersection of science and government and urges us to begin to answer them. From neuropharmacology to neural imaging to brain-machine interface devices that relay images and sounds between human brains and machines, Moreno shows how national security entities seek to harness the human nervous system in a multitude of ways as a potent weapon against the enemy soldier. Moreno charts such projects as monkeys moving robotic arms with their minds, technology to read the brain’s thought patterns at a distance, the development of "anti-sleep" drugs to enhance soldiers’ battle performance and others to dampen their emotional reactions to the violence, and advances that could open the door to "neuroweapons"—virus-transported molecules to addle the brain. "As new kinds of weapons are added to the arsenal already at the disposal of fallible human leaders," Moreno writes, "we need to find new ways to address the problem"--of the ethical military application of so powerful and intimate a science. This book is the first step in confronting the quandaries inherent in this partnership of government and neuroscience, serves as a compelling wake-up call for scientists and citizens, and suggests that, with imagination, we might meet the needs of both security and civil liberty.

This book analyzes the major issues of research ethics through a careful review of the treatment in official policies on research ethics developed throughout the world (especially North America, Western Europe, and the Pacific Rim). Among the issues covered are animal research, research on human subjects, epidemiological research, genetic research, reproductive research, research on vulnerable subjects, clinical trials, drug approval and the research process, and research on women and minorities. Brody also evaluates the content and the methods of developing these policies in light of his philosophical position of pluralistic casuistry. This is the only book that analyzes all the major issues in research ethics. It is the only book which deals with these issues from an international perspective rather than just a US perspective. Major official policies from important research-intensive countries are reprinted in the appendix (close to 200 plates of otherwise difficult material).