"A brilliant and brave investigation by Michael Pollan, author of five New York Times best sellers, into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into the experience of various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both struggle and beauty, we can do our best to be fully present and find meaning in our lives"--

"After years of battling uncontrollable addiction, I have achieved the supposedly impossible: complete freedom from craving." Dr. Olivier Ameisen was a brilliant cardiologist on the staff at one of America’s top teaching hospitals and running his own successful practice when he developed a profound addiction to alcohol. He broke bones with no memory of falling; he nearly lost his kidneys; he almost died from massive seizures during acute withdrawal. He gave up his flourishing practice and, fearing for his life, immersed himself in Alcoholics Anonymous, rehab, therapy, and a variety of medications. Nothing worked. So he did the only thing he could: he took his treatment into his own hands. Searching for a cure for his deadly disease, he happened upon baclofen, a muscle relaxant that had been used safely for years as a treatment for various types of muscle spasticity, but had more recently shown promising results in studies with laboratory animals addicted to a wide variety of substances. Dr. Ameisen prescribed himself the drug and experimented with increasingly higher dosages until he finally reached a level high enough to leave him free of any craving for alcohol. That was more than five years ago. Alcoholism claims three hundred lives per day in the United States alone; one in four U.S. deaths is attributable to alcohol, tobacco, or illegal drugs. Baclofen, as prescribed under a doctor’s care, could possibly free many addicts from tragic and debilitating illness. But as long as the medical and research establishments continue to ignore a cure for one of the most deadly diseases in the world, we won’t be able to understand baclofen’s full addiction-treatment potential. The End of My Addiction is both a memoir of Dr. Ameisen’s own struggle and a groundbreaking call to action—an urgent plea for research that can rescue millions from the scourge of addiction and spare their loved ones the collateral damage of the disease.