Soul Made Flesh is the remarkable untold story of a dramatic turning point in history, the exciting discovery of how the human brain works. In an unprecedented examination of how the secrets of the brain were revealed in seventeenth-century England, award-winning author Carl Zimmer tells an extraordinary tale that unfurls against a deadly backdrop of civil war, plague, and the Great Fire of London. At the beginning of that turbulent century, no one knew how the brain worked or even what it looked like intact. By the century's close, the science of the brain had taken root, helping to overturn many of the most common misconceptions and dominant philosophies about man, God, and the universe. Presiding over the rise of this new scientific paradigm was the founder of modern neurology, Thomas Willis, a fascinating, sympathetic, even heroic figure who stands at the center of an extraordinary group of scientists and philosophers known as the Oxford circle. Chronicled here in vivid detail are their groundbreaking revelations and often gory experiments that first enshrined the brain as the chemical engine of reason, emotion, and madness, indeed as the very seat of the human soul. Called 'as fine a science essayist as we have' by The New York Times, Zimmer tells the story of this scientific revolution through the lives of a colorful array of alchemists, mystics, utopians, spies, revolutionaries, and kings. He recreates the religious, ethical, and scientific struggles involved in the pioneering autopsies of the brain carried out by Thomas Willis; the discovery of the circulation of blood by William Harvey and his flight from London with his besieged king, Charles I; René Descartes's persecution by Catholics and Protestants alike for his views of the brain and soul; and the experiments and personal dramas of gifted men who forever changed the way science is practiced as they simultaneously upended our view of our human selves and our place in the world. In this distant mirror to our own time of continuing scientific revolution and worldwide social upheaval, Zimmer brings to life the painstaking, innovative discoveries of Willis and his contemporaries, the taproots of the amazing work of today's neuroscientists, who continue to explore the brain, revealing the hidden workings of emotions, memories, and consciousness. Graced with beautiful illustrations by Christopher Wren, Soul Made Flesh conveys a contagious appreciation for the wonder of the brain, its structure, its many marvelous functions, and the implications for human identity, mind, and morality. It is the definitive history of the dawn of a world-changing science and attitude, the age of the brain and modern consciousness.

"This book will challenge you to rethink your vision of a good life. With sharp insights and lucid prose, Paul Bloom makes a captivating case that pain and suffering are essential to happiness. It's an exhilarating antidote to toxic positivity." --Adam Grant, #1 New York Times bestselling author of Think Again and host of the TED podcast WorkLife One of Behavioral Scientist's "Notable Books of 2021" From the author of Against Empathy, a different kind of happiness book, one that shows us how suffering is an essential source of both pleasure and meaning in our lives Why do we so often seek out physical pain and emotional turmoil? We go to movies that make us cry, or scream, or gag. We poke at sores, eat spicy foods, immerse ourselves in hot baths, run marathons. Some of us even seek out pain and humiliation in sexual role-play. Where do these seemingly perverse appetites come from? Drawing on groundbreaking findings from psychology and brain science, The Sweet Spot shows how the right kind of suffering sets the stage for enhanced pleasure. Pain can distract us from our anxieties and help us transcend the self. Choosing to suffer can serve social goals; it can display how tough we are or, conversely, can function as a cry for help. Feelings of fear and sadness are part of the pleasure of immersing ourselves in play and fantasy and can provide certain moral satisfactions. And effort, struggle, and difficulty can, in the right contexts, lead to the joys of mastery and flow. But suffering plays a deeper role as well. We are not natural hedonists--a good life involves more than pleasure. People seek lives of meaning and significance; we aspire to rich relationships and satisfying pursuits, and this requires some amount of struggle, anxiety, and loss. Brilliantly argued, witty, and humane, Paul Bloom shows how a life without chosen suffering would be empty--and worse than that, boring.

Nobelist Eric Kandel's account of how his personal quest to understand memory intersected with the emergence of a new science. In Search of Memory relates the astonishing story of how four different and distinct disciplinesbehaviorist psychology, cognitive psychology, neuroscience, and molecular biologyconverged into a powerful new science of mind. Through its profound insights into thought, perception, action, recollection, and mental illness, this new science is revolutionizing our understanding of learning and memory while simultaneously showing great promise for more effective healing. The narrative follows Eric R. Kandel through the last five decades, focusing on Vienna, where he became fascinated with memory. With intrepid scientific ardor, Kandel was captivated first by history and psychoanalysis, then by neurobiology, and finally by the biological processes of memory. His resulting, multifaceted perspective was the foundation for his path-breaking research that will continue to dominate modern thoughtnot only in science but in culture at large. 50 illustrations.

Astrophysicist and author Mario Livio investigates perhaps the most human of all our characteristics—curiosity—in this “lively, expert, and definitely not dumbed-down account” ( Kirkus Reviews ) as he explores our innate desire to know why . Experiments demonstrate that people are more distracted when they overhear a phone conversation—where they can know only one side of the dialogue—than when they overhear two people talking and know both sides. Why does half a conversation make us more curious than a whole conversation? “Have you ever wondered why we wonder why? Mario Livio has, and he takes you on a fascinating quest to understand the origin and mechanisms of our curiosity. I thoroughly recommend it.” (Adam Riess, Nobel Prize Winner in Physics, 2011). Curiosity is not only at the heart of mystery and suspense novels, it is also essential to other creative endeavors, from painting to sculpture to music. It is the principal driver of basic scientific research. Even so, there is still no definitive scientific consensus about why we humans are so curious, or about the mechanisms in our brain that are responsible for curiosity. In the ever-fascinating Why? Livio interviewed scientists in several fields to explore the nature of curiosity. He examined the lives of two of history’s most curious geniuses, Leonardo da Vinci and Richard Feynman. He also talked to people with boundless curiosity: a superstar rock guitarist who is also an astrophysicist; an astronaut with degrees in computer science, biology, literature, and medicine. What drives these people to be curious about so many subjects? An astrophysicist who has written about mathematics, biology, and now psychology and neuroscience, Livio has firsthand knowledge of his subject which he explores in a lucid, entertaining way that will captivate anyone who is curious about curiosity.

Neuroscience is one of the scientific fields where progress in the 20th century has been spectacular. With the coming of the new millennium, it is appropriate to look at some of the advances and the neurologists who helped to produce them. The original contributions in this volume reflect the background against which the rapid advances have taken place in the past 100 years.