This book is the first devoted to modern biology s innovators and iconoclasts: men and women who challenged prevailing notions in their fields. Some of these scientists were Nobel Prize winners, some were considered cranks or gadflies, some were in fact wrong. The stories of these stubborn dissenters are individually fascinating. Taken together, they provide unparalleled insights into the role of dissent and controversy in science and especially the growth of biological thought over the past century. Each of the book s nineteen specially commissioned chapters offers a detailed portrait of the intellectual rebellion of a particular scientist working in a major area of biology--genetics, evolution, embryology, ecology, biochemistry, neurobiology, and virology as well as others. An introduction by the volume s editors and an epilogue by R. C. Lewontin draw connections among the case studies and illuminate the nonconforming scientist s crucial function of disturbing the comfort of those in the majority. By focusing on the dynamics and impact of dissent rather than on winners who are credited with scientific advances, the book presents a refreshingly original perspective on the history of the life sciences. Scientists featured in this volume: Alfred Russel Wallace Hans Driesch Wilhelm Johannsen Raymond Arthur Dart C. D. Darlington Richard Goldschmidt Barbara McClintock Oswald T. Avery Roger Sperry Leon Croizat Vero Copner Wynne-Edwards Peter Mitchell Howard Temin Motoo Kimura William D. Hamilton Carl Woese Stephen Jay Gould Thelma Rowell Daniel S. Simberloff "

The stories of nineteen scientists--some famous, some forgotten--who stubbornly challenged assumptions and icons in the life sciences This book is the first devoted to modern biology's innovators and iconoclasts: men and women who challenged prevailing notions in their fields. Some of these scientists were Nobel Prize winners, some were considered cranks or gadflies, some were in fact wrong. The stories of these stubborn dissenters are individually fascinating. Taken together, they provide unparalleled insights into the role of dissent and controversy in science and especially the growth of biological thought over the past century. Each of the book's nineteen specially commissioned chapters offers a detailed portrait of the intellectual rebellion of a particular scientist working in a major area of biology--genetics, evolution, embryology, ecology, biochemistry, neurobiology, and virology as well as others. An introduction by the volume's editors and an epilogue by R. C. Lewontin draw connections among the case studies and illuminate the nonconforming scientist's crucial function of disturbing the comfort of those in the majority. By focusing on the dynamics and impact of dissent rather than on "winners" who are credited with scientific advances, the book presents a refreshingly original perspective on the history of the life sciences. Scientists featured in this volume: Alfred Russel Wallace Hans Driesch Wilhelm Johannsen Raymond Arthur Dart C. D. Darlington Richard Goldschmidt Barbara McClintock Oswald T. Avery Roger Sperry Leon Croizat Vero Copner Wynne-Edwards Peter Mitchell Howard Temin Motoo Kimura William D. Hamilton Carl Woese Stephen Jay Gould Thelma Rowell Daniel S. Simberloff

"America's most interesting and important essayist." --Eric Kandel, Nobel Prize-winning author of The Age of Insight "[Gerald Weissmann] bridges the space between science and the humanities, and particularly between medicine and the muses, with wit, erudition, and, most important, wisdom." --Adam Gopnik Epigenetics, which attempts to explain how our genes respond to our environment, is the latest twist on the historic nature vs. nurture debate. In addressing this and other controversies in contemporary science, Gerald Weissmann taps what he calls "the social network of Western Civilization," including the many neglected women of science: from the martyred Hypatia of Alexandria, the first woman scientist, to the Nobel laureates Marie Curie, Christiane Nüsslein-Volhard, and Elizabeth Blackburn, among other luminaries in the field. Always instructive and often hilarious, this is a one-volume introduction to modern biology, viewed through the lens of contemporary mass media and the longer historical tradition of the Scientific Revolution. Whether engaging in the healthcare debate or imagining the future prose styling of the scientific research paper in the age of Twitter, Weissmann proves himself as an incisive cultural critic and satirist. Gerald Weissmann (August 7, 1930 - July 10, 2019) was a physician, scientist, editor, and essayist whose collections include The Fevers of Reason: New and Selected Essays ; Epigenetics in the Age of Twitter: Pop Culture and Modern Science ; Mortal and Immortal DNA: Science and the Lure of Myth ; and Galileo's Gout: Science in an Age of Endarkenment .

This book commemorates the eclectic intellectual life of scientist and artist Walter Gilbert. It presents all of his most influential works throughout his scientific career. His scientific explorations covered a broad spectrum of fields: theoretical physics; molecular biology, from finding messenger RNA to elucidating the regulation of the lac operon to understanding DNA replication; gene evolution and origin of life; genomics; bioinformatics; and beyond. He created widely used concepts such as 'Exon', 'Intron' and 'RNA World'. Eleven reflective essays by Gilbert are included for the first time, discussing both his scientific studies and anecdotes from his own life. These firsthand accounts record the historical and intellectual contexts for his most monumental scientific discoveries, including his Nobel Prize-winning sequencing method. Memorial chapters, contributed by Gilbert Laboratory alumni, describe the passion, ambition, and efforts of Gilbert and several generations of young scientists under his leadership. Finally, the book collects a few fine pieces of artwork created by Gilbert in recent years. It documents a life of genius and creativity that could inspire others for years to come.