"This successor volume to The Singularity Is Near explores how technology will refashion the human race in the decades to come. In this entirely new book, Ray Kurzweil brings a fresh perspective to advances in the singularity-assessing the progress of many of his predictions and examining the novel advancements that, in the near future, will bring a revolution in knowledge and an expansion of human potential. Among the topics he discusses are rebuilding the world atom by atom with devices like nanobots; radical life extension beyond the current age limit of 120; reinventing intelligence by expanding biological capacity with nonbiological intelligence in the cloud; how life is improving with declines in poverty and violence; and the growth of technologies that can be applied to everything from clothes to building materials to growing human organs. He also considers the potential perils of biotechnology, nanotechnology, and artificial intelligence, including such topics as how AI will impact unemployment and the safety of autonomous cars, and "After Life" technology, which will reanimate people who have passed away through a combination of data and DNA"--

Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

"This capstone novel in Library of America's Bernard Malamud edition brings together his three final novels: The Tenants, about the growing tension between two male writers--one Jewish, the other Black--who are the only inhabitants of a crumbling Manhattan tenement house; Dubin's Lives, a revealing study in the perils and promise of love in middle age thought to be Malamud's most autobiographical work; and God's Grace, a postapocalyptic tale of upended evolution in which redemption depends on the lone human survivor's ability to find common ground with a talking chimp. Edited by Malamud's definitive biographer, the volume is rounded out with thirteen masterful short stories and the memoir 'Long Work, Short Life' as well as a fascinating autobiographic sketch, 'A Lost Bar-Mitzvah,' published here for the first time."--Dust jacket.

"When it comes to the phenomenon that is consciousness, there is one point on which scientists, philosophers, and artists all agree: that it feels like something to be us. Yet the fact we have subjective experience of the world remains one of nature's greatest mysteries. How is it that our mental operations are accompanied by feelings, thoughts, and a sense of self? What would a scientific investigation of our inner life look like, considering we have as little distance and perspective on it as fish do of the sea? In A World Appears, Michael Pollan traces the unmapped continent that is consciousness, bringing radically different perspectives-scientific, philosophical, literary, spiritual and psychedelic-to see what each can teach us about this central fact of life. When neuroscientists began studying consciousness in the early 1990s, they sought to explain how and why three pounds of spongy grey matter could generate a subjective point of view-assuming that the brain is the source of our felt reality. Pollan takes us to the cutting edge of the field, where scientists are entertaining more radical (and less materialist) theories of consciousness. He introduces us to "plant neurobiologists" searching for the first flicker of consciousness in plants; scientists striving to engineer feelings into AI, and psychologists and novelists seeking to capture the felt experience of our slippery stream of consciousness. In Pollan's dazzling exploration of consciousness, he discovers a world far deeper and stranger than our everyday reality. Eye-opening and mind-expanding, A World Appears takes us into the laboratories of our own minds, ultimately showing us how we might make better use of the gift of awareness to more meaningfully connect with our deepest selves"-- Provided by publisher.

These original contributions by symbiosis biologists and evolutionary theorists address the adequacy of the prevailing neo-Darwinian concept of evolution in the light of growing evidence that hereditary symbiosis, supplemented by the gradual accumulation of heritable mutation, results in the origin of new species and morphological novelty. A departure from mainstream biology, the idea of symbiosis—as in the genetic and metabolic interactions of the bacterial communities that became the earliest eukaryotes and eventually evolved into plants and animals—has attracted the attention of a growing number of scientists. These original contributions by symbiosis biologists and evolutionary theorists address the adequacy of the prevailing neo-Darwinian concept of evolution in the light of growing evidence that hereditary symbiosis, supplemented by the gradual accumulation of heritable mutation, results in the origin of new species and morphological novelty. They include reports of current research on the evolutionary consequences of symbiosis, the protracted physical association between organisms of different species. Among the issues considered are individuality and evolution, microbial symbioses, animal­bacterial symbioses, and the importance of symbiosis in cell evolution, ecology, and morphogenesis. Lynn Margulis, Distinguished Professor of Botany at the University of Massachusetts at Amherst, is the modern originator of the symbiotic theory of cell evolution. Once considered heresy, her ideas are now part of the microbiological revolution. Contributors Peter Atsatt, Richard C. Back, David Bermudes, Paola Bonfante-Fasolo, René Fester, Lynda J. Goff, Anne-Marie Grenier, Ricardo Guerrero, Robert H. Haynes, Rosmarie Honegger, Gregory Hinkle, Kwang W. Jeon, Bryce Kendrick, Richard Law, David Lewis, Lynn Margulis, John Maynard Smith, Margaret J. McFall-Ngai, Paul Nardon, Kenneth H. Nealson, Kris Pirozynski, Peter W. Price, Mary Beth Saffo, Jan Sapp, Silvano Scannerini, Werner Schwemmler, Sorin Sonea, Toomas H. Tiivel, Robert K. Trench, Russell Vetter