"Pharmaceutical breakthroughs such as antibiotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. Pharma introduces brilliant scientists, in-corruptible government regulators, and brave whistleblowers facing off against company executives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry's DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America's wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Relying on thousands of pages of government and corporate archives, dozens of hours of interviews with insiders, and previously classified FBI files, Posner exposes the secrets of the Sacklers' rise to power--revelations that have long been buried under a byzantine web of interlocking companies with ever-changing names and hidden owners. The unexpected twists and turns of the Sackler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. Pharma reveals how and why American drug companies have put earnings ahead of patients." -- Publisher's description

"Is chocolate heart-healthy? Does yogurt prevent type 2 diabetes? Do pomegranates help cheat death? News accounts bombard us with such amazing claims, report them as science, and influence what we eat. Yet, as Marion Nestle explains, these studies are more about marketing than science; they are often paid for by companies that sell those foods. Whether it's a Coca-Cola-backed study hailing light exercise as a calorie neutralizer, or blueberry-sponsored investigators proclaiming that this fruit prevents erectile dysfunction, every corner of the food industry knows how to turn conflicted research into big profit. As Nestle argues, it's time to put public health first. Written with unmatched rigor and insight, Unsavory Truth reveals how the food industry manipulates nutrition science--and suggests what we can do about it"--

Our fates lie in our genes and not in the stars, said James Watson, co-discoverer of the structure of DNA. But Watson could not have predicted the scale of the industry now dedicated to this new frontier. Since the launch of the multibillion-dollar Human Genome Project, the biosciences have promised miraculous cures and radical new ways of understanding who we are. But where is the new world we were promised? Now updated with a new afterword, Genes, Cells and Brains asks why the promised cornucopia of health benefits has failed to emerge and reveals the questionable enterprise that has grown out of bioethics. The authors, feminist sociologist Hilary Rose and neuroscientist Steven Rose, examine the establishment of biobanks, the rivalries between public and private gene sequencers, and the rise of stem cell research. The human body is becoming a commodity, and the unfulfilled promises of the science behind this revolution suggest profound failings in genomics itself.

Do We Still Need Doctors? is a personal account from the front lines of the moral and political battles that are reshaping America's health care system. Using compelling firsthand experiences, clinical vignettes, and moral arguments, John D. Lantos, a pediatrician, asks whether, as we proceed with the redesign of our health care system, doctors will - or should - continue to fulfill the roles and responsibilities that they have in the past. Interspersing moving personal stories of his young patients suffering from AIDS, cancer, and other chronic or terminal illnesses with his own stirring dilemmas of truth telling, creative navigation of HMO bureaucracy, and reflections on the identity crisis of medical education, Dr. Lantos reveals how changes in our health care system and new technologies are fostering new ways of understanding and responding to illness. He taps into the public's sense of wanting doctors and hospitals to do something other than what they do now and the frustrating disagreement about what they should do in the future. Do We Still Need Doctors? neither demonizes nor idealizes managed care or for-profit medicine. Instead, Dr. Lantos argues that managed care continues a trend toward rationalizing disease and streamlining treatment that doctors themselves have initiated and sustained over the last fifty years. Illness and death will always resist rationalizing, and in order to respond to them, doctors and patients alike need to re-imagine what healing is or ought to be.

All investigators funded by the National Institutes of Health are now required to receive training about the ethics of clinical research. Based on a course taught by the editors at NIH, Ethical and Regulatory Aspects of Clinical Research is the first book designed to help investigators meet this new requirement. The book begins with the history of human subjects research and guidelines instituted since World War II. It then covers various stages and components of the clinical trial process: designing the trial, recruiting participants, ensuring informed consent, studying special populations, and conducting international research. Concluding chapters address conflicts of interest, scientific misconduct, and challenges to the IRB system. The appendix provides sample informed consent forms. This book will be used in undergraduate courses on research ethics and in schools of medicine and public health by students who are or will be carrying out clinical research. Professionals in need of such training and bioethicists also will be interested.

This issues-based reference work (available in both print and electronic formats) shines a spotlight on health care policy and practice in the United States. Impassioned debates about the best solutions to health care in America have perennially erupted among politicians, scholars of public policy, medical professionals, and the general public. The fight over the Health Care Reform Act of 2010 brought to light a multitude of fears, challenges, obstacles, and passions that often had the effect of complicating rather than clarifying the debate. The discourse has never been more heated. The complex issues that animate the health care debate have forced the American public to grapple with the exigencies of the present system with regard to economic, fiscal, and monetary policy, especially as they relate to philosophical, often ideologically driven approaches to the problem. Americans have also had to examine their ideas about the relationship of the individual to and interaction with the state and the varied social and cultural beliefs about what an American solution to the problem of health care looks like. In light of the need to keep students, researchers, and other interested readers informed and up-to-date on the issues surrounding health care in the U.S., this volume uses introductory essays followed by point/counterpoint articles to explore prominent and perennially important debates, providing readers with views on multiple sides of this complex issue. Features & Benefits: The volume is divided into three sections, each with its own Section Editor: Quality of Care Debates (Dr. Jennie Kronenfeld), Economic & Fiscal Debates (Dr. Mark Zezza), and Political, Philosophical, & Legal Debates (Prof. Wendy Parmet). Sections open with a Preface by the Section Editor to introduce the broad theme at hand and provide historical underpinnings. Each Section holds 12 chapters addressing varied aspects of the broad theme of the section. Chapters open with an objective, lead-in piece (or "headnote") followed by a point article and a counterpoint article. All pieces (headnote, point article, counterpoint article) are signed. For each chapter, students are referred to further readings, data sources, and other resources as a jumping-off spot for further research and more in-depth exploration. Finally, the volume concludes with a comprehensive index, and the electronic version of the book includes search-and-browse features, as well as the ability to link to further readings cited within chapters should they be available to the library in electronic format.

"The book is readable and challenging; readers will never see psychiatry in the same way again." -- Choice Reviews Originally called mad-doctoring, psychiatry began in the seventeenth century with the establishing of madhouses and the legal empowering of doctors to incarcerate persons denominated as insane. Until the end of the nineteenth century, every relationship between psychiatrist and patient was based on domination and coercion, as between master and slave. Psychiatry, its emblem the state mental hospital, was a part of the public sphere, the sphere of coercion. The advent of private psychotherapy, at the end of the nineteenth century, split psychiatry in two: some patients continued to be the involuntary inmates of state hospitals; others became the voluntary patients of privately practicing psychotherapists. Psychotherapy was officially defined as a type of medical treatment, but actually was a secular-medical version of the cure of souls. Relationships between therapist and patient, Thomas Szasz argues, was based on cooperation and contract, as is relationships between employer and employee, or, between clergyman and parishioner. Psychotherapy, its emblem the therapist's office, was a part of the private sphere, the contract. Through most of the twentieth century, psychiatry was a house divided-half-slave, and half-free. During the past few decades, psychiatry became united again: all relations between psychiatrists and patients, regardless of the nature of the interaction between them, are now based on actual or potential coercion. This situation is the result of two major "reforms" that deprive therapist and patient alike of the freedom to contract with one another: Therapists now have a double duty: they must protect all mental patients-involuntary and voluntary, hospitalized or outpatient, incompetent or competent-from themselves. They must also protect the public from all patients. Persons designated as mental patients may be exempted from responsibility for the deleterious consequences of their own behavior if it is attributed to mental illness. The radical differences between the coercive character of mental hospital practices in the public sphere, and the consensual character of psychotherapeutic practices in the private sphere, are thus destroyed. At the same time, as the scope of psychiatric coercion expands from the mental hospital to the psychiatrist's office, its reach extends into every part of society, from early childhood to old age. Thomas Szasz is professor of psychiatry emeritus at the State University of New York Health Science Center in Syracuse, New York and Adjunct Scholar at the Cato Institute, Washington, DC. He is the author of over two dozen books in fifteen languages, including The Myth of Mental Illness and most recently, Pharmacracy: Medicine and Politics in America . "The book is readable and challenging; readers will never see psychiatry in the same way again."-- Choice "Szasz now appears to have been transformed into an ally rather than an enemy of the National Health Service general adult psychiatrist. Szasz's project has always been to argue passionately for a boundry of demarcation around the responsibility and power of psychiatry....But what saves this book from being just another mugging of psychiatry is that Szasz does raise a fundamental question at the core of our discipline. If we restricted our attention only to those clients who wanted to see a psychiatrist, and disengaged from all those who really didn't, how different might our professional practice and experience be?"-- The British Journal of Psychiatry

III Look Before You Leap: Technological Risks of Xenotransplantation -- Introduction -- Blood Sucking Host Hoppers: Zoonotic and Xenogeneic Bugs -- Theoretical Likelihood of Xenogeneic Diseases -- Practical Experience with Xenogeneic Infections -- Scientist as Lawyer: Absence of Evidence is Not Evidence of Absence -- Mi Casa Es Su Casa? Issues of Public Health Acceptability -- The U.K. Approach -- The U.S. Approach -- Stasi Medicine? - How Surveillance Can Coexist with Human Rights -- Consent, Informed or Presumed? -- Community Consent -- Life Trumps Autonomy? -- Conclusion -- IV Of Pigs and Men: Issues of Speciesism and Chimerism -- Introduction -- Are All Animals Created Equal? -- We Feel Your Pain -- Agreeing to Disagree -- Singer: Weigh Animals Like Humans -- Regan: Don't Play the Weighing Game with Life -- Frey: Humans Outweigh Animals by a Longshot -- Leahy: Weigh it in Words -- How Much Does Private Language Count? -- Physiological Signs of Pain -- Only Language Separates Us From Them -- Giving Darwin Some Respect -- Chimerism and Its Discontents -- Piled High and Deep: The Realities of Pork -- Transgressing the Pig Genome -- Transgressing Humanity -- Transgressive Psychology -- Conclusion: No Revolution Likely on the Animal Phann -- V The Right to Life: Society's Obligation to Provide Health Care and Xenotransplantation -- Introduction -- Ought Implies Kant -- Berlin's Polarization and the Power of Negative Thinking -- Dealing in John Rawls: Primary Goods in a Just Society -- Don't Forget About the Health Benefits! -- Doyal and Gough's Theory of Human Needs -- Why Must My Rights Be Everyone's Rights? -- Giving an Inch and Taking a Mile: Can Health Care Include Xenotransplantation? -- No Religious Preference -- Conclusion -- VI Is Xenotransplantation Worth the Risk? -- Introduction -- Truth or Consequences: Incommensurability of Negativities