Almost everyone has been touched by at least a mild form of depression, and thus has some sense of what severe depressive illness must be like. In addition to the most serious clinical cases which can lead to institutionalization or even suicide, this book explores the "normal" depression we all experience--the inevitable blues that accompany troubled personal relationships, career setbacks, or the death of a loved one. It provides a compelling treatment of questions about the nature of depression, where it comes from, who's at risk, and what it indicates about human experience. Depression is a highly prevalent health problem, affecting about 11 million Americans every year. Its costs are staggering - $43.7 billion annually in lost productivity, lost income, and increased health care costs. These numbers put depression on a par with heart disease as one of the most expensive diseases in the United States today. But, unlike heart disease, depression is widely misunderstood. About two-thirds of the cases of depression go undiagnosed and untreated. With a compelling mix of information, illustration, and interpretation, David B. Cohen explores the current state of knowledge about depression, including the powerful influence of genetics. In addition to depressive illness, the book deals with related ideas and topics such as mourning, mania, the rhythms of sleep, self concepts, and suicide. Insights from psychology and psychiatry are blended with history, literature, current events, and personal observation, and topped off with a dose of common sense.

Advances in modern medicine - with the exception of psychiatry - are fantastic. Who would accept the surgical techniques of 1950, today? Which hospital would allow a surgeon fully trained in 1950 to even enter a modern surgical suite? In psychiatry, modern treatment does no better than it did in 1950. Psychiatry has the worst record of any medical specialty. This assessment is based on my observations from 1950 when I began to work in the mental hospitals in Saskatchewan. At that time patients were locked up in awful buildings placed far from centers of population. The treatment used by the Quakers in 1840, which yielded fifty percent discharge recoveries, was forgotten. Admission to mental hospital in 1950 was a life sentence, with no time off for good behaviour. The situation is different today. Patients are no longer locked up, but their brains are imprisoned by powerful, toxic chemicals from which they can not and are not allowed to escape. Orthomolecular treatment, which developed before these toxic drugs were found, has been ignored. Modern psychiatry uses only drugs and ignores the three most important elements of treatment, i.e. shelter, food, and treatment with civility and respect. The evidence is provided in this book. The optimum treatment in 1850 when drugs were not available yielded fifty percent recovery; today it is less than ten percent if the criteria are freedom from symptoms, ability to get along well with family and the community, and paying income tax.