"In 2008, a cheerful ambulance-chasing lawyer named Jay Shenk persuades the grieving Keener family to sue a private LA hospital. Their son Wesley has been transformed by a routine surgery into a kind of golem, absent all normal functioning or personality, walking in endless empty circles around his hospital room. In 2019, Shenk - still in practice but a shell of his former self - is hired to defend Wesley Keener's father when he is charged with murder . . . the murder, as it turns out, of the expert witness from the 2008 hospital case. Shenk's adopted son, a fragile teenager in 2008, is a wayward adult, though he may find his purpose when he investigates what really happened to the murdered witness. Two thrilling trials braid together, medical malpractice and murder, jostling us back and forth in time. The Quiet Boy is a book full of mysteries, not only about the death of a brilliant scientist, not only about the outcome of the medical malpractice suit, but about the relationship between children and their parents, between the past and the present, between truth and lies. At the center of it all is Wesley Keener, endlessly walking, staring empty-eyed, in whose quiet, hollow body may lie the fate of humankind."--Publisher.

In 1997, Stanley B. Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate. His struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement. In this book, Prusiner tells the remarkable story of his discovery of prions - infectious proteins that replicate and cause disease but surprisingly contain no genetic material - and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner's hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer's, Parkinson's, Lou Gehrig's and other devastating diseases of the brain?